AU753703B2 - Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction - Google Patents

Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction

Info

Publication number
AU753703B2
AU753703B2 AU52381/99A AU5238199A AU753703B2 AU 753703 B2 AU753703 B2 AU 753703B2 AU 52381/99 A AU52381/99 A AU 52381/99A AU 5238199 A AU5238199 A AU 5238199A AU 753703 B2 AU753703 B2 AU 753703B2
Authority
AU
Australia
Prior art keywords
seq
polypeptide
nucleic acid
receptor
gpcr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU52381/99A
Other languages
English (en)
Other versions
AU5238199A (en
Inventor
Jon Elliot Adler
Mark Hoon
Juergen Lindemeier
Nick Ryba
Charles S. Zuker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
US Department of Health and Human Services
Original Assignee
University of California Berkeley
University of California San Diego UCSD
US Department of Health and Human Services
Government of the United States of America
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California Berkeley, University of California San Diego UCSD, US Department of Health and Human Services, Government of the United States of America filed Critical University of California Berkeley
Publication of AU5238199A publication Critical patent/AU5238199A/en
Application granted granted Critical
Publication of AU753703B2 publication Critical patent/AU753703B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU52381/99A 1998-07-28 1999-07-27 Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction Expired AU753703B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9446598P 1998-07-28 1998-07-28
US60/094465 1998-07-28
PCT/US1999/017099 WO2000006592A1 (en) 1998-07-28 1999-07-27 Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2002317537A Division AU2002317537A1 (en) 1998-07-28 2002-12-12 Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction

Publications (2)

Publication Number Publication Date
AU5238199A AU5238199A (en) 2000-02-21
AU753703B2 true AU753703B2 (en) 2002-10-24

Family

ID=22245353

Family Applications (1)

Application Number Title Priority Date Filing Date
AU52381/99A Expired AU753703B2 (en) 1998-07-28 1999-07-27 Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction

Country Status (12)

Country Link
US (3) US20030036630A1 (https=)
EP (1) EP1100810A4 (https=)
JP (2) JP2002521049A (https=)
KR (1) KR100602857B1 (https=)
CN (1) CN1198836C (https=)
AU (1) AU753703B2 (https=)
BR (1) BR9912545A (https=)
CA (2) CA2776054C (https=)
IL (2) IL140979A0 (https=)
NO (1) NO20010363L (https=)
WO (1) WO2000006592A1 (https=)
ZA (1) ZA200100401B (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
WO2000045179A2 (en) * 1999-01-27 2000-08-03 The Regents Of The University Of California Screening for modulators of g-protein subunit beta 3
US6929925B1 (en) 1999-01-27 2005-08-16 The Regents Of The University Of California Assays for sensory modulators using a sensory cell specific G-protein beta subunit
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
WO2001072842A2 (en) * 2000-03-28 2001-10-04 Lexicon Genetics Incorporated Human 7-transmembrane proteins and polynucleotides encoding the same
CA2408140A1 (en) * 2000-05-22 2001-11-29 Incyte Genomics, Inc. G-protein coupled receptors
EP2093293A3 (en) * 2000-06-16 2010-07-07 Incyte Corporation G-Protein coupled receptors
CA2424821A1 (en) * 2000-10-10 2002-04-18 Pe Corporation (Ny) Gene encoding a human g-protein coupled receptor and its use
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
US7368285B2 (en) 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US7309577B2 (en) 2001-03-07 2007-12-18 Senomyx, Inc. Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
US7763431B1 (en) 2001-03-07 2010-07-27 Senomyx, Inc. Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
US7301009B2 (en) 2001-06-26 2007-11-27 Senomyx, Inc. Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli
US20080244761A1 (en) 2001-03-07 2008-10-02 Senomyx, Inc. T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
EP1572871A4 (en) * 2001-04-20 2007-11-14 Sinai School Medicine T1R3, A NEW TASTE RECEPTOR
DK2327985T3 (en) 2001-06-26 2016-09-05 Senomyx Inc H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds
CN108329393A (zh) * 2001-06-26 2018-07-27 塞诺米克斯公司 T1r异源寡聚的味觉受体和表达所述受体的细胞系及其在鉴定味觉化合物中的用途
EP2293067B1 (en) 2001-06-26 2016-04-20 Senomyx, Inc. T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
AU2002336571A1 (en) * 2001-09-18 2003-04-01 Irm, Llc Sweet taste receptors
US7527944B2 (en) 2003-06-27 2009-05-05 Monell Chemical Senses Center Taste receptors of the T1R family from domestic cat
AR046078A1 (es) 2003-08-06 2005-11-23 Senomyx Inc Nuevos sabores, modificadores de sabores, sustancias gustativas, mejoradores de gusto, sustancias gustativas y/o mejoradoras del gusto umani o dulce y uso de los mismos.
US8796441B2 (en) 2005-04-13 2014-08-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Human sweet and umami taste receptor variants
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US20110097741A1 (en) * 2006-04-20 2011-04-28 Jay Patrick Slack Partial t1r2 nucleic acid sequence, receptor protein and its use in screening assays
ES2640453T3 (es) 2006-04-21 2017-11-03 Senomyx, Inc. Procesos para preparar composiciones saborizantes sólidas
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
US9128079B2 (en) 2011-08-08 2015-09-08 The Coca-Cola Company Methods of using lung or bronchial epithelial cells to identify bitter taste modulators
US9804157B1 (en) 2013-03-15 2017-10-31 Senomyx, Inc. Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives
WO2021150686A1 (en) 2020-01-22 2021-07-29 Firmenich Incorporated High-sensitivity detection of gpcr activity and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146501A (en) * 1975-12-12 1979-03-27 Henkin Robert I Process for isolating and purifying taste bud receptors for screening and evaluating tastants
US5688662A (en) * 1992-04-09 1997-11-18 Linguagen Corporation Gustducin polynucleotides, vectors, host cells and recombinant methods
US7368285B2 (en) * 2001-03-07 2008-05-06 Senomyx, Inc. Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same
US8039233B2 (en) * 2007-01-18 2011-10-18 Givaudan S.A. Nucleic acid sequences and their use in methods to identify umami modulatiors

Also Published As

Publication number Publication date
WO2000006592A1 (en) 2000-02-10
CA2335318C (en) 2012-05-01
US20070185312A1 (en) 2007-08-09
NO20010363D0 (no) 2001-01-22
US20030036630A1 (en) 2003-02-20
AU5238199A (en) 2000-02-21
CA2335318A1 (en) 2000-02-10
CA2776054C (en) 2016-08-30
EP1100810A4 (en) 2002-09-18
CN1198836C (zh) 2005-04-27
BR9912545A (pt) 2001-10-30
JP2009261399A (ja) 2009-11-12
CN1317010A (zh) 2001-10-10
US20090148948A1 (en) 2009-06-11
KR100602857B1 (ko) 2006-07-20
IL140979A (en) 2008-07-08
NO20010363L (no) 2001-03-26
CA2776054A1 (en) 2000-02-10
KR20010085306A (ko) 2001-09-07
WO2000006592A9 (en) 2000-11-02
EP1100810A1 (en) 2001-05-23
JP2002521049A (ja) 2002-07-16
ZA200100401B (en) 2001-10-31
IL140979A0 (en) 2002-02-10

Similar Documents

Publication Publication Date Title
AU753703B2 (en) Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
AU764180B2 (en) Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
US7888045B2 (en) Methods for identifying modulators of SF taste receptor signaling
US20090104703A1 (en) Nucleic Acids Encoding Proteins Involved in Sensory Transduction
US6929925B1 (en) Assays for sensory modulators using a sensory cell specific G-protein beta subunit
WO2000045179A2 (en) Screening for modulators of g-protein subunit beta 3
US6623939B1 (en) Nucleic acids encoding a G protein gamma subunit involved in sensory transduction
EP1806362B1 (en) Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
HK1101639B (en) Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired