ATE286740T1 - Zyklische peptide mit breitspektrum antimikrobieller aktivität - Google Patents

Zyklische peptide mit breitspektrum antimikrobieller aktivität

Info

Publication number
ATE286740T1
ATE286740T1 AT97937009T AT97937009T ATE286740T1 AT E286740 T1 ATE286740 T1 AT E286740T1 AT 97937009 T AT97937009 T AT 97937009T AT 97937009 T AT97937009 T AT 97937009T AT E286740 T1 ATE286740 T1 AT E286740T1
Authority
AT
Austria
Prior art keywords
antimicrobial activity
broad spectrum
cyclic peptides
spectrum antimicrobial
peptides
Prior art date
Application number
AT97937009T
Other languages
German (de)
English (en)
Inventor
Conway Chang
Leo Gu
Jie Chen
Original Assignee
Intrabiotics Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intrabiotics Pharmaceuticals filed Critical Intrabiotics Pharmaceuticals
Application granted granted Critical
Publication of ATE286740T1 publication Critical patent/ATE286740T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97937009T 1996-07-24 1997-07-23 Zyklische peptide mit breitspektrum antimikrobieller aktivität ATE286740T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/685,589 US5916872A (en) 1996-07-24 1996-07-24 Cyclic peptides having broad spectrum antimicrobial activity
PCT/US1997/012974 WO1998003192A1 (en) 1996-07-24 1997-07-23 Cyclic peptides having broad spectrum antimicrobial activity

Publications (1)

Publication Number Publication Date
ATE286740T1 true ATE286740T1 (de) 2005-01-15

Family

ID=24752864

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97937009T ATE286740T1 (de) 1996-07-24 1997-07-23 Zyklische peptide mit breitspektrum antimikrobieller aktivität

Country Status (8)

Country Link
US (1) US5916872A (https=)
EP (1) EP0956029B1 (https=)
JP (1) JP2001503020A (https=)
AT (1) ATE286740T1 (https=)
AU (1) AU720100B2 (https=)
CA (1) CA2261797A1 (https=)
DE (1) DE69732250D1 (https=)
WO (1) WO1998003192A1 (https=)

Families Citing this family (36)

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US7553929B2 (en) * 1994-06-13 2009-06-30 Vanderbilt University Cell permeable peptides for inhibition of inflammatory reactions and methods of use
US6495518B1 (en) 1994-06-13 2002-12-17 Vanderbilt University Method for importing biologically active molecules into cells
US6307016B1 (en) 1995-07-06 2001-10-23 Intrabiotics Pharmaceuticals, Inc. Parevins and tachytegrins
USRE38828E1 (en) * 1995-07-06 2005-10-11 Intrabiotics Pharmaceuticals, Inc. Parevins and tachytegrins
US6043220A (en) * 1997-12-03 2000-03-28 Intrabiotics Pharmaceuticals, Inc. Threonine-containing protegrins
JP4394279B2 (ja) * 1998-03-09 2010-01-06 ジーランド ファーマ アクティーゼルスカブ 酵素加水分解に対する傾向が減少した薬理学的に活性なペプチド複合体
US6310041B1 (en) * 1999-03-09 2001-10-30 Fornix Biosciences N.V. Synthetic complementary peptides and ophthalmologic uses thereof
US6335318B1 (en) 1999-05-10 2002-01-01 The Regents Of The University Of California Antimicrobial theta defensins and methods of using same
US7449544B2 (en) * 1999-11-30 2008-11-11 Cyclacel Limited p21 peptides
US6337317B1 (en) * 2000-06-27 2002-01-08 The University Of British Columbia Antimicrobial peptides and methods of use thereof
ES2527339T3 (es) * 2001-02-23 2015-01-23 Polyphor Ltd. Peptidomiméticos fijados a patrón con actividad antimicrobiana
US7314858B2 (en) 2001-04-18 2008-01-01 The Regents Of The University Of California Retrocyclins: antiviral and antimicrobial peptides
US6713078B2 (en) 2001-04-18 2004-03-30 The Regents Of The University Of California Retrocyclins: antiviral and antimicrobial peptides
US7119070B2 (en) * 2002-04-30 2006-10-10 The Regents Of The University Of California Antimicrobial theta defensins, analogs thereof, and methods of use
AU2003247435A1 (en) * 2002-05-30 2003-12-19 European Molecular Biology Laboratory Combinatorial chemical library ii
WO2003102024A1 (en) * 2002-05-30 2003-12-11 European Molecular Biology Laboratory Combinatorial chemical library i
JP2005535308A (ja) 2002-06-13 2005-11-24 カイロン コーポレイション Ｈｍｌ−２ポリペプチド発現用ベクター
JP4221368B2 (ja) 2002-08-20 2009-02-12 ポリファー リミテッド 抗菌活性を有するテンプレート結合ペプチド擬似体
US8067535B2 (en) 2003-01-24 2011-11-29 The University Of Massachusetts Identification of gene sequences and proteins involved in vaccinia virus dominant T cell epitopes
US7217526B2 (en) * 2003-01-24 2007-05-15 University Of Massachusetts Medical School Identification of gene sequences and proteins involved in vaccinia virus dominant T cell epitopes
EP1603512A2 (en) 2003-03-17 2005-12-14 Albany Molecular Research, Inc. Novel cyclosporins
US7378391B2 (en) 2004-09-29 2008-05-27 Amr Technology, Inc. Cyclosporin alkyne analogues and their pharmaceutical uses
WO2006039164A2 (en) 2004-09-29 2006-04-13 Amr Technology, Inc. Novel cyclosporin analogues and their pharmaceutical uses
WO2006041631A2 (en) 2004-10-06 2006-04-20 Amr Technology, Inc. Novel cyclosporin alkynes and their utility as pharmaceutical agents
US20080255052A1 (en) * 2004-12-23 2008-10-16 The Regents Of The University Of California Immunologic regulation by theta defensins
EP1896386B1 (en) * 2005-06-08 2012-09-05 Cangene Corporation Hyaluronic acid binding peptides enhance host defense against pathogenic bacteria
LT2236608T (lt) * 2005-10-04 2017-03-27 Soligenix, Inc. Naujieji peptidai, skirti gydymui ir prevencijai su imunitetu susijusių sutrikimų, įskaitant infekcijų gydymą ir prevenciją, moduliuojant įgimtą imunitetą
CA2655448C (en) 2005-12-22 2016-09-06 Novabiotics Limited Cyclic antimicrobial peptides
AU2012203804B2 (en) * 2005-12-22 2014-10-16 Novabiotics Limited Cyclic antimicrobial peptides
US9181303B2 (en) * 2005-12-22 2015-11-10 Novabiotics Limited Treatment of bacterial infections with cyclic antimicrobial peptides
WO2007079597A1 (en) 2006-01-16 2007-07-19 Polyphor Ltd. Template - fixed peptidomimetics with antimicrobial activity
AU2007304847A1 (en) * 2006-10-04 2008-04-10 Inimex Pharmaceuticals, Inc. Novel peptides for treating and preventing immune-related disorders, including treating and preventing infection by modulating innate immunity
FR2943345B1 (fr) * 2009-03-19 2011-05-27 Univ Paris Curie Analogues de la temporine-sha et leurs utilisations
EP2853538A1 (en) 2013-09-27 2015-04-01 Université Pierre et Marie Curie (Paris 6) Analogues of temporin-SHa and uses thereof
JP2022538854A (ja) * 2019-06-26 2022-09-06 イー． セルステッド、マイケル 新規なシータディフェンシンアナログ
JP2023117892A (ja) * 2022-02-14 2023-08-24 公益財団法人 鷹揚郷 ヘプシジン結合ペプチド

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US4543252A (en) * 1982-01-21 1985-09-24 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4652639A (en) * 1982-05-06 1987-03-24 Amgen Manufacture and expression of structural genes
US4659692A (en) * 1982-11-19 1987-04-21 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4705777A (en) * 1985-02-25 1987-11-10 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US5087569A (en) * 1986-11-26 1992-02-11 Cornell Research Foundation, Inc. And The Rockefeller University Antimicrobial proteins, compositions containing same and uses thereof
US5126257A (en) * 1986-11-26 1992-06-30 Cornell Research Foundation Antimicrobial proteins, compositions containing same and uses thereof
US5338724A (en) * 1986-11-26 1994-08-16 Cornell Research Foundation, Inc. Antimicrobial proteins, compositions containing same and uses thereof
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides
US5032574A (en) * 1988-05-26 1991-07-16 Invitron Corporation Novel antimicrobial peptide
US5171739A (en) * 1989-02-14 1992-12-15 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and preventation thereof using a BPI protein
US5334584A (en) * 1989-02-14 1994-08-02 Incyte Pharamaceuticals, Inc. Recombinant, non-glycosylated bpi protein and uses thereof
US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
US5308834A (en) * 1989-02-14 1994-05-03 Incyte Pharmaceuticals, Inc. Treatment of endotoxin-associated shock and prevention thereof using a BPI protein
US5708154A (en) * 1989-02-24 1998-01-13 City Of Hope RNA-DNA hybrid molecules of nucleic acid
US5484885A (en) * 1989-07-05 1996-01-16 Emory University Chemotactic, antibiotic and lipopolysaccharide-binding peptide fragments of CAP37
US5447914A (en) * 1990-06-21 1995-09-05 Emory University Antimicrobial peptides
US5432270A (en) * 1990-10-25 1995-07-11 Zasloff; Michael A. DNA encoding tracheal antimicrobial peptides
US5488035A (en) * 1991-12-06 1996-01-30 Pioneer Hi-Bred International, Inc. Peptide with inhibitory activity towards plant pathogenic fungi
ES2152253T3 (es) * 1992-05-26 2001-02-01 Univ California Peptidos de criptdina antibioticos y metodos para su uso.
US5422424A (en) * 1992-05-26 1995-06-06 The Regents Of The University Of California Antibiotic cryptdin peptides and methods of their use
US5459235A (en) * 1993-03-19 1995-10-17 The Regents Of The University Of California Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
US5693486A (en) * 1993-07-20 1997-12-02 Intrabiotics DNA sequences encoding protegrins and protegrin analogs and their use in recombinant methods of producing protegrins
US5708145A (en) * 1993-07-20 1998-01-13 University Of California Immunglobulins reactive with protegrins
US5464823A (en) * 1993-07-20 1995-11-07 The Regents Of The University Of California Mammalian antibiotic peptides
US5804558A (en) * 1993-07-20 1998-09-08 University Of California Protegrins
CN1038841C (zh) * 1993-10-14 1998-06-24 生化学工业株式会社 新型多肽以及由其制备的抗人类免疫缺陷病毒制剂
US5635594A (en) * 1994-03-11 1997-06-03 University Of California, Los Angeles Gallinacins - antibiotic peptides

Also Published As

Publication number Publication date
US5916872A (en) 1999-06-29
EP0956029A1 (en) 1999-11-17
CA2261797A1 (en) 1998-01-29
AU3963097A (en) 1998-02-10
WO1998003192A1 (en) 1998-01-29
EP0956029A4 (en) 2001-09-05
AU720100B2 (en) 2000-05-25
DE69732250D1 (de) 2005-02-17
JP2001503020A (ja) 2001-03-06
EP0956029B1 (en) 2005-01-12

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