AU737771B2 - Method and kit for the detection of mutations in DNA's using restriction enzymes - Google Patents

Method and kit for the detection of mutations in DNA's using restriction enzymes Download PDF

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Publication number
AU737771B2
AU737771B2 AU43022/97A AU4302297A AU737771B2 AU 737771 B2 AU737771 B2 AU 737771B2 AU 43022/97 A AU43022/97 A AU 43022/97A AU 4302297 A AU4302297 A AU 4302297A AU 737771 B2 AU737771 B2 AU 737771B2
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AU
Australia
Prior art keywords
primers
detection
supports
label
pcr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU43022/97A
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English (en)
Other versions
AU4302297A (en
Inventor
Ursula Bilitewski
Dirk Kuhlmeier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
Original Assignee
Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
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Publication date
Application filed by Helmholtz Zentrum fuer Infektionsforschung HZI GmbH filed Critical Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
Publication of AU4302297A publication Critical patent/AU4302297A/en
Application granted granted Critical
Publication of AU737771B2 publication Critical patent/AU737771B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU43022/97A 1997-05-21 1997-09-10 Method and kit for the detection of mutations in DNA's using restriction enzymes Ceased AU737771B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19721327 1997-05-21
DE19721327 1997-05-21
DE19739612 1997-09-09
DE19739612 1997-09-09
PCT/EP1997/004955 WO1998053098A1 (de) 1997-05-21 1997-09-10 Verfahren und kit zur detektion von mutationen in dna's mit hilfe von restriktionsenzymen

Publications (2)

Publication Number Publication Date
AU4302297A AU4302297A (en) 1998-12-11
AU737771B2 true AU737771B2 (en) 2001-08-30

Family

ID=26036720

Family Applications (1)

Application Number Title Priority Date Filing Date
AU43022/97A Ceased AU737771B2 (en) 1997-05-21 1997-09-10 Method and kit for the detection of mutations in DNA's using restriction enzymes

Country Status (6)

Country Link
EP (1) EP0983379A1 (ru)
JP (1) JP2001525678A (ru)
AU (1) AU737771B2 (ru)
CA (1) CA2290510A1 (ru)
RU (1) RU2193069C2 (ru)
WO (1) WO1998053098A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR221400A0 (en) * 2000-12-20 2001-01-25 Murdoch Childrens Research Institute, The Diagnostic assay
EP2199410A1 (en) * 2003-03-19 2010-06-23 The University Of British Columbia Plasminogen activator inhibitor-1 (PAI-1) Polymorphism useful as indicators of patient outcome

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017262A1 (en) * 1990-04-30 1991-11-14 The University Of British Columbia Method of establishing identity
WO1995025538A1 (en) * 1994-03-18 1995-09-28 The General Hospital Corporation Cleaved amplified rflp detection methods
WO1997009444A1 (en) * 1995-09-01 1997-03-13 Variagenics, Inc. Detection of mismatches by resolvase cleavage using a magnetic bead support

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118605A (en) * 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
WO1995002068A1 (fr) * 1993-07-09 1995-01-19 Wakunaga Seiyaku Kabushiki Kaisha Methode de discrimination des acides nucleiques et necessaire d'essai a cette fin
FR2718461B1 (fr) * 1994-04-07 1996-05-15 Cis Bio Int Procédé de détection d'un site de restriction dans une séquence d'ADN.
AU703951B2 (en) * 1995-05-11 1999-04-01 Arild Lagerkvist Detection of mismatches by resolvase cleavage on a solid support
US5753439A (en) * 1995-05-19 1998-05-19 Trustees Of Boston University Nucleic acid detection methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017262A1 (en) * 1990-04-30 1991-11-14 The University Of British Columbia Method of establishing identity
WO1995025538A1 (en) * 1994-03-18 1995-09-28 The General Hospital Corporation Cleaved amplified rflp detection methods
WO1997009444A1 (en) * 1995-09-01 1997-03-13 Variagenics, Inc. Detection of mismatches by resolvase cleavage using a magnetic bead support

Also Published As

Publication number Publication date
AU4302297A (en) 1998-12-11
RU2193069C2 (ru) 2002-11-20
CA2290510A1 (en) 1998-11-26
JP2001525678A (ja) 2001-12-11
EP0983379A1 (de) 2000-03-08
WO1998053098A1 (de) 1998-11-26

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired