AU760424B2 - Proteoglycan-reduced soft tissue xenografts - Google Patents

Proteoglycan-reduced soft tissue xenografts

Info

Publication number
AU760424B2
AU760424B2 AU29857/00A AU2985700A AU760424B2 AU 760424 B2 AU760424 B2 AU 760424B2 AU 29857/00 A AU29857/00 A AU 29857/00A AU 2985700 A AU2985700 A AU 2985700A AU 760424 B2 AU760424 B2 AU 760424B2
Authority
AU
Australia
Prior art keywords
xenograft
soft tissue
article
ligament
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU29857/00A
Other languages
English (en)
Other versions
AU2985700A (en
Inventor
Kevin R. Stone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crosscart Inc
Original Assignee
Crosscart Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crosscart Inc filed Critical Crosscart Inc
Publication of AU2985700A publication Critical patent/AU2985700A/en
Application granted granted Critical
Publication of AU760424B2 publication Critical patent/AU760424B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915—Method or apparatus for preparing biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
AU29857/00A 1999-02-11 2000-02-08 Proteoglycan-reduced soft tissue xenografts Ceased AU760424B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/248336 1999-02-11
US09/248,336 US6267786B1 (en) 1999-02-11 1999-02-11 Proteoglycan-reduced soft tissue xenografts
PCT/US2000/003233 WO2000047131A1 (en) 1999-02-11 2000-02-08 Proteoglycan-reduced soft tissue xenografts

Publications (2)

Publication Number Publication Date
AU2985700A AU2985700A (en) 2000-08-29
AU760424B2 true AU760424B2 (en) 2003-05-15

Family

ID=22938672

Family Applications (1)

Application Number Title Priority Date Filing Date
AU29857/00A Ceased AU760424B2 (en) 1999-02-11 2000-02-08 Proteoglycan-reduced soft tissue xenografts

Country Status (6)

Country Link
US (2) US6267786B1 (enExample)
EP (1) EP1158930A1 (enExample)
JP (2) JP5015376B2 (enExample)
AU (1) AU760424B2 (enExample)
CA (1) CA2361579A1 (enExample)
WO (1) WO2000047131A1 (enExample)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6972041B1 (en) * 1998-03-16 2005-12-06 Crosscart, Inc. Bone xenografts
US20030039678A1 (en) * 1998-03-16 2003-02-27 Stone Kevin R. Xenograft bone matrix for orthopedic applications
US6383732B1 (en) * 1999-02-11 2002-05-07 Crosscart, Inc. Method of preparing xenograft heart valves
WO1999051170A1 (en) * 1998-04-02 1999-10-14 Crosscart, Inc. Bone xenografts
US6214054B1 (en) 1998-09-21 2001-04-10 Edwards Lifesciences Corporation Method for fixation of biological tissues having mitigated propensity for post-implantation calcification and thrombosis and bioprosthetic devices prepared thereby
US6267786B1 (en) * 1999-02-11 2001-07-31 Crosscart, Inc. Proteoglycan-reduced soft tissue xenografts
US20030068815A1 (en) * 1999-02-11 2003-04-10 Stone Kevin R. Sterilized xenograft tissue
US6471723B1 (en) * 2000-01-10 2002-10-29 St. Jude Medical, Inc. Biocompatible prosthetic tissue
WO2002089711A1 (en) * 2001-05-07 2002-11-14 Crosscart, Inc. Submucosal xenografts
ATE543509T1 (de) 2001-08-13 2012-02-15 Univ Florida Material und verfahren zur förderung der reparatur von nervengewebe
US6878168B2 (en) 2002-01-03 2005-04-12 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
US7264966B2 (en) * 2002-01-23 2007-09-04 Olympus Optical Co., Ltd. Method of isolating cell or sample to be analyzed in cell
US7594934B2 (en) * 2002-06-14 2009-09-29 Crosscart, Inc. Galactosidase-treated prosthetic devices
US8106251B2 (en) 2002-08-21 2012-01-31 Revivicor, Inc. Tissue products derived from porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase
US7008763B2 (en) * 2002-09-23 2006-03-07 Cheung David T Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
AU2004238128B2 (en) * 2003-05-15 2008-10-30 Coretissue Bioengineering Inc. Method of removing cell
US7901457B2 (en) 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
EP1926459B1 (en) 2005-09-19 2015-01-07 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
EP2250884B1 (en) 2005-10-31 2012-12-05 Velico Medical, Inc. Novel alpha-galactosidases
EP2502493B1 (en) 2005-10-31 2017-12-06 Velico Medical, Inc. Novel alpha-galactosidases
US20070299517A1 (en) * 2006-06-21 2007-12-27 Howmedica Osteonics Corp. Articular cartilage implant
CN101332316B (zh) * 2008-07-22 2012-12-26 广东冠昊生物科技股份有限公司 生物型鼻梁植入体
WO2008045807A2 (en) 2006-10-09 2008-04-17 Active Implants Corporation Meniscus prosthetic device
US8192491B2 (en) 2006-10-09 2012-06-05 Active Implants Corporation Meniscus prosthetic device
WO2008073582A2 (en) 2006-10-27 2008-06-19 Edwards Lifesciences Corporation Biological tissue for surgical implantation
US9056151B2 (en) * 2007-02-12 2015-06-16 Warsaw Orthopedic, Inc. Methods for collagen processing and products using processed collagen
US20080260794A1 (en) * 2007-02-12 2008-10-23 Lauritzen Nels J Collagen products and methods for producing collagen products
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
US20080255665A1 (en) * 2007-04-11 2008-10-16 Active Implants Corporation Anchored prosthetic meniscus device
US20080306610A1 (en) * 2007-06-07 2008-12-11 Zimmer Orthobiologics, Inc. Tissue processing for nonimmunogenic implants
US9101691B2 (en) 2007-06-11 2015-08-11 Edwards Lifesciences Corporation Methods for pre-stressing and capping bioprosthetic tissue
US8162961B2 (en) 2007-07-23 2012-04-24 Zimmer Orthobiologies, Inc. Medical devices and methods for cutting and suturing biological tissue
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
US20090181807A1 (en) * 2008-01-16 2009-07-16 Jason Miguel De Los Santos Golfing aid
KR100947553B1 (ko) * 2008-02-14 2010-03-12 주식회사 바이오랜드 생체조직 이식재 및 그의 제조 방법
WO2009111069A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US20090286289A1 (en) * 2008-03-10 2009-11-19 Pang Danny Z Production of Hyaluronate Unsaturated Disaccharides and its Application
US8361147B2 (en) 2008-04-09 2013-01-29 Active Implants Corporation Meniscus prosthetic devices with anti-migration features
US7611653B1 (en) 2008-04-09 2009-11-03 Active Implants Corporation Manufacturing and material processing for prosthetic devices
US7991599B2 (en) 2008-04-09 2011-08-02 Active Implants Corporation Meniscus prosthetic device selection and implantation methods
US8016884B2 (en) 2008-04-09 2011-09-13 Active Implants Corporation Tensioned meniscus prosthetic devices and associated methods
US9277999B2 (en) * 2009-02-27 2016-03-08 University of Pittsburgh—of the Commonwealth System of Higher Education Joint bioscaffolds
EP2674174B1 (en) 2010-03-23 2019-10-16 Edwards Lifesciences Corporation Methods of conditioning sheet bioprosthetic tissue
US8460691B2 (en) 2010-04-23 2013-06-11 Warsaw Orthopedic, Inc. Fenestrated wound repair scaffold
US8790699B2 (en) 2010-04-23 2014-07-29 Warsaw Orthpedic, Inc. Foam-formed collagen strand
EP2568926B1 (en) 2010-05-06 2014-12-10 Stichting Katholieke Universiteit Non-resorbable meniscus prosthesis for the human knee joint
US8906601B2 (en) 2010-06-17 2014-12-09 Edwardss Lifesciences Corporation Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
CN102946916B (zh) 2010-06-17 2015-03-18 爱德华兹生命科学公司 通过化学修饰抗原性碳水化合物稳定生物假体组织的方法
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
US9351829B2 (en) 2010-11-17 2016-05-31 Edwards Lifesciences Corporation Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability
DE102011008604A1 (de) 2011-01-14 2012-07-19 Tutogen Medical Gmbh Herstellung eines Transplantats aus tierischer Dermis mit Natriumsulfidlösung
US9238793B2 (en) 2011-04-28 2016-01-19 Lifecell Corporation Method for enzymatic treatment of tissue products
EP2701755B1 (en) 2011-04-28 2019-01-16 LifeCell Corporation Method for enzymatic treatment of tissue products
US10207025B2 (en) 2011-04-28 2019-02-19 Lifecell Corporation Method for enzymatic treatment of tissue products
US9540610B2 (en) 2011-04-28 2017-01-10 Warsaw Orthopedic, Inc. Collagen and cell implant
KR20150035588A (ko) 2012-05-11 2015-04-06 알티아이 서지칼, 인크. 이종이식 연조직 이식물 및 제조 및 사용 방법
US10238771B2 (en) 2012-11-08 2019-03-26 Edwards Lifesciences Corporation Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system
US9615922B2 (en) 2013-09-30 2017-04-11 Edwards Lifesciences Corporation Method and apparatus for preparing a contoured biological tissue
US10959839B2 (en) 2013-10-08 2021-03-30 Edwards Lifesciences Corporation Method for directing cellular migration patterns on a biological tissue
DK3065790T3 (da) * 2013-11-04 2021-02-01 Lifecell Corp Fremgangsmåder til fjernelse af alpha-galactose
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
JP2020513944A (ja) 2017-01-30 2020-05-21 ライフセル コーポレーションＬｉｆｅＣｅｌｌ Ｃｏｒｐｏｒａｔｉｏｎ 組織マトリックス材料および酵素接着剤
WO2018140853A1 (en) 2017-01-30 2018-08-02 Lifecell Corporation Transglutaminase treated products
WO2018222434A1 (en) 2017-05-31 2018-12-06 Edwards Lifesciences Corporation Collagen fibers and articles formed therefrom
EP3743124B1 (en) 2018-01-23 2024-05-08 Edwards Lifesciences Corporation Method for pre-stretching implantable biocompatible materials, and materials and devices produced thereby
CN113164258B (zh) 2018-11-01 2024-08-27 爱德华兹生命科学公司 经导管再生肺动脉瓣
KR102559788B1 (ko) * 2022-04-21 2023-07-27 주식회사 티앤알바이오팹 다단계 탈세포화된 조직 매트릭스 및 이의 제조방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5782915A (en) * 1995-09-15 1998-07-21 Stone; Kevin R. Articular cartilage heterografts

Family Cites Families (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1045752A (en) 1975-05-26 1979-01-09 Robert W. Jackson Prosthetic implant
JPS55122544A (en) * 1979-03-15 1980-09-20 Seikagaku Kogyo Co Ltd Preparation of bone for transplantation
US4344193A (en) 1980-11-28 1982-08-17 Kenny Charles H Meniscus prosthesis
US4400833A (en) 1981-06-10 1983-08-30 Kurland Kenneth Z Means and method of implanting bioprosthetics
US4502161A (en) 1981-09-21 1985-03-05 Wall W H Prosthetic meniscus for the repair of joints
SE446372B (sv) 1983-02-03 1986-09-08 Medinvent Sa Blodkerlsprotes for anvendning som shunt mellan blodkerl
IL68218A (en) 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
US4801299A (en) 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
US4609627A (en) 1983-08-01 1986-09-02 New York Blood Center, Inc. Enzymatic conversion of certain sub-type A and AB erythrocytes
US4932973A (en) 1983-09-30 1990-06-12 El Gendler Cartilage and bone induction by artificially perforated organic bone matrix
US4789663A (en) 1984-07-06 1988-12-06 Collagen Corporation Methods of bone repair using collagen
US4597266A (en) 1985-05-28 1986-07-01 Cryolife, Inc. Freezing agent and container
US4678470A (en) 1985-05-29 1987-07-07 American Hospital Supply Corporation Bone-grafting material
US4627853A (en) 1985-05-29 1986-12-09 American Hospital Supply Corporation Method of producing prostheses for replacement of articular cartilage and prostheses so produced
US4755593A (en) 1985-07-24 1988-07-05 Lauren Mark D Novel biomaterial of cross-linked peritoneal tissue
US4902295A (en) 1985-08-26 1990-02-20 Hana Biologics, Inc. Transplantable artificial tissue
GB8618374D0 (en) 1986-07-28 1986-09-03 Hsc Res Dev Corp Biological vascular prostheses
US4846835A (en) 1987-06-15 1989-07-11 Grande Daniel A Technique for healing lesions in cartilage
US4880429A (en) 1987-07-20 1989-11-14 Stone Kevin R Prosthetic meniscus
US5263984A (en) * 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US5158574A (en) 1987-07-20 1992-10-27 Regen Corporation Prosthetic meniscus
US5306311A (en) 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
US5007934A (en) * 1987-07-20 1991-04-16 Regen Corporation Prosthetic meniscus
US5116374A (en) 1989-03-02 1992-05-26 Regen Corporation Prosthetic meniscus
US5078744A (en) 1987-09-04 1992-01-07 Bio-Products, Inc. Method of using tendon/ligament substitutes composed of long, parallel, non-antigenic tendon/ligament fibers
US5071741A (en) 1988-04-18 1991-12-10 Cryolife, Inc. Cryoprotective agent and its use in cryopreservation of cellular matter
US5171273A (en) 1989-01-13 1992-12-15 University Of Medicine And Dentistry Of New Jersey Synthetic collagen orthopaedic structures such as grafts, tendons and other structures
US5067962A (en) 1989-04-18 1991-11-26 Baxter International Inc. Bioprosthetic ligament
US5171660A (en) 1989-04-26 1992-12-15 Cryolife, Inc. Process of revitalizing cells and tissue prior to cryopreservation
US5521087A (en) 1989-05-10 1996-05-28 Massachusetts Institute Of Technology Method for producing oriented connective tissue cells in a ligament configuration
US5131850A (en) 1989-11-03 1992-07-21 Cryolife, Inc. Method for cryopreserving musculoskeletal tissues
US5092894A (en) 1990-02-13 1992-03-03 Kenny Charles H Stabilized meniscus prosthesis
US5171322A (en) 1990-02-13 1992-12-15 Kenny Charles H Stabilized meniscus prosthesis
ES2076467T3 (es) 1990-10-31 1995-11-01 El Gendler Membranas flexibles producidas con materia de hueso organica para la reparacion y reconstruccion de partes del esqueleto.
US5192312A (en) 1991-03-05 1993-03-09 Colorado State University Research Foundation Treated tissue for implantation and methods of treatment and use
US5160313A (en) 1991-05-14 1992-11-03 Cryolife, Inc. Process for preparing tissue for transplantation
US5216126A (en) 1991-06-19 1993-06-01 Genentech, Inc. Receptor polypeptides and their production and uses
US5507810A (en) 1991-10-07 1996-04-16 Osteotech, Inc. Processing of fibrous connective tissue
US5333626A (en) 1991-12-31 1994-08-02 Cryolife, Inc. Preparation of bone for transplantation
US6537574B1 (en) 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US5352463A (en) * 1992-11-13 1994-10-04 Badylak Steven F Tissue graft for surgical reconstruction of a collagenous meniscus and method therefor
FR2699408B1 (fr) * 1992-12-21 1995-03-24 Bioland Procédé de traitement de tissus osseux et biomatériaux implantables correspondants.
US5358525A (en) 1992-12-28 1994-10-25 Fox John E Bearing surface for prosthesis and replacement of meniscal cartilage
EP0871414B1 (en) 1994-03-14 2004-04-28 Cryolife, Inc Preparation methods of tissue for implantation
WO1995026740A1 (en) 1994-03-31 1995-10-12 Diacrin, Inc. Improved methods for transplantation using modified cells and t cell inhibitory agents
CA2187802A1 (en) 1994-04-13 1995-10-26 Manfred W. Baetscher .alpha.(1,3) galactosyltransferase negative swine
CA2191891A1 (en) 1994-06-03 1995-12-14 Albert Edge Modified cells and methods for inhibiting hyperacute rejection of xenogeneic transplants
US5516532A (en) 1994-08-05 1996-05-14 Children's Medical Center Corporation Injectable non-immunogenic cartilage and bone preparation
US5904716A (en) 1995-04-26 1999-05-18 Gendler; El Method for reconstituting cartilage tissue using demineralized bone and product thereof
US5913900A (en) * 1995-06-07 1999-06-22 Corsscart, Inc. Substantially native meniscal cartilage heterografts
US5865849A (en) * 1995-06-07 1999-02-02 Crosscart, Inc. Meniscal heterografts
US6110206A (en) * 1995-09-15 2000-08-29 Crosscart, Inc. Anterior cruciate ligament xenografts
US6049025A (en) * 1995-09-15 2000-04-11 Stone; Kevin R. Articular cartilage xenografts
US6166288A (en) * 1995-09-27 2000-12-26 Nextran Inc. Method of producing transgenic animals for xenotransplantation expressing both an enzyme masking or reducing the level of the gal epitope and a complement inhibitor
AUPO182396A0 (en) * 1996-08-23 1996-09-12 Austin Research Institute, The Improved nucleic acids for reducing carbohydrate epitopes
US6267786B1 (en) * 1999-02-11 2001-07-31 Crosscart, Inc. Proteoglycan-reduced soft tissue xenografts

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
US5782915A (en) * 1995-09-15 1998-07-21 Stone; Kevin R. Articular cartilage heterografts

Also Published As

Publication number Publication date
EP1158930A1 (en) 2001-12-05
JP2012166039A (ja) 2012-09-06
CA2361579A1 (en) 2000-08-17
JP5015376B2 (ja) 2012-08-29
JP5654516B2 (ja) 2015-01-14
WO2000047131A1 (en) 2000-08-17
AU2985700A (en) 2000-08-29
JP2002536109A (ja) 2002-10-29
US20010039459A1 (en) 2001-11-08
US6267786B1 (en) 2001-07-31
US6455309B2 (en) 2002-09-24

Similar Documents

Publication Publication Date Title
AU760424B2 (en) Proteoglycan-reduced soft tissue xenografts
US6231608B1 (en) Aldehyde and glycosidase-treated soft and bone tissue xenografts
AU759086B2 (en) Soft tissue xenografts
US6046379A (en) Meniscal xenografts
US5984858A (en) Meniscal xenografts
US5944755A (en) Articular cartilage xenografts
US6049025A (en) Articular cartilage xenografts
US6110206A (en) Anterior cruciate ligament xenografts
US5865849A (en) Meniscal heterografts
US5913900A (en) Substantially native meniscal cartilage heterografts
US5782915A (en) Articular cartilage heterografts
US20010051828A1 (en) Anterior cruciate ligament xenografts
US7594934B2 (en) Galactosidase-treated prosthetic devices
WO2001091671A1 (en) Xenograft heart valves
US6210440B1 (en) Anterior cruciate ligament xenografts

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)