AU746443B2 - Characterising nucleic acid by mass spectrometry - Google Patents

Characterising nucleic acid by mass spectrometry Download PDF

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Publication number
AU746443B2
AU746443B2 AU90887/98A AU9088798A AU746443B2 AU 746443 B2 AU746443 B2 AU 746443B2 AU 90887/98 A AU90887/98 A AU 90887/98A AU 9088798 A AU9088798 A AU 9088798A AU 746443 B2 AU746443 B2 AU 746443B2
Authority
AU
Australia
Prior art keywords
mass
nucleic acid
fragments
labels
population
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU90887/98A
Other languages
English (en)
Other versions
AU9088798A (en
Inventor
Gunter Schmidt
Andrew Hugin Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xzillion GmbH and Co KG
Original Assignee
Brax Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9719638.0A external-priority patent/GB9719638D0/en
Priority claimed from GBGB9725630.9A external-priority patent/GB9725630D0/en
Application filed by Brax Group Ltd filed Critical Brax Group Ltd
Publication of AU9088798A publication Critical patent/AU9088798A/en
Application granted granted Critical
Publication of AU746443B2 publication Critical patent/AU746443B2/en
Assigned to XZILLION GMBH & CO. KG reassignment XZILLION GMBH & CO. KG Alteration of Name(s) in Register under S187 Assignors: BRAX GROUP LIMITED
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6872—Methods for sequencing involving mass spectrometry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU90887/98A 1997-09-15 1998-09-15 Characterising nucleic acid by mass spectrometry Ceased AU746443B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9719638 1997-09-15
GBGB9719638.0A GB9719638D0 (en) 1997-09-15 1997-09-15 High throughput analysis of sanger dna ladders by tandem mass spectrometry
GB9725630 1997-12-03
GBGB9725630.9A GB9725630D0 (en) 1997-12-03 1997-12-03 Charecterising nucleic acid
PCT/GB1998/002789 WO1999014362A1 (en) 1997-09-15 1998-09-15 Characterising nucleic acid by mass spectrometry

Publications (2)

Publication Number Publication Date
AU9088798A AU9088798A (en) 1999-04-05
AU746443B2 true AU746443B2 (en) 2002-05-02

Family

ID=26312254

Family Applications (1)

Application Number Title Priority Date Filing Date
AU90887/98A Ceased AU746443B2 (en) 1997-09-15 1998-09-15 Characterising nucleic acid by mass spectrometry

Country Status (6)

Country Link
EP (1) EP1015632A1 (xx)
JP (1) JP2001516591A (xx)
AU (1) AU746443B2 (xx)
CA (1) CA2303790A1 (xx)
NZ (1) NZ503289A (xx)
WO (1) WO1999014362A1 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19824280B4 (de) * 1998-05-29 2004-08-19 Bruker Daltonik Gmbh Mutationsanalyse mittels Massenspektrometrie
GB0006141D0 (en) 2000-03-14 2000-05-03 Brax Group Ltd Mass labels
EP1373561B1 (en) * 2000-06-13 2009-02-18 The Trustees of Boston University Use of mass-matched nucleotides in the analysis of oligonucleotide mixtures and in highly multiplexed nucleic acid sequencing
ES2296996T3 (es) 2001-09-14 2008-05-01 Electrophoretics Limited Marcaje de moleculas.
US7195751B2 (en) 2003-01-30 2007-03-27 Applera Corporation Compositions and kits pertaining to analyte determination
US20050148087A1 (en) 2004-01-05 2005-07-07 Applera Corporation Isobarically labeled analytes and fragment ions derived therefrom

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2215797A (en) * 1996-03-19 1997-10-10 Vital-Tech Ltd. Body and joints massage device
AU4566397A (en) * 1996-10-04 1998-05-05 Brax Genomics Limited Nucleic acid sequencing by adaptator ligation
AU5974498A (en) * 1997-02-18 1998-09-09 Kinetic Limited Control arrangement for vehicle suspension system

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5547835A (en) * 1993-01-07 1996-08-20 Sequenom, Inc. DNA sequencing by mass spectrometry
AU687801B2 (en) * 1993-03-19 1998-03-05 Sequenom, Inc. DNA sequencing by mass spectrometry via exonuclease degradation
GB9504598D0 (en) * 1995-03-03 1995-04-26 Imp Cancer Res Tech Method of nucleic acid analysis
DE69701671T3 (de) * 1996-01-23 2006-08-17 Qiagen Genomics, Inc., Bothell Verfahren und zusammenstellungen zur sequenzbestimmung von nukleinsäuremolekülen
EP0886681A1 (en) * 1996-03-04 1998-12-30 Genetrace Systems, Inc. Methods of screening nucleic acids using mass spectrometry
WO1997037041A2 (en) * 1996-03-18 1997-10-09 Sequenom, Inc. Dna sequencing by mass spectrometry
CA2274587A1 (en) * 1996-12-10 1998-06-18 Genetrace Systems Inc. Releasable nonvolatile mass-label molecules
AU725966B2 (en) * 1997-01-15 2000-10-26 Xzillion Gmbh & Co. Kg Mass label linked hybridisation probes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2215797A (en) * 1996-03-19 1997-10-10 Vital-Tech Ltd. Body and joints massage device
AU4566397A (en) * 1996-10-04 1998-05-05 Brax Genomics Limited Nucleic acid sequencing by adaptator ligation
AU5974498A (en) * 1997-02-18 1998-09-09 Kinetic Limited Control arrangement for vehicle suspension system

Also Published As

Publication number Publication date
NZ503289A (en) 2002-11-26
AU9088798A (en) 1999-04-05
JP2001516591A (ja) 2001-10-02
CA2303790A1 (en) 1999-03-25
WO1999014362A1 (en) 1999-03-25
EP1015632A1 (en) 2000-07-05

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: XZILLION GMBH AND CO KG

Free format text: FORMER OWNER WAS: BRAX GROUP LIMITED