AU658887B2 - Pyridazinone acetic acids as aldose reductase inhibitors - Google Patents
Pyridazinone acetic acids as aldose reductase inhibitors Download PDFInfo
- Publication number
- AU658887B2 AU658887B2 AU17796/92A AU1779692A AU658887B2 AU 658887 B2 AU658887 B2 AU 658887B2 AU 17796/92 A AU17796/92 A AU 17796/92A AU 1779692 A AU1779692 A AU 1779692A AU 658887 B2 AU658887 B2 AU 658887B2
- Authority
- AU
- Australia
- Prior art keywords
- methyl
- compound
- hydrogen
- oxo
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67691991A | 1991-03-28 | 1991-03-28 | |
| US676919 | 1991-03-28 | ||
| PCT/US1992/001603 WO1992017446A2 (en) | 1991-03-28 | 1992-03-09 | Pyridazinone acetic acids aldose reductase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU1779692A AU1779692A (en) | 1992-11-02 |
| AU658887B2 true AU658887B2 (en) | 1995-05-04 |
Family
ID=24716565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU17796/92A Ceased AU658887B2 (en) | 1991-03-28 | 1992-03-09 | Pyridazinone acetic acids as aldose reductase inhibitors |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0582643A1 (de) |
| JP (1) | JPH06500793A (de) |
| CN (1) | CN1065269A (de) |
| AU (1) | AU658887B2 (de) |
| BR (1) | BR9205810A (de) |
| CA (1) | CA2107104A1 (de) |
| CZ (1) | CZ387092A3 (de) |
| DE (1) | DE9290035U1 (de) |
| FI (1) | FI934222A0 (de) |
| HU (1) | HUT67836A (de) |
| IE (1) | IE920979A1 (de) |
| IL (1) | IL101325A0 (de) |
| MX (1) | MX9201414A (de) |
| NZ (1) | NZ242152A (de) |
| PT (1) | PT100301A (de) |
| TW (1) | TW207998B (de) |
| WO (1) | WO1992017446A2 (de) |
| YU (1) | YU30392A (de) |
| ZA (1) | ZA922238B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE297902T1 (de) | 2001-02-28 | 2005-07-15 | Pfizer Prod Inc | Sulfonyl-pyridazinon-derivate zur verwendung als aldose-reduktase-inhibitoren |
| SE0100873D0 (sv) * | 2001-03-13 | 2001-03-13 | Astrazeneca Ab | Method of treatment |
| PT1373259E (pt) | 2001-03-30 | 2005-03-31 | Pfizer Prod Inc | Inibidores piridazinona de aldose reductase |
| AU761191B2 (en) * | 2001-05-24 | 2003-05-29 | Pfizer Products Inc. | Therapies for tissue damage resulting from ischemia |
| US7572910B2 (en) | 2003-02-20 | 2009-08-11 | Pfizer, Inc. | Pyridazinone aldose reductase inhibitors |
| CN111617072B (zh) * | 2019-02-27 | 2023-06-20 | 苏州凯祥生物科技有限公司 | 一种高尿酸血症药物组合物及用于治疗高尿酸血症的药物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0676391B2 (ja) * | 1987-06-09 | 1994-09-28 | フアイザー・インコーポレイテツド | ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法 |
| FR2647676A1 (fr) * | 1989-06-05 | 1990-12-07 | Union Pharma Scient Appl | Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase |
-
1992
- 1992-03-09 BR BR9205810A patent/BR9205810A/pt not_active Application Discontinuation
- 1992-03-09 CA CA002107104A patent/CA2107104A1/en not_active Abandoned
- 1992-03-09 DE DE9290035U patent/DE9290035U1/de not_active Expired - Lifetime
- 1992-03-09 HU HU9302728A patent/HUT67836A/hu unknown
- 1992-03-09 CZ CS923870A patent/CZ387092A3/cs unknown
- 1992-03-09 EP EP92910955A patent/EP0582643A1/de not_active Withdrawn
- 1992-03-09 AU AU17796/92A patent/AU658887B2/en not_active Ceased
- 1992-03-09 JP JP4509938A patent/JPH06500793A/ja active Pending
- 1992-03-09 WO PCT/US1992/001603 patent/WO1992017446A2/en not_active Application Discontinuation
- 1992-03-13 TW TW081101914A patent/TW207998B/zh active
- 1992-03-22 IL IL101325A patent/IL101325A0/xx unknown
- 1992-03-26 PT PT100301A patent/PT100301A/pt not_active Application Discontinuation
- 1992-03-26 YU YU30392A patent/YU30392A/sh unknown
- 1992-03-27 IE IE097992A patent/IE920979A1/en not_active Application Discontinuation
- 1992-03-27 MX MX9201414A patent/MX9201414A/es unknown
- 1992-03-27 ZA ZA922238A patent/ZA922238B/xx unknown
- 1992-03-27 NZ NZ24215292A patent/NZ242152A/en unknown
- 1992-03-27 CN CN92102224A patent/CN1065269A/zh active Pending
-
1993
- 1993-09-27 FI FI934222A patent/FI934222A0/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TW207998B (de) | 1993-06-21 |
| CZ387092A3 (en) | 1994-02-16 |
| FI934222A (fi) | 1993-09-27 |
| HUT67836A (en) | 1995-05-29 |
| ZA922238B (en) | 1993-09-27 |
| YU30392A (sh) | 1994-11-15 |
| AU1779692A (en) | 1992-11-02 |
| DE9290035U1 (de) | 1993-11-18 |
| JPH06500793A (ja) | 1994-01-27 |
| WO1992017446A3 (en) | 1992-11-26 |
| IL101325A0 (en) | 1992-11-15 |
| BR9205810A (pt) | 1994-06-28 |
| FI934222A0 (fi) | 1993-09-27 |
| NZ242152A (en) | 1994-07-26 |
| PT100301A (pt) | 1993-06-30 |
| CA2107104A1 (en) | 1992-09-29 |
| WO1992017446A2 (en) | 1992-10-15 |
| IE920979A1 (en) | 1992-10-07 |
| HU9302728D0 (en) | 1993-12-28 |
| CN1065269A (zh) | 1992-10-14 |
| EP0582643A1 (de) | 1994-02-16 |
| MX9201414A (es) | 1992-10-01 |
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