AU676194B2 - Non-native liver generation in an animal with impaired native liver function by cell implantation - Google Patents
Non-native liver generation in an animal with impaired native liver function by cell implantation Download PDFInfo
- Publication number
- AU676194B2 AU676194B2 AU47782/93A AU4778293A AU676194B2 AU 676194 B2 AU676194 B2 AU 676194B2 AU 47782/93 A AU47782/93 A AU 47782/93A AU 4778293 A AU4778293 A AU 4778293A AU 676194 B2 AU676194 B2 AU 676194B2
- Authority
- AU
- Australia
- Prior art keywords
- native
- liver
- cells
- animal
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91805092A | 1992-07-24 | 1992-07-24 | |
US918050 | 1992-07-24 | ||
PCT/US1993/006830 WO1994002601A1 (en) | 1992-07-24 | 1993-07-23 | Non-native liver generation in an animal with impaired native liver function by cell implantation |
Publications (2)
Publication Number | Publication Date |
---|---|
AU4778293A AU4778293A (en) | 1994-02-14 |
AU676194B2 true AU676194B2 (en) | 1997-03-06 |
Family
ID=25439709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU47782/93A Ceased AU676194B2 (en) | 1992-07-24 | 1993-07-23 | Non-native liver generation in an animal with impaired native liver function by cell implantation |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0652949A4 (ja) |
JP (1) | JPH07509363A (ja) |
AU (1) | AU676194B2 (ja) |
CA (1) | CA2140785A1 (ja) |
IL (1) | IL106368A0 (ja) |
WO (1) | WO1994002601A1 (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2157225T3 (es) * | 1992-10-09 | 2001-08-16 | Advanced Tissue Sciences Inc | Celulas hepaticas de reserva. |
US5980886A (en) * | 1994-12-14 | 1999-11-09 | University Of Washington | Recombinant vectors for reconstitution of liver |
US6107027A (en) * | 1994-12-14 | 2000-08-22 | University Of Washington | Ribozymes for treating hepatitis C |
WO1996039810A1 (en) * | 1995-06-07 | 1996-12-19 | Novartis Ag | Human hepatocellular tissue in chimeric immunocompromised animals |
US6034297A (en) * | 1997-09-26 | 2000-03-07 | Cedars-Sinai Medical Center | In vivo, animal model for expression of hepatitis C virus |
US6132708A (en) * | 1997-10-10 | 2000-10-17 | Oregon Health Sciences University | Liver regeneration using pancreas cells |
US6864402B1 (en) | 1998-09-18 | 2005-03-08 | Albert Einstein College Of Medicine Of Yeshiva University | Chronic hepatitis virus infection and clonal hepatocellular carcinoma in mouse repopulated livers |
WO2000040083A1 (en) * | 1999-01-05 | 2000-07-13 | Surrogen, Inc. | Chimeric animal with engrafted xenogeneic tissue and method for producing same |
US6525242B1 (en) | 1999-11-02 | 2003-02-25 | The University Of Connecticut | Propagation of human hepatocytes in non-human mammals |
US6995299B2 (en) | 1999-11-02 | 2006-02-07 | University Of Connecticut | Propagation of human hepatocytes in non-human animals |
US6509514B1 (en) | 2000-03-17 | 2003-01-21 | Kmt Hepatech, Inc. | Chimeric animal model susceptible to human hepatitis C virus infection |
WO2001087059A1 (fr) * | 2000-05-19 | 2001-11-22 | Japan Science And Technology Corporation | Animal chimerique |
US7560279B2 (en) * | 2002-03-25 | 2009-07-14 | Hiroshima Industrial Promotion Organization | Method of proliferating human hepatocytes and method for obtaining human hepatocytes |
WO2004006664A1 (ja) * | 2002-07-16 | 2004-01-22 | Japan Science And Technology Agency | 非癌部肝臓組織が移植されたモデル動物およびその作製方法 |
ATE461448T1 (de) * | 2004-08-20 | 2010-04-15 | Sekisui Medical Co Ltd | Verfahren zur abschätzung des metabolismus eines arzneistoffs in der menschlichen leber sowie der leberfunktion |
AU2005277463A1 (en) | 2004-08-20 | 2006-03-02 | Kmt Hepatech, Inc. | Malarial animal model having a chimeric human liver |
WO2019059158A1 (ja) * | 2017-09-19 | 2019-03-28 | 学校法人明治大学 | 特定の機能細胞を欠損する臓器を発達させる方法 |
-
1993
- 1993-07-16 IL IL106368A patent/IL106368A0/xx unknown
- 1993-07-23 CA CA002140785A patent/CA2140785A1/en not_active Abandoned
- 1993-07-23 EP EP93918276A patent/EP0652949A4/en not_active Withdrawn
- 1993-07-23 AU AU47782/93A patent/AU676194B2/en not_active Ceased
- 1993-07-23 JP JP6504654A patent/JPH07509363A/ja active Pending
- 1993-07-23 WO PCT/US1993/006830 patent/WO1994002601A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU4778293A (en) | 1994-02-14 |
CA2140785A1 (en) | 1994-02-03 |
IL106368A0 (en) | 1993-11-15 |
WO1994002601A1 (en) | 1994-02-03 |
EP0652949A4 (en) | 1996-08-21 |
EP0652949A1 (en) | 1995-05-17 |
JPH07509363A (ja) | 1995-10-19 |
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