AU720100B2 - Cyclic peptides having broad spectrum antimicrobial activity - Google Patents

Cyclic peptides having broad spectrum antimicrobial activity Download PDF

Info

Publication number
AU720100B2
AU720100B2 AU39630/97A AU3963097A AU720100B2 AU 720100 B2 AU720100 B2 AU 720100B2 AU 39630/97 A AU39630/97 A AU 39630/97A AU 3963097 A AU3963097 A AU 3963097A AU 720100 B2 AU720100 B2 AU 720100B2
Authority
AU
Australia
Prior art keywords
seq
cyclo
amino acid
peptide
information
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU39630/97A
Other languages
English (en)
Other versions
AU3963097A (en
Inventor
Conway Chang
Jie Chen
Leo Gu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ardea Biociences Inc
Original Assignee
IntraBiotics Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IntraBiotics Pharmaceuticals Inc filed Critical IntraBiotics Pharmaceuticals Inc
Publication of AU3963097A publication Critical patent/AU3963097A/en
Application granted granted Critical
Publication of AU720100B2 publication Critical patent/AU720100B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU39630/97A 1996-07-24 1997-07-23 Cyclic peptides having broad spectrum antimicrobial activity Ceased AU720100B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/685589 1996-07-24
US08/685,589 US5916872A (en) 1996-07-24 1996-07-24 Cyclic peptides having broad spectrum antimicrobial activity
PCT/US1997/012974 WO1998003192A1 (en) 1996-07-24 1997-07-23 Cyclic peptides having broad spectrum antimicrobial activity

Publications (2)

Publication Number Publication Date
AU3963097A AU3963097A (en) 1998-02-10
AU720100B2 true AU720100B2 (en) 2000-05-25

Family

ID=24752864

Family Applications (1)

Application Number Title Priority Date Filing Date
AU39630/97A Ceased AU720100B2 (en) 1996-07-24 1997-07-23 Cyclic peptides having broad spectrum antimicrobial activity

Country Status (8)

Country Link
US (1) US5916872A (https=)
EP (1) EP0956029B1 (https=)
JP (1) JP2001503020A (https=)
AT (1) ATE286740T1 (https=)
AU (1) AU720100B2 (https=)
CA (1) CA2261797A1 (https=)
DE (1) DE69732250D1 (https=)
WO (1) WO1998003192A1 (https=)

Families Citing this family (36)

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US6495518B1 (en) 1994-06-13 2002-12-17 Vanderbilt University Method for importing biologically active molecules into cells
US7553929B2 (en) * 1994-06-13 2009-06-30 Vanderbilt University Cell permeable peptides for inhibition of inflammatory reactions and methods of use
US6307016B1 (en) 1995-07-06 2001-10-23 Intrabiotics Pharmaceuticals, Inc. Parevins and tachytegrins
USRE38828E1 (en) * 1995-07-06 2005-10-11 Intrabiotics Pharmaceuticals, Inc. Parevins and tachytegrins
US6043220A (en) * 1997-12-03 2000-03-28 Intrabiotics Pharmaceuticals, Inc. Threonine-containing protegrins
NZ506839A (en) 1998-03-09 2003-05-30 Zealand Pharma As Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
CA2366678A1 (en) * 1999-03-09 2000-09-14 Fornix Biosciences N.V. Synthetic complementary peptides and ophthalmologic uses thereof
US6335318B1 (en) 1999-05-10 2002-01-01 The Regents Of The University Of California Antimicrobial theta defensins and methods of using same
US7449544B2 (en) * 1999-11-30 2008-11-11 Cyclacel Limited p21 peptides
US6337317B1 (en) * 2000-06-27 2002-01-08 The University Of British Columbia Antimicrobial peptides and methods of use thereof
AU2002247724B2 (en) * 2001-02-23 2008-02-07 Polyphor Ltd. Template-fixed peptidomimetics with antimicrobial activity
US6713078B2 (en) 2001-04-18 2004-03-30 The Regents Of The University Of California Retrocyclins: antiviral and antimicrobial peptides
US7314858B2 (en) 2001-04-18 2008-01-01 The Regents Of The University Of California Retrocyclins: antiviral and antimicrobial peptides
US7119070B2 (en) * 2002-04-30 2006-10-10 The Regents Of The University Of California Antimicrobial theta defensins, analogs thereof, and methods of use
AU2003247435A1 (en) * 2002-05-30 2003-12-19 European Molecular Biology Laboratory Combinatorial chemical library ii
AU2003273578A1 (en) * 2002-05-30 2003-12-19 European Molecular Biology Laboratory Combinatorial chemical library i
US8518694B2 (en) 2002-06-13 2013-08-27 Novartis Vaccines And Diagnostics, Inc. Nucleic acid vector comprising a promoter and a sequence encoding a polypeptide from the endogenous retrovirus PCAV
EP1532164B1 (en) 2002-08-20 2012-09-26 Polyphor Ltd. Template-fixed peptidomimetics with antibacterial activity
WO2004067032A2 (en) * 2003-01-24 2004-08-12 University Of Massachusetts Medical Center Identification of gene sequences and proteins involved in vaccinia virus dominant t cell epitopes
US8067535B2 (en) 2003-01-24 2011-11-29 The University Of Massachusetts Identification of gene sequences and proteins involved in vaccinia virus dominant T cell epitopes
US7538084B2 (en) 2003-03-17 2009-05-26 Amr Technology, Inc. Cyclosporins
JP2008514702A (ja) 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド 新規シクロスポリン類似体およびそれらの薬学的使用
JP2008514701A (ja) 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
JP2008515886A (ja) 2004-10-06 2008-05-15 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキンおよびそれらの医用薬剤としての有用性
US20080255052A1 (en) * 2004-12-23 2008-10-16 The Regents Of The University Of California Immunologic regulation by theta defensins
CA2610791C (en) * 2005-06-08 2015-12-01 Cangene Corporation Hyaluronic acid binding peptides enhance host defense against pathogenic bacteria
PT2236608T (pt) * 2005-10-04 2017-03-01 Soligenix Inc Péptidos novos para tratar e prevenir distúrbios relacionados com a imunidade, incluindo tratar e prevenir infecção por modulação da imunidade inata
AU2012203804B2 (en) * 2005-12-22 2014-10-16 Novabiotics Limited Cyclic antimicrobial peptides
US9181303B2 (en) * 2005-12-22 2015-11-10 Novabiotics Limited Treatment of bacterial infections with cyclic antimicrobial peptides
KR101413746B1 (ko) * 2005-12-22 2014-07-01 노바바이오틱스 리미티드 고리형 항균 펩타이드
WO2007079597A1 (en) 2006-01-16 2007-07-19 Polyphor Ltd. Template - fixed peptidomimetics with antimicrobial activity
SG175573A1 (en) * 2006-10-04 2011-11-28 Inimex Pharmaceuticals Inc Novel peptides for treating and preventing immune-related disorders, including treating and preventing infection by modulating innate immunity
FR2943345B1 (fr) * 2009-03-19 2011-05-27 Univ Paris Curie Analogues de la temporine-sha et leurs utilisations
EP2853538A1 (en) 2013-09-27 2015-04-01 Université Pierre et Marie Curie (Paris 6) Analogues of temporin-SHa and uses thereof
KR20220042129A (ko) * 2019-06-26 2022-04-04 마이클 이. 셀스테드 신규한 세타 디펜신 유사체(novel theta defensin analogs)
JP2023117892A (ja) * 2022-02-14 2023-08-24 公益財団法人 鷹揚郷 ヘプシジン結合ペプチド

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4543252A (en) * 1982-01-21 1985-09-24 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4652639A (en) * 1982-05-06 1987-03-24 Amgen Manufacture and expression of structural genes
US4659692A (en) * 1982-11-19 1987-04-21 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4705777A (en) * 1985-02-25 1987-11-10 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US5126257A (en) * 1986-11-26 1992-06-30 Cornell Research Foundation Antimicrobial proteins, compositions containing same and uses thereof
US5338724A (en) * 1986-11-26 1994-08-16 Cornell Research Foundation, Inc. Antimicrobial proteins, compositions containing same and uses thereof
US5087569A (en) * 1986-11-26 1992-02-11 Cornell Research Foundation, Inc. And The Rockefeller University Antimicrobial proteins, compositions containing same and uses thereof
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides
US5032574A (en) * 1988-05-26 1991-07-16 Invitron Corporation Novel antimicrobial peptide
US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
US5171739A (en) * 1989-02-14 1992-12-15 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and preventation thereof using a BPI protein
US5308834A (en) * 1989-02-14 1994-05-03 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and prevention thereof using a BPI protein
US5334584A (en) * 1989-02-14 1994-08-02 Incyte Pharamaceuticals, Inc. Recombinant, non-glycosylated bpi protein and uses thereof
US5708154A (en) * 1989-02-24 1998-01-13 City Of Hope RNA-DNA hybrid molecules of nucleic acid
US5484885A (en) * 1989-07-05 1996-01-16 Emory University Chemotactic, antibiotic and lipopolysaccharide-binding peptide fragments of CAP37
US5447914A (en) * 1990-06-21 1995-09-05 Emory University Antimicrobial peptides
US5432270A (en) * 1990-10-25 1995-07-11 Zasloff; Michael A. DNA encoding tracheal antimicrobial peptides
US5488035A (en) * 1991-12-06 1996-01-30 Pioneer Hi-Bred International, Inc. Peptide with inhibitory activity towards plant pathogenic fungi
WO1993024139A1 (en) * 1992-05-26 1993-12-09 The Regents Of The University Of California Antibiotic cryptdin peptides and methods of their use
US5422424A (en) * 1992-05-26 1995-06-06 The Regents Of The University Of California Antibiotic cryptdin peptides and methods of their use
US5459235A (en) * 1993-03-19 1995-10-17 The Regents Of The University Of California Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
US5708145A (en) * 1993-07-20 1998-01-13 University Of California Immunglobulins reactive with protegrins
US5464823A (en) * 1993-07-20 1995-11-07 The Regents Of The University Of California Mammalian antibiotic peptides
US5693486A (en) * 1993-07-20 1997-12-02 Intrabiotics DNA sequences encoding protegrins and protegrin analogs and their use in recombinant methods of producing protegrins
US5804558A (en) * 1993-07-20 1998-09-08 University Of California Protegrins
JPH08504837A (ja) * 1993-10-14 1996-05-28 生化学工業株式会社 新規ポリペプチドおよびこれから調製される抗hiv剤
US5635594A (en) * 1994-03-11 1997-06-03 University Of California, Los Angeles Gallinacins - antibiotic peptides

Also Published As

Publication number Publication date
US5916872A (en) 1999-06-29
EP0956029A1 (en) 1999-11-17
CA2261797A1 (en) 1998-01-29
DE69732250D1 (de) 2005-02-17
ATE286740T1 (de) 2005-01-15
AU3963097A (en) 1998-02-10
EP0956029A4 (en) 2001-09-05
JP2001503020A (ja) 2001-03-06
WO1998003192A1 (en) 1998-01-29
EP0956029B1 (en) 2005-01-12

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