AU714602B2 - Animal feed additives - Google Patents
Animal feed additives Download PDFInfo
- Publication number
- AU714602B2 AU714602B2 AU72797/96A AU7279796A AU714602B2 AU 714602 B2 AU714602 B2 AU 714602B2 AU 72797/96 A AU72797/96 A AU 72797/96A AU 7279796 A AU7279796 A AU 7279796A AU 714602 B2 AU714602 B2 AU 714602B2
- Authority
- AU
- Australia
- Prior art keywords
- feed
- galactanase
- endo
- animal feed
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 235000019730 animal feed additive Nutrition 0.000 title claims abstract description 44
- 102000004190 Enzymes Human genes 0.000 claims abstract description 60
- 108090000790 Enzymes Proteins 0.000 claims abstract description 60
- 101710152845 Arabinogalactan endo-beta-1,4-galactanase Proteins 0.000 claims abstract description 36
- 101710147028 Endo-beta-1,4-galactanase Proteins 0.000 claims abstract description 36
- 241001465754 Metazoa Species 0.000 claims description 59
- 229940088598 enzyme Drugs 0.000 claims description 57
- 238000000034 method Methods 0.000 claims description 52
- 108010005774 beta-Galactosidase Proteins 0.000 claims description 27
- 108010059881 Lactase Proteins 0.000 claims description 22
- 102100026189 Beta-galactosidase Human genes 0.000 claims description 21
- 229940116108 lactase Drugs 0.000 claims description 21
- 108010011619 6-Phytase Proteins 0.000 claims description 13
- 235000019621 digestibility Nutrition 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 11
- 238000002203 pretreatment Methods 0.000 claims description 11
- 238000002360 preparation method Methods 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 229940085127 phytase Drugs 0.000 claims description 5
- 239000002002 slurry Substances 0.000 claims description 5
- 239000000969 carrier Substances 0.000 claims description 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 4
- 102000005936 beta-Galactosidase Human genes 0.000 claims 5
- 101710130006 Beta-glucanase Proteins 0.000 claims 3
- 108010001817 Endo-1,4-beta Xylanases Proteins 0.000 claims 3
- 108010030291 alpha-Galactosidase Proteins 0.000 claims 3
- 102000005840 alpha-Galactosidase Human genes 0.000 claims 3
- SATHPVQTSSUFFW-UHFFFAOYSA-N 4-[6-[(3,5-dihydroxy-4-methoxyoxan-2-yl)oxymethyl]-3,5-dihydroxy-4-methoxyoxan-2-yl]oxy-2-(hydroxymethyl)-6-methyloxane-3,5-diol Chemical compound OC1C(OC)C(O)COC1OCC1C(O)C(OC)C(O)C(OC2C(C(CO)OC(C)C2O)O)O1 SATHPVQTSSUFFW-UHFFFAOYSA-N 0.000 abstract description 9
- 229920000189 Arabinogalactan Polymers 0.000 abstract description 9
- 239000001904 Arabinogalactan Substances 0.000 abstract description 9
- 235000019312 arabinogalactan Nutrition 0.000 abstract description 9
- 108010076955 arabinogalactan endo-1,4-beta-galactosidase Proteins 0.000 abstract 1
- 238000002474 experimental method Methods 0.000 description 15
- 235000005911 diet Nutrition 0.000 description 13
- 230000037213 diet Effects 0.000 description 12
- 230000002708 enhancing effect Effects 0.000 description 10
- 210000003608 fece Anatomy 0.000 description 10
- 241000287828 Gallus gallus Species 0.000 description 9
- 239000000047 product Substances 0.000 description 8
- 241000228212 Aspergillus Species 0.000 description 7
- 150000004676 glycans Chemical class 0.000 description 7
- 241000193830 Bacillus <bacterium> Species 0.000 description 6
- -1 P-glucanases Proteins 0.000 description 6
- 235000014590 basal diet Nutrition 0.000 description 6
- 229930182830 galactose Natural products 0.000 description 6
- 239000002609 medium Substances 0.000 description 6
- 229920001282 polysaccharide Polymers 0.000 description 6
- 239000005017 polysaccharide Substances 0.000 description 6
- 241000271566 Aves Species 0.000 description 5
- 241000233866 Fungi Species 0.000 description 5
- 230000015556 catabolic process Effects 0.000 description 5
- 235000013339 cereals Nutrition 0.000 description 5
- 235000013330 chicken meat Nutrition 0.000 description 5
- 238000006731 degradation reaction Methods 0.000 description 5
- 241000228215 Aspergillus aculeatus Species 0.000 description 4
- 241000228245 Aspergillus niger Species 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 108010093031 Galactosidases Proteins 0.000 description 4
- 102000002464 Galactosidases Human genes 0.000 description 4
- 241000223198 Humicola Species 0.000 description 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 4
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 4
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 4
- 235000019764 Soybean Meal Nutrition 0.000 description 4
- 244000144977 poultry Species 0.000 description 4
- 235000013594 poultry meat Nutrition 0.000 description 4
- 239000004455 soybean meal Substances 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 241000235349 Ascomycota Species 0.000 description 3
- 240000006439 Aspergillus oryzae Species 0.000 description 3
- 235000002247 Aspergillus oryzae Nutrition 0.000 description 3
- 244000063299 Bacillus subtilis Species 0.000 description 3
- 235000014469 Bacillus subtilis Nutrition 0.000 description 3
- 101710121765 Endo-1,4-beta-xylanase Proteins 0.000 description 3
- 235000010469 Glycine max Nutrition 0.000 description 3
- 241000221775 Hypocreales Species 0.000 description 3
- 241000219745 Lupinus Species 0.000 description 3
- 241000226677 Myceliophthora Species 0.000 description 3
- 241000235070 Saccharomyces Species 0.000 description 3
- 240000006394 Sorghum bicolor Species 0.000 description 3
- 241000223257 Thermomyces Species 0.000 description 3
- 241000223258 Thermomyces lanuginosus Species 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000002538 fungal effect Effects 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- 241000228195 Aspergillus ficuum Species 0.000 description 2
- 241000221198 Basidiomycota Species 0.000 description 2
- 241000219310 Beta vulgaris subsp. vulgaris Species 0.000 description 2
- 241001489107 Cantharellales Species 0.000 description 2
- 108020004414 DNA Proteins 0.000 description 2
- 241000221785 Erysiphales Species 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 244000068988 Glycine max Species 0.000 description 2
- 241001480714 Humicola insolens Species 0.000 description 2
- 241000123315 Meripilus Species 0.000 description 2
- 108091028043 Nucleic acid sequence Proteins 0.000 description 2
- 241000228143 Penicillium Species 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
- 244000046052 Phaseolus vulgaris Species 0.000 description 2
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 2
- 240000004713 Pisum sativum Species 0.000 description 2
- 235000010582 Pisum sativum Nutrition 0.000 description 2
- 241000222383 Polyporales Species 0.000 description 2
- 239000004365 Protease Substances 0.000 description 2
- 235000019779 Rapeseed Meal Nutrition 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 235000021536 Sugar beet Nutrition 0.000 description 2
- 241000282887 Suidae Species 0.000 description 2
- 235000019772 Sunflower meal Nutrition 0.000 description 2
- 241000223259 Trichoderma Species 0.000 description 2
- 239000006227 byproduct Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- UHZZMRAGKVHANO-UHFFFAOYSA-M chlormequat chloride Chemical compound [Cl-].C[N+](C)(C)CCCl UHZZMRAGKVHANO-UHFFFAOYSA-M 0.000 description 2
- 239000000539 dimer Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 235000021050 feed intake Nutrition 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 239000012634 fragment Substances 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 150000002772 monosaccharides Chemical class 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 239000013600 plasmid vector Substances 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 239000004456 rapeseed meal Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- GUBGYTABKSRVRQ-WWZHPTPQSA-N 4-O-β-D-Galactopyranosyl-D-galactopyranose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-WWZHPTPQSA-N 0.000 description 1
- 241000222485 Agaricales Species 0.000 description 1
- 241000222382 Agaricomycotina Species 0.000 description 1
- 241001513093 Aspergillus awamori Species 0.000 description 1
- 241000351920 Aspergillus nidulans Species 0.000 description 1
- 241001465318 Aspergillus terreus Species 0.000 description 1
- 241000221452 Auriculariales Species 0.000 description 1
- 241000194103 Bacillus pumilus Species 0.000 description 1
- 102100032487 Beta-mannosidase Human genes 0.000 description 1
- 240000002791 Brassica napus Species 0.000 description 1
- 235000004977 Brassica sinapistrum Nutrition 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 108010059892 Cellulase Proteins 0.000 description 1
- 102000005575 Cellulases Human genes 0.000 description 1
- 108010084185 Cellulases Proteins 0.000 description 1
- 241001494491 Chaetomiaceae Species 0.000 description 1
- 241001138366 Dacrymycetales Species 0.000 description 1
- 241000863390 Dictyoglomus Species 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- 241000228427 Eurotiales Species 0.000 description 1
- 244000061944 Helianthus giganteus Species 0.000 description 1
- 238000011993 High Performance Size Exclusion Chromatography Methods 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 102000004157 Hydrolases Human genes 0.000 description 1
- 108090000604 Hydrolases Proteins 0.000 description 1
- 241000123318 Meripilus giganteus Species 0.000 description 1
- 241000221960 Neurospora Species 0.000 description 1
- 241001465194 Onygenales Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 241000286209 Phasianidae Species 0.000 description 1
- 241000222341 Polyporaceae Species 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 108020004511 Recombinant DNA Proteins 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 241000235527 Rhizopus Species 0.000 description 1
- 241001148569 Rhodothermus Species 0.000 description 1
- 241000235342 Saccharomycetes Species 0.000 description 1
- 241001292348 Salipaludibacillus agaradhaerens Species 0.000 description 1
- 241000209056 Secale Species 0.000 description 1
- 235000007238 Secale cereale Nutrition 0.000 description 1
- 241000221926 Sordariales Species 0.000 description 1
- 241000209072 Sorghum Species 0.000 description 1
- 241000187747 Streptomyces Species 0.000 description 1
- 241000204652 Thermotoga Species 0.000 description 1
- 241001136486 Trichocomaceae Species 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000001042 affinity chromatography Methods 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 239000001166 ammonium sulphate Substances 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 239000006053 animal diet Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 108010055059 beta-Mannosidase Proteins 0.000 description 1
- 230000027455 binding Effects 0.000 description 1
- 238000009739 binding Methods 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 150000001720 carbohydrates Chemical group 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 229940106157 cellulase Drugs 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 210000000349 chromosome Anatomy 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 102000038379 digestive enzymes Human genes 0.000 description 1
- 108091007734 digestive enzymes Proteins 0.000 description 1
- 229940079919 digestives enzyme preparation Drugs 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000001641 gel filtration chromatography Methods 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 238000004255 ion exchange chromatography Methods 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 150000004804 polysaccharides Polymers 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000003362 replicative effect Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 102220053233 rs727503091 Human genes 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 239000007974 sodium acetate buffer Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01089—Arabinogalactan endo-beta-1,4-galactanase (3.2.1.89)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/14—Pretreatment of feeding-stuffs with enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01055—Alpha-N-arabinofuranosidase (3.2.1.55)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Animal Husbandry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Biomedical Technology (AREA)
- Fodder In General (AREA)
- Enzymes And Modification Thereof (AREA)
- Feed For Specific Animals (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK123395 | 1995-11-06 | ||
| DK1233/95 | 1995-11-06 | ||
| PCT/DK1996/000443 WO1997016982A1 (en) | 1995-11-06 | 1996-10-22 | Animal feed additives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7279796A AU7279796A (en) | 1997-05-29 |
| AU714602B2 true AU714602B2 (en) | 2000-01-06 |
Family
ID=8102499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU72797/96A Ceased AU714602B2 (en) | 1995-11-06 | 1996-10-22 | Animal feed additives |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6558693B1 (enExample) |
| EP (1) | EP0862371B1 (enExample) |
| JP (1) | JPH11514528A (enExample) |
| KR (1) | KR19990067354A (enExample) |
| CN (1) | CN1201373A (enExample) |
| AT (1) | ATE217153T1 (enExample) |
| AU (1) | AU714602B2 (enExample) |
| BR (1) | BR9611347A (enExample) |
| CA (1) | CA2234607A1 (enExample) |
| DE (1) | DE69621146T2 (enExample) |
| ES (1) | ES2175135T3 (enExample) |
| IN (1) | IN183952B (enExample) |
| WO (1) | WO1997016982A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2535600A (en) * | 1999-02-11 | 2000-08-29 | Novozymes A/S | Bacterial galactanases and use thereof |
| US6855548B2 (en) * | 2000-02-08 | 2005-02-15 | F. Hoffman-La Roche Ag | Use of acid-stable proteases in animal feed |
| US6960462B2 (en) * | 2000-02-08 | 2005-11-01 | Dsm Ip Assets B.V | Use of acid-stable subtilisin proteases in animal feed |
| US7566556B2 (en) * | 2002-03-01 | 2009-07-28 | Academia Sinica | Enhancing enzyme thermostability by mixing with sorghum liquor waste |
| CA2498213C (en) * | 2002-09-10 | 2013-07-16 | Genencor International, Inc. | Induction of gene expression using a high concentration sugar mixture |
| US7537921B2 (en) | 2002-12-20 | 2009-05-26 | Novozymes A/S | Galactanase variants |
| CN102293323A (zh) * | 2005-12-15 | 2011-12-28 | 坎姆根公司 | 用于减少免疫应激的酶 |
| EP2254591B1 (en) | 2008-02-08 | 2017-07-26 | Prothera, Inc. | Inhibition and treatment of gastrointestinal biofilms |
| CN105231024B (zh) * | 2015-09-15 | 2016-12-07 | 上海国龙生物科技有限公司 | 一种用于饲料的复合酶制剂 |
| CN109312321A (zh) * | 2016-05-24 | 2019-02-05 | 诺维信公司 | 包含具有半乳聚糖酶活性的多肽和具有β-半乳糖苷酶活性的多肽的组合物 |
| AU2017270269A1 (en) * | 2016-05-24 | 2018-11-15 | Novozymes A/S | Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity |
| WO2019096903A1 (en) * | 2017-11-20 | 2019-05-23 | Novozymes A/S | New galactanases (ec 3.2.1.89) for use in soy processing |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR950014441B1 (ko) * | 1986-08-28 | 1995-11-28 | 코르텍스 리미티드 | 동물의 장에 생물학적 활성물질을 전달하는데 유용한 미세과립형 제제 |
| EP0498137A1 (en) * | 1991-02-06 | 1992-08-12 | Novo Nordisk A/S | Novel expression systems |
| AU5809594A (en) * | 1992-12-23 | 1994-07-19 | Novo Nordisk A/S | An enzyme with polygalacturonase activity |
-
1996
- 1996-10-22 KR KR1019980703361A patent/KR19990067354A/ko not_active Ceased
- 1996-10-22 CN CN96198103A patent/CN1201373A/zh active Pending
- 1996-10-22 AU AU72797/96A patent/AU714602B2/en not_active Ceased
- 1996-10-22 BR BR9611347A patent/BR9611347A/pt not_active Application Discontinuation
- 1996-10-22 CA CA002234607A patent/CA2234607A1/en not_active Abandoned
- 1996-10-22 AT AT96934447T patent/ATE217153T1/de not_active IP Right Cessation
- 1996-10-22 ES ES96934447T patent/ES2175135T3/es not_active Expired - Lifetime
- 1996-10-22 EP EP96934447A patent/EP0862371B1/en not_active Expired - Lifetime
- 1996-10-22 WO PCT/DK1996/000443 patent/WO1997016982A1/en not_active Ceased
- 1996-10-22 JP JP9517759A patent/JPH11514528A/ja active Pending
- 1996-10-22 DE DE69621146T patent/DE69621146T2/de not_active Expired - Lifetime
- 1996-10-28 IN IN1893MA1996 patent/IN183952B/en unknown
-
1998
- 1998-04-14 US US09/059,771 patent/US6558693B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69621146T2 (de) | 2002-11-28 |
| KR19990067354A (ko) | 1999-08-16 |
| EP0862371B1 (en) | 2002-05-08 |
| ATE217153T1 (de) | 2002-05-15 |
| IN183952B (enExample) | 2000-05-20 |
| JPH11514528A (ja) | 1999-12-14 |
| CN1201373A (zh) | 1998-12-09 |
| BR9611347A (pt) | 1999-03-09 |
| DE69621146D1 (de) | 2002-06-13 |
| WO1997016982A1 (en) | 1997-05-15 |
| US6558693B1 (en) | 2003-05-06 |
| ES2175135T3 (es) | 2002-11-16 |
| EP0862371A1 (en) | 1998-09-09 |
| CA2234607A1 (en) | 1997-05-15 |
| MX9803507A (es) | 1998-09-30 |
| AU7279796A (en) | 1997-05-29 |
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