AU652939B2 - Targeted protection from cytotoxins - Google Patents
Targeted protection from cytotoxinsInfo
- Publication number
- AU652939B2 AU652939B2 AU79026/91A AU7902691A AU652939B2 AU 652939 B2 AU652939 B2 AU 652939B2 AU 79026/91 A AU79026/91 A AU 79026/91A AU 7902691 A AU7902691 A AU 7902691A AU 652939 B2 AU652939 B2 AU 652939B2
- Authority
- AU
- Australia
- Prior art keywords
- antagonist
- conjugate
- cytotoxin
- tumor
- binding agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
- A61K47/67—Enzyme prodrug therapy, e.g. gene directed enzyme drug therapy [GDEPT] or VDEPT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
- A61K47/6895—Rescue therapy; Agonist-antagonist; Antidotes; Targeted rescue or protection, e.g. by folic acid-folinic acid or conjugated to antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nanotechnology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52265390A | 1990-05-11 | 1990-05-11 | |
US522653 | 1990-05-11 | ||
PCT/US1991/003291 WO1991017761A1 (en) | 1990-05-11 | 1991-05-10 | Targeted protection from cytotoxins |
Publications (2)
Publication Number | Publication Date |
---|---|
AU7902691A AU7902691A (en) | 1991-12-10 |
AU652939B2 true AU652939B2 (en) | 1994-09-15 |
Family
ID=24081756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU79026/91A Ceased AU652939B2 (en) | 1990-05-11 | 1991-05-10 | Targeted protection from cytotoxins |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0538268A4 (ja) |
JP (1) | JPH05508398A (ja) |
AU (1) | AU652939B2 (ja) |
CA (1) | CA2082507A1 (ja) |
WO (1) | WO1991017761A1 (ja) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5490991A (en) * | 1986-07-03 | 1996-02-13 | Advanced Magnetics, Inc. | Directed delivery of radioprotectants using a receptor specific carrier |
DK0594803T3 (da) * | 1992-03-23 | 2004-03-08 | Kenneth Naoyuki Matsumura | Sammensætning til reduktion af bivirkninger af et lægemiddel |
US5449720A (en) * | 1993-05-24 | 1995-09-12 | Biotech Australia Pty Limited | Amplification of the VB12 uptake system using polymers |
WO1995018636A2 (en) * | 1994-01-11 | 1995-07-13 | Targetech Inc | Hepatocyte-targeted drug conjugates |
US5830686A (en) * | 1994-01-13 | 1998-11-03 | Calydon | Tissue-specific enhancer active in prostate |
US6057299A (en) * | 1994-01-13 | 2000-05-02 | Calydon, Inc. | Tissue-specific enhancer active in prostate |
ATE376062T1 (de) | 1997-08-04 | 2007-11-15 | Cell Genesys Inc | Enhancer des menschlichen glandulären kallikreingens, vektoren die ihn enthalten und methoden für seine verwendung |
GB0916749D0 (en) | 2009-09-23 | 2009-11-04 | Mologic Ltd | Peptide cleaning agents |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2579497B2 (ja) * | 1987-09-07 | 1997-02-05 | オリエンタル酵母工業株式会社 | 肝臓疾患診断剤 |
AU8628291A (en) * | 1990-09-25 | 1992-04-15 | University Of Connecticut, The | Prolonging expression of polynucleotides introduced into a cell |
-
1991
- 1991-05-10 WO PCT/US1991/003291 patent/WO1991017761A1/en not_active Application Discontinuation
- 1991-05-10 CA CA002082507A patent/CA2082507A1/en not_active Abandoned
- 1991-05-10 JP JP3509433A patent/JPH05508398A/ja active Pending
- 1991-05-10 EP EP19910910021 patent/EP0538268A4/en not_active Withdrawn
- 1991-05-10 AU AU79026/91A patent/AU652939B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU7902691A (en) | 1991-12-10 |
EP0538268A4 (en) | 1993-05-12 |
EP0538268A1 (en) | 1993-04-28 |
CA2082507A1 (en) | 1991-11-12 |
WO1991017761A1 (en) | 1991-11-28 |
JPH05508398A (ja) | 1993-11-25 |
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