AU711029B2 - Partitioning device - Google Patents
Partitioning device Download PDFInfo
- Publication number
- AU711029B2 AU711029B2 AU21341/97A AU2134197A AU711029B2 AU 711029 B2 AU711029 B2 AU 711029B2 AU 21341/97 A AU21341/97 A AU 21341/97A AU 2134197 A AU2134197 A AU 2134197A AU 711029 B2 AU711029 B2 AU 711029B2
- Authority
- AU
- Australia
- Prior art keywords
- objects
- detector
- tube
- small
- beads
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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- 239000011324 bead Substances 0.000 claims description 133
- 239000000725 suspension Substances 0.000 claims description 36
- 239000012530 fluid Substances 0.000 claims description 33
- 238000000034 method Methods 0.000 claims description 27
- 239000007787 solid Substances 0.000 claims description 16
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 12
- 239000002245 particle Substances 0.000 claims description 10
- 230000003287 optical effect Effects 0.000 claims description 8
- MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 claims description 6
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 230000005855 radiation Effects 0.000 claims description 5
- 239000004793 Polystyrene Substances 0.000 claims description 4
- 230000009471 action Effects 0.000 claims description 4
- -1 amino, hydroxy, carboxy Chemical group 0.000 claims description 4
- 229920002223 polystyrene Polymers 0.000 claims description 4
- UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 claims description 3
- WHNPOQXWAMXPTA-UHFFFAOYSA-N 3-methylbut-2-enamide Chemical compound CC(C)=CC(N)=O WHNPOQXWAMXPTA-UHFFFAOYSA-N 0.000 claims description 3
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
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- 125000005843 halogen group Chemical group 0.000 claims description 3
- 229920001600 hydrophobic polymer Polymers 0.000 claims description 3
- 239000004816 latex Substances 0.000 claims description 3
- 229920000126 latex Polymers 0.000 claims description 3
- BMMKGFHYBJRLBH-UHFFFAOYSA-N n-(2-aminoethyl)-n-prop-2-enoylprop-2-enamide Chemical compound NCCN(C(=O)C=C)C(=O)C=C BMMKGFHYBJRLBH-UHFFFAOYSA-N 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
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- 238000012986 modification Methods 0.000 description 3
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 2
- 229920000936 Agarose Polymers 0.000 description 2
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- 238000005406 washing Methods 0.000 description 2
- 239000002033 PVDF binder Substances 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
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- 230000003213 activating effect Effects 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
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- 210000000601 blood cell Anatomy 0.000 description 1
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- 238000004140 cleaning Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 239000012611 container material Substances 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
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- 239000006194 liquid suspension Substances 0.000 description 1
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- 230000009972 noncorrosive effect Effects 0.000 description 1
- 230000010355 oscillation Effects 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
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- 230000001960 triggered effect Effects 0.000 description 1
- 239000003039 volatile agent Substances 0.000 description 1
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- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00364—Pipettes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00468—Beads by manipulation of individual beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00479—Means for mixing reactants or products in the reaction vessels
- B01J2219/00484—Means for mixing reactants or products in the reaction vessels by shaking, vibrating or oscillating of the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
- G01N2001/282—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on with mapping; Identification of areas; Spatial correlated pattern
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Paper (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Sampling And Sample Adjustment (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/606,573 US5649576A (en) | 1996-02-26 | 1996-02-26 | Partitioning device |
| US08/606573 | 1996-02-26 | ||
| PCT/US1997/002735 WO1997030897A1 (en) | 1996-02-26 | 1997-02-24 | Partitioning device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2134197A AU2134197A (en) | 1997-09-10 |
| AU711029B2 true AU711029B2 (en) | 1999-10-07 |
Family
ID=24428518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU21341/97A Ceased AU711029B2 (en) | 1996-02-26 | 1997-02-24 | Partitioning device |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5649576A (enExample) |
| EP (1) | EP0956238A1 (enExample) |
| JP (1) | JP2000506057A (enExample) |
| AU (1) | AU711029B2 (enExample) |
| CA (1) | CA2238982A1 (enExample) |
| WO (1) | WO1997030897A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100224655B1 (ko) * | 1995-11-23 | 2000-02-01 | 윤종용 | 현상액 분사 점검시스템 및 이를 이용한 현상액 측정방법 |
| EP0946278A1 (en) | 1996-10-21 | 1999-10-06 | Smithkline Beecham Plc | Apparatus and method for distributing beads |
| JP2001527642A (ja) * | 1997-01-17 | 2001-12-25 | スミスクライン・ビーチャム・コーポレイション | ビーズを配列するための装置および方法 |
| GB9726482D0 (en) * | 1997-12-15 | 1998-02-11 | Kalibrant Limited | Method and apparatus for chemical synthesis |
| US6884626B1 (en) | 1998-04-27 | 2005-04-26 | Corning Incorporated | Redrawn capillary imaging reservoir |
| US6350618B1 (en) | 1998-04-27 | 2002-02-26 | Corning Incorporated | Redrawn capillary imaging reservoir |
| DE69835342T2 (de) * | 1998-04-27 | 2007-08-23 | Corning Inc. | Verfahren zur Ablage von biologischen Proben mit Hilfe eines nachgezogenen Kapillarspeichers |
| WO1999058476A2 (en) * | 1998-05-08 | 1999-11-18 | Chiron Corporation | Method and device for nonsynthetic deconvolution |
| JP2002514832A (ja) * | 1998-05-13 | 2002-05-21 | スペクトラ システムズ コーポレーション | マイクロレーザ光線発生ビーズと構造体及びその方法 |
| EP2360271A1 (en) | 1998-06-24 | 2011-08-24 | Illumina, Inc. | Decoding of array sensors with microspheres |
| US6762061B1 (en) | 1998-07-03 | 2004-07-13 | Corning Incorporated | Redrawn capillary imaging reservoir |
| US7510841B2 (en) * | 1998-12-28 | 2009-03-31 | Illumina, Inc. | Methods of making and using composite arrays for the detection of a plurality of target analytes |
| US6429027B1 (en) | 1998-12-28 | 2002-08-06 | Illumina, Inc. | Composite arrays utilizing microspheres |
| US6151973A (en) * | 1999-01-29 | 2000-11-28 | Glaxo Wellcome Inc. | Bead picking apparatus and method |
| US6432719B1 (en) * | 1999-02-16 | 2002-08-13 | Pe Corporation (Ny) | Matrix storage and dispensing system |
| ATE341003T1 (de) | 1999-02-16 | 2006-10-15 | Applera Corp | Vorrichtung zur handhabung von kügelchen |
| US7101510B2 (en) | 1999-02-16 | 2006-09-05 | Applera Corporation | Matrix storage and dispensing system |
| IL148677A0 (en) * | 1999-09-14 | 2002-09-12 | Pharmacopeia Inc | Article comprising a multi-channel dispensing head |
| US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| US6770441B2 (en) * | 2000-02-10 | 2004-08-03 | Illumina, Inc. | Array compositions and methods of making same |
| DE10236241B4 (de) * | 2002-08-07 | 2005-04-21 | Bavarian Nordic A/S | Abfüllvorrichtung für Kapseln, insbesondere Arzneimittelkapseln |
| CA2513985C (en) | 2003-01-21 | 2012-05-29 | Illumina Inc. | Chemical reaction monitor |
| US20060246576A1 (en) | 2005-04-06 | 2006-11-02 | Affymetrix, Inc. | Fluidic system and method for processing biological microarrays in personal instrumentation |
| US20070258862A1 (en) * | 2006-05-02 | 2007-11-08 | Applera Corporation | Variable volume dispenser and method |
| US7625115B2 (en) * | 2006-06-23 | 2009-12-01 | Exxonmobil Research And Engineering Company | Method of blending lubricants using positive displacement liquid-handling equipment |
| US9523701B2 (en) | 2009-07-29 | 2016-12-20 | Dynex Technologies, Inc. | Sample plate systems and methods |
| GB0913258D0 (en) | 2009-07-29 | 2009-09-02 | Dynex Technologies Inc | Reagent dispenser |
| EP2894459A4 (en) * | 2012-09-06 | 2016-04-27 | Furukawa Electric Co Ltd | APPARATUS FOR IDENTIFICATION AND OUTPUT OF SAMPLES AND METHOD FOR IDENTIFYING AND SUBMITTING SAMPLES |
| EP3376182A1 (en) * | 2017-03-14 | 2018-09-19 | CSEM Centre Suisse D'electronique Et De Microtechnique SA | Fluid dispensing system and method |
| EP4089401B1 (de) * | 2021-05-10 | 2024-11-06 | Siemens Aktiengesellschaft | Messeinrichtung und verfahren zur messung von mindestens zwei verschiedenen komponenten eines fluids mittels ramanstreuung und chemilumineszenz |
| US11820140B2 (en) | 2022-03-21 | 2023-11-21 | Funai Electric Co., Ltd | Dispense modes for multi-mode capable device |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4318480A (en) * | 1979-08-20 | 1982-03-09 | Ortho Diagnostics, Inc. | Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE793185A (fr) * | 1971-12-23 | 1973-04-16 | Atomic Energy Commission | Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques |
| US4009435A (en) * | 1973-10-19 | 1977-02-22 | Coulter Electronics, Inc. | Apparatus for preservation and identification of particles analyzed by flow-through apparatus |
| US4173415A (en) * | 1976-08-20 | 1979-11-06 | Science Spectrum, Inc. | Apparatus and process for rapidly characterizing and differentiating large organic cells |
| US4184766A (en) * | 1976-10-28 | 1980-01-22 | Coulter Electronics, Inc. | Method and apparatus for correlating measurements of tandem sensing zones |
| US4606631A (en) * | 1983-05-12 | 1986-08-19 | Kabushiki Kaisha Toshiba | Particle counter |
| US4538733A (en) * | 1983-10-14 | 1985-09-03 | Becton, Dickinson And Company | Particle sorter with neutralized collection wells and method of using same |
| FR2571135B1 (fr) * | 1984-10-02 | 1987-02-06 | Moet & Chandon | Procede et appareil de transfert et/ou de dosage de particules fragiles, a cadence elevee, en vue, par exemple, de l'insertion dans un recipient |
| US4680977A (en) * | 1985-03-06 | 1987-07-21 | Ivac Corporation | Optical flow sensor |
| US5108926A (en) * | 1987-09-08 | 1992-04-28 | Board Of Regents, The University Of Texas System | Apparatus for the precise positioning of cells |
| JPH03140840A (ja) * | 1989-10-26 | 1991-06-14 | Hitachi Ltd | 流動細胞分析装置 |
| JP2815435B2 (ja) * | 1989-12-22 | 1998-10-27 | 株式会社日立製作所 | 粒子解析装置及び血球カウンタ |
| US5286452A (en) * | 1991-05-20 | 1994-02-15 | Sienna Biotech, Inc. | Simultaneous multiple assays |
| EP0773227A1 (en) * | 1991-09-18 | 1997-05-14 | Affymax Technologies N.V. | Diverse collections of oligomers in use to prepare drugs, diagnostic reagents, pesticides or herbicides |
| JPH08506175A (ja) * | 1992-10-01 | 1996-07-02 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク | タグでコードされる複合体の組合せ化学ライブラリー |
| US5483469A (en) * | 1993-08-02 | 1996-01-09 | The Regents Of The University Of California | Multiple sort flow cytometer |
-
1996
- 1996-02-26 US US08/606,573 patent/US5649576A/en not_active Expired - Fee Related
-
1997
- 1997-02-24 CA CA002238982A patent/CA2238982A1/en not_active Abandoned
- 1997-02-24 EP EP97906722A patent/EP0956238A1/en not_active Withdrawn
- 1997-02-24 AU AU21341/97A patent/AU711029B2/en not_active Ceased
- 1997-02-24 JP JP9530340A patent/JP2000506057A/ja active Pending
- 1997-02-24 WO PCT/US1997/002735 patent/WO1997030897A1/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4318480A (en) * | 1979-08-20 | 1982-03-09 | Ortho Diagnostics, Inc. | Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997030897A1 (en) | 1997-08-28 |
| CA2238982A1 (en) | 1997-08-28 |
| AU2134197A (en) | 1997-09-10 |
| EP0956238A4 (enExample) | 1999-11-17 |
| EP0956238A1 (en) | 1999-11-17 |
| JP2000506057A (ja) | 2000-05-23 |
| US5649576A (en) | 1997-07-22 |
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