AU745409B2 - Multiple site delivery of adenoviral vector for the induction of angiogenesis - Google Patents

Multiple site delivery of adenoviral vector for the induction of angiogenesis Download PDF

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Publication number
AU745409B2
AU745409B2 AU62530/98A AU6253098A AU745409B2 AU 745409 B2 AU745409 B2 AU 745409B2 AU 62530/98 A AU62530/98 A AU 62530/98A AU 6253098 A AU6253098 A AU 6253098A AU 745409 B2 AU745409 B2 AU 745409B2
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AU
Australia
Prior art keywords
tissue
vector
target tissue
multiple applications
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU62530/98A
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English (en)
Other versions
AU6253098A (en
Inventor
Ronald G. Crystal
Todd K. Rosengart
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Cornell Research Foundation Inc
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Cornell Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/801,352 external-priority patent/US5846225A/en
Application filed by Cornell Research Foundation Inc filed Critical Cornell Research Foundation Inc
Publication of AU6253098A publication Critical patent/AU6253098A/en
Application granted granted Critical
Publication of AU745409B2 publication Critical patent/AU745409B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Accommodation For Nursing Or Treatment Tables (AREA)
AU62530/98A 1997-01-29 1998-01-29 Multiple site delivery of adenoviral vector for the induction of angiogenesis Ceased AU745409B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US3660197P 1997-01-29 1997-01-29
US60/036601 1997-01-29
US08/801352 1997-02-19
US08/801,352 US5846225A (en) 1997-02-19 1997-02-19 Gene transfer therapy delivery device and method
US7115698P 1998-01-13 1998-01-13
US60/071156 1998-01-13
PCT/US1998/001638 WO1998032859A1 (en) 1997-01-29 1998-01-29 Multiple site delivery of adenoviral vector for the induction of angiogenesis

Publications (2)

Publication Number Publication Date
AU6253098A AU6253098A (en) 1998-08-18
AU745409B2 true AU745409B2 (en) 2002-03-21

Family

ID=27365066

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62530/98A Ceased AU745409B2 (en) 1997-01-29 1998-01-29 Multiple site delivery of adenoviral vector for the induction of angiogenesis

Country Status (16)

Country Link
US (2) US6518255B2 (enExample)
EP (1) EP1012291B1 (enExample)
JP (1) JP2001509168A (enExample)
KR (1) KR20000070572A (enExample)
AT (1) ATE279518T1 (enExample)
AU (1) AU745409B2 (enExample)
BR (1) BR9806819A (enExample)
CA (1) CA2278621A1 (enExample)
DE (1) DE69827021T2 (enExample)
HU (1) HUP0001964A3 (enExample)
IL (1) IL131021A0 (enExample)
MX (1) MXPA99006993A (enExample)
NO (1) NO993669L (enExample)
NZ (1) NZ336838A (enExample)
PL (1) PL334902A1 (enExample)
WO (1) WO1998032859A1 (enExample)

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US6855160B1 (en) 1999-08-04 2005-02-15 C. R. Bard, Inc. Implant and agent delivery device
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HK1048593A1 (zh) * 1999-11-05 2003-04-11 The Regents Of The University Of California 用於通过体内基因输送治疗心血管疾病的技术和组合物
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US20090196850A1 (en) 2005-01-06 2009-08-06 Novo Nordisk A/S Anti-Kir Combination Treatments and Methods
RU2321631C2 (ru) * 2005-06-24 2008-04-10 Государственное учреждение Российский научный центр хирургии РАМН Неинфекционный для человека аденовирус как вектор для заместительной генной терапии нарушений ангиогенеза, обеспечивающий эффективный синтез ангиогенина человека в трансфецированных клетках млекопитающих, способ индукции ангиогенеза, способ лечения ишемической болезни, композиция для индукции ангиогенеза и лечения ишемической болезни
US7751883B2 (en) 2006-04-25 2010-07-06 Eugenio Picano System and method for promoting coronary angiogenesis
US9598673B2 (en) * 2006-05-19 2017-03-21 Creative Medical Health Treatment of disc degenerative disease
US8983570B2 (en) * 2007-03-27 2015-03-17 Cardiovascular Biotherapeutics, Inc. Therapeutic angiogenesis for treatment of the spine
US11224635B2 (en) 2007-03-27 2022-01-18 Venturis Thereuptics, Inc. Therapeutic angiogenesis for treatment of the spine and other tissues
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CA2772610C (en) 2009-08-28 2018-01-23 The Cleveland Clinic Foundation Sdf-1 delivery for treating ischemic tissue
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PT2945642T (pt) * 2013-01-17 2024-05-27 Medizinische Hochschule Hannover Proteína do fator 1 para utilização no tratamento ou prevenção de doenças
WO2016134293A1 (en) 2015-02-20 2016-08-25 Baylor College Of Medicine p63 INACTIVATION FOR THE TREATMENT OF HEART FAILURE
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Also Published As

Publication number Publication date
NZ336838A (en) 2002-04-26
EP1012291A1 (en) 2000-06-28
AU6253098A (en) 1998-08-18
BR9806819A (pt) 2000-05-09
NO993669D0 (no) 1999-07-28
KR20000070572A (ko) 2000-11-25
DE69827021T2 (de) 2005-02-24
HUP0001964A2 (hu) 2000-10-28
IL131021A0 (en) 2001-01-28
DE69827021D1 (de) 2004-11-18
EP1012291B1 (en) 2004-10-13
NO993669L (no) 1999-09-27
JP2001509168A (ja) 2001-07-10
US20030103943A1 (en) 2003-06-05
WO1998032859A1 (en) 1998-07-30
MXPA99006993A (es) 2005-06-01
ATE279518T1 (de) 2004-10-15
US20010041679A1 (en) 2001-11-15
US6518255B2 (en) 2003-02-11
PL334902A1 (en) 2000-03-27
HUP0001964A3 (en) 2002-01-28
CA2278621A1 (en) 1998-07-30

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