AU724421B2 - Covalent polar lipid conjugates with biologically-active compounds for use in salves - Google Patents

Covalent polar lipid conjugates with biologically-active compounds for use in salves Download PDF

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Publication number
AU724421B2
AU724421B2 AU65945/96A AU6594596A AU724421B2 AU 724421 B2 AU724421 B2 AU 724421B2 AU 65945/96 A AU65945/96 A AU 65945/96A AU 6594596 A AU6594596 A AU 6594596A AU 724421 B2 AU724421 B2 AU 724421B2
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AU
Australia
Prior art keywords
composition according
pharmaceutical composition
drug
topically
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU65945/96A
Other languages
English (en)
Other versions
AU6594596A (en
Inventor
Michael H. B Stowell
Milton B Yatvin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oregon Health Science University
Original Assignee
Oregon Health Science University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon Health Science University filed Critical Oregon Health Science University
Publication of AU6594596A publication Critical patent/AU6594596A/en
Application granted granted Critical
Publication of AU724421B2 publication Critical patent/AU724421B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU65945/96A 1996-07-23 1996-07-23 Covalent polar lipid conjugates with biologically-active compounds for use in salves Ceased AU724421B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/012124 WO1998003204A1 (fr) 1996-07-23 1996-07-23 Conjugues lipidiques polaires covalents associes a des composes biologiquement actifs utilisables dans les onguents

Publications (2)

Publication Number Publication Date
AU6594596A AU6594596A (en) 1998-02-10
AU724421B2 true AU724421B2 (en) 2000-09-21

Family

ID=22255500

Family Applications (1)

Application Number Title Priority Date Filing Date
AU65945/96A Ceased AU724421B2 (en) 1996-07-23 1996-07-23 Covalent polar lipid conjugates with biologically-active compounds for use in salves

Country Status (5)

Country Link
EP (1) EP0917473A1 (fr)
JP (1) JPH11514009A (fr)
AU (1) AU724421B2 (fr)
CA (1) CA2261887C (fr)
WO (1) WO1998003204A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000033883A1 (fr) * 1998-12-04 2000-06-15 Oregon Health Sciences University Conjugues lipides polaires covalents avec medicaments antimicrobiens et antineoplasiques destines a cibler des sites biologiques proteges
US6464992B2 (en) * 2000-04-14 2002-10-15 University Of Kentucky Research Foundation Topical micronutrient delivery system and uses thereof
US7045543B2 (en) 2001-11-05 2006-05-16 Enzrel Inc. Covalent conjugates of biologically-active compounds with amino acids and amino acid derivatives for targeting to physiologically-protected sites
CN103857440B (zh) * 2011-06-22 2018-09-25 维奥姆生物科学有限公司 基于缀合物的抗真菌和抗细菌前药
WO2024083171A1 (fr) * 2022-10-20 2024-04-25 苏州艾博生物科技有限公司 Composé lipidique et composition de nanoparticules lipidiques

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991019726A1 (fr) * 1990-06-15 1991-12-26 Wake Forest University Conjugues covalents de lipides d'ether-nucleosides
WO1994001138A1 (fr) * 1992-07-09 1994-01-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Conjugues de lipides/peptides polaires covalents pour ciblage biologique
WO1995032002A1 (fr) * 1994-05-19 1995-11-30 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Conjugues covalents de microparticules et de medicaments pour ciblage biologique

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US5149794A (en) * 1990-11-01 1992-09-22 State Of Oregon Covalent lipid-drug conjugates for drug targeting

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991019726A1 (fr) * 1990-06-15 1991-12-26 Wake Forest University Conjugues covalents de lipides d'ether-nucleosides
WO1994001138A1 (fr) * 1992-07-09 1994-01-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Conjugues de lipides/peptides polaires covalents pour ciblage biologique
WO1995032002A1 (fr) * 1994-05-19 1995-11-30 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Conjugues covalents de microparticules et de medicaments pour ciblage biologique

Also Published As

Publication number Publication date
AU6594596A (en) 1998-02-10
CA2261887A1 (fr) 1998-01-29
JPH11514009A (ja) 1999-11-30
EP0917473A1 (fr) 1999-05-26
CA2261887C (fr) 2007-10-02
WO1998003204A1 (fr) 1998-01-29

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