AU710876B2 - Quinolones and their therapeutic use - Google Patents

Quinolones and their therapeutic use Download PDF

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Publication number
AU710876B2
AU710876B2 AU18861/97A AU1886197A AU710876B2 AU 710876 B2 AU710876 B2 AU 710876B2 AU 18861/97 A AU18861/97 A AU 18861/97A AU 1886197 A AU1886197 A AU 1886197A AU 710876 B2 AU710876 B2 AU 710876B2
Authority
AU
Australia
Prior art keywords
compound
disease
alkyl
disease state
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU18861/97A
Other languages
English (en)
Other versions
AU1886197A (en
Inventor
Steven Colin Beasley
Alan Findlay Haughan
John Gary Montana
Robert John Watson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Darwin Discovery Ltd
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603689.2A external-priority patent/GB9603689D0/en
Priority claimed from GBGB9603655.3A external-priority patent/GB9603655D0/en
Priority claimed from GBGB9603654.6A external-priority patent/GB9603654D0/en
Priority claimed from GBGB9702929.2A external-priority patent/GB9702929D0/en
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of AU1886197A publication Critical patent/AU1886197A/en
Application granted granted Critical
Publication of AU710876B2 publication Critical patent/AU710876B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU18861/97A 1996-02-21 1997-02-21 Quinolones and their therapeutic use Ceased AU710876B2 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
GB9603689 1996-02-21
GBGB9603689.2A GB9603689D0 (en) 1996-02-21 1996-02-21 Novel compounds
GB9603655 1996-02-21
GB9603654 1996-02-21
GBGB9603655.3A GB9603655D0 (en) 1996-02-21 1996-02-21 Novel compounds
GBGB9603654.6A GB9603654D0 (en) 1996-02-21 1996-02-21 Novel compounds
GB9702929 1997-02-13
GBGB9702929.2A GB9702929D0 (en) 1997-02-13 1997-02-13 Quinolones and their therapeutic use
PCT/GB1997/000492 WO1997031000A1 (en) 1996-02-21 1997-02-21 Quinolones and their therapeutic use

Publications (2)

Publication Number Publication Date
AU1886197A AU1886197A (en) 1997-09-10
AU710876B2 true AU710876B2 (en) 1999-09-30

Family

ID=27451406

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18861/97A Ceased AU710876B2 (en) 1996-02-21 1997-02-21 Quinolones and their therapeutic use

Country Status (5)

Country Link
EP (1) EP0882047A1 (ja)
JP (1) JP2000505451A (ja)
AU (1) AU710876B2 (ja)
CA (1) CA2241891A1 (ja)
WO (1) WO1997031000A1 (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69810651T2 (de) * 1997-10-07 2003-08-21 Boehringer Ingelheim Ca Ltd Azetidinonderivate zur behandlung von hcmv entzündungen
KR100701904B1 (ko) 1999-08-21 2007-04-02 알타나 파마 아게 Ｐｄｅ 억제제 및 베타 2 아드레날린수용체 작동제의상승적 조합
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US6525049B2 (en) * 2000-07-05 2003-02-25 Pharmacia & Upjohn Company Pyrroloquinolones as antiviral agents
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
US6777407B2 (en) 2000-11-03 2004-08-17 Wyeth Cyclopenta[b][1,4]diazepino[6,7,1-hi]indoles and derivatives
AR031199A1 (es) 2000-11-03 2003-09-10 Wyeth Corp Ciclohepta/b//1,4/diacepino/6,7,1-hi/indoles y derivados
AR031200A1 (es) 2000-11-03 2003-09-10 Wyeth Corp Cicloocta [b] [1,4] diazepino [6,7,1-hi] indoles y derivados
GB0030877D0 (en) 2000-12-18 2001-01-31 Unilever Plc Enhancement of air bleaching catalysts
US6821969B2 (en) 2001-02-13 2004-11-23 Pharmacia & Upjohn Company Thioxazinoquinolones as antiviral agents
US6964966B2 (en) * 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
AU2002361493A1 (en) * 2001-12-13 2003-06-23 Wockhardt Limited New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
TW200307540A (en) 2002-04-25 2003-12-16 Wyeth Corp [1, 4]Diazocino[7, 8, 1-hi] indole derivatives as antipsychotic and antiobesity agents
TW200307682A (en) 2002-04-25 2003-12-16 Wyeth Corp 1,2,3,4,7,8-Hexahydro-6H-[1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
TWI312781B (en) 2002-04-25 2009-08-01 [1,4]diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents
WO2003099815A1 (en) 2002-05-28 2003-12-04 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
ATE366734T1 (de) 2003-09-04 2007-08-15 Wockhardt Ltd Benzochinolizin-2-carbonsäureargininsalz- tetrahydrat
GT200500317A (es) 2004-11-05 2006-10-27 Proceso para preparar compuestos de quinolina y productos obtenidos de los mismos
AR054849A1 (es) 2005-07-26 2007-07-18 Wyeth Corp Diazepinoquinolinas, sintesis de las mismas, e intermediarios para obtenerlas
US8178667B2 (en) 2006-06-28 2012-05-15 Merck Sharp & Dohme Corp. Benzyl-substituted quinolone M1 receptor positive allosteric modulators
JP6579549B2 (ja) 2014-05-16 2019-09-25 塩野義製薬株式会社 Ｈｉｖ複製阻害作用を有する３環性複素環誘導体
WO2016194806A1 (ja) 2015-05-29 2016-12-08 塩野義製薬株式会社 Ｈｉｖ複製阻害作用を有する含窒素３環性誘導体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1433151A (en) * 1973-04-05 1976-04-22 Allen & Hanburys Ltd Benzo-ij-quinolizines

Also Published As

Publication number Publication date
EP0882047A1 (en) 1998-12-09
WO1997031000A1 (en) 1997-08-28
CA2241891A1 (en) 1997-08-21
JP2000505451A (ja) 2000-05-09
AU1886197A (en) 1997-09-10

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired