AU651816B2 - Induction of protection against viral infection - Google Patents
Induction of protection against viral infection Download PDFInfo
- Publication number
- AU651816B2 AU651816B2 AU74989/91A AU7498991A AU651816B2 AU 651816 B2 AU651816 B2 AU 651816B2 AU 74989/91 A AU74989/91 A AU 74989/91A AU 7498991 A AU7498991 A AU 7498991A AU 651816 B2 AU651816 B2 AU 651816B2
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- Prior art keywords
- peptide
- hiv
- virus
- envelope glycoprotein
- host
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 101150012518 lamB gene Proteins 0.000 description 1
- 239000002523 lectin Substances 0.000 description 1
- 108010034897 lentil lectin Proteins 0.000 description 1
- 230000021633 leukocyte mediated immunity Effects 0.000 description 1
- 239000002960 lipid emulsion Substances 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 210000004779 membrane envelope Anatomy 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- 108700004028 nef Genes Proteins 0.000 description 1
- 239000013642 negative control Substances 0.000 description 1
- 238000007857 nested PCR Methods 0.000 description 1
- 229920002866 paraformaldehyde Polymers 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 210000005105 peripheral blood lymphocyte Anatomy 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 description 1
- 229920000656 polylysine Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 235000020004 porter Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000009696 proliferative response Effects 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 229960000814 tetanus toxoid Drugs 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- 229960004319 trichloroacetic acid Drugs 0.000 description 1
- 208000007089 vaccinia Diseases 0.000 description 1
- 108700026220 vif Genes Proteins 0.000 description 1
- 230000029812 viral genome replication Effects 0.000 description 1
- 210000000605 viral structure Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49474990A | 1990-03-19 | 1990-03-19 | |
| US494749 | 1990-03-19 | ||
| PCT/EP1991/000509 WO1991014449A1 (fr) | 1990-03-19 | 1991-03-16 | Induction de protection contre les infections virales |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU64615/94A Division AU6461594A (en) | 1990-03-19 | 1994-06-09 | Induction of protection against viral infection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU7498991A AU7498991A (en) | 1991-10-21 |
| AU651816B2 true AU651816B2 (en) | 1994-08-04 |
Family
ID=23965805
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU74989/91A Ceased AU651816B2 (en) | 1990-03-19 | 1991-03-16 | Induction of protection against viral infection |
| AU64615/94A Abandoned AU6461594A (en) | 1990-03-19 | 1994-06-09 | Induction of protection against viral infection |
| AU71960/98A Abandoned AU7196098A (en) | 1990-03-19 | 1998-06-16 | Induction of protection against viral infection |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU64615/94A Abandoned AU6461594A (en) | 1990-03-19 | 1994-06-09 | Induction of protection against viral infection |
| AU71960/98A Abandoned AU7196098A (en) | 1990-03-19 | 1998-06-16 | Induction of protection against viral infection |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP0742229A3 (fr) |
| JP (2) | JPH03271233A (fr) |
| AT (1) | ATE154244T1 (fr) |
| AU (3) | AU651816B2 (fr) |
| CA (1) | CA2057040A1 (fr) |
| DE (1) | DE69126486T2 (fr) |
| DK (1) | DK0472706T3 (fr) |
| ES (1) | ES2104695T3 (fr) |
| GR (1) | GR3024670T3 (fr) |
| WO (1) | WO1991014449A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5976541A (en) * | 1988-01-26 | 1999-11-02 | The United States Of America As Represented By The Department Of Health And Human Services | Potent peptide for stimulation of cytotoxic T lymphocytes specific for the HIV-1 envelope |
| US5876724A (en) * | 1990-03-19 | 1999-03-02 | Institut Pasteur | Induction of neutralizing antibody against viral infection by synergy between virus envelope glycoprotein and peptides corresponding to neutralization epitopes of the glycoprotein |
| US6139843A (en) * | 1991-04-02 | 2000-10-31 | Albert Einstein College Of Medicine Of Yeshiva University | Peptide compositions for the treatment of HIV |
| DE69233271T2 (de) * | 1991-04-02 | 2004-09-09 | Albert Einstein College Of Medicine Of Yeshiva University | Therapeutischer- und präventivimpfstoff gegen hiv |
| JPH07501052A (ja) * | 1991-10-28 | 1995-02-02 | インスティチュート・パスツール | ウイルスエンベロープタンパク質と糖タンパク質の中和エピトープに相当するペプチドとの間の相乗作用によるウイルス感染に対する防御の誘発 |
| FR2692898B1 (fr) * | 1992-06-30 | 1995-06-02 | Centre Nat Rech Scient | Procédé d'obtention de protéines membranaires, et utilisation de ces protéines dans un but de diagnostic ou de vaccination. |
| UA68327C2 (en) | 1995-07-04 | 2004-08-16 | Gsf Forschungszentrum Fur Unwe | A recombinant mva virus, an isolated eukaryotic cell, infected with recombinant mva virus, a method for production in vitro of polypeptides with use of said cell, a method for production in vitro of virus parts (variants), vaccine containing the recombinant mva virus, a method for immunization of animals |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0227169A2 (fr) * | 1985-12-17 | 1987-07-01 | Akzo N.V. | Réactif immunochimique |
| EP0317804A2 (fr) * | 1987-11-24 | 1989-05-31 | Abbott Laboratories | Peptides de VIH et méthodes de détection de VIH |
| EP0326109A2 (fr) * | 1988-01-29 | 1989-08-02 | New York Blood Center, Inc. | Immunogènes contenant des peptides avec une queue hydrophobique attachée pour adsorption à l'antigène de surface de l'hépatite B |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ221440A (en) * | 1986-08-20 | 1991-11-26 | Genetic Systems Corp | Composition containing monoclonal antibodies/peptides useful in treating and diagnosing hiv infections |
| CA1341285C (fr) * | 1988-02-12 | 2001-08-14 | Chang Yi Wang | Peptides synthetiques servant a la detection d'anticorps de la proteine de surface gp120 du virus hiv, destines au diagnostic du sida, ainsi que d'etats pre-sidatiques, ou aux fins de vaccins |
| FR2650954B1 (fr) * | 1989-08-18 | 1992-02-28 | Pasteur Institut | Composition resultant de la reunion d'un epitope b de la glycoproteine d'enveloppe d'un retrovirus du type iv et d'un epitope t issu d'une proteine distincte codee par ce retrovirus et leur application a la production d'anticorps protecteurs contre le sida |
-
1990
- 1990-11-30 JP JP2341189A patent/JPH03271233A/ja active Pending
-
1991
- 1991-03-16 EP EP96106172A patent/EP0742229A3/fr not_active Withdrawn
- 1991-03-16 ES ES91906386T patent/ES2104695T3/es not_active Expired - Lifetime
- 1991-03-16 WO PCT/EP1991/000509 patent/WO1991014449A1/fr active IP Right Grant
- 1991-03-16 AU AU74989/91A patent/AU651816B2/en not_active Ceased
- 1991-03-16 DK DK91906386.7T patent/DK0472706T3/da active
- 1991-03-16 CA CA002057040A patent/CA2057040A1/fr not_active Abandoned
- 1991-03-16 AT AT91906386T patent/ATE154244T1/de not_active IP Right Cessation
- 1991-03-16 DE DE69126486T patent/DE69126486T2/de not_active Expired - Fee Related
- 1991-03-16 EP EP91906386A patent/EP0472706B1/fr not_active Expired - Lifetime
- 1991-03-16 JP JP3506292A patent/JPH04506220A/ja active Pending
-
1994
- 1994-06-09 AU AU64615/94A patent/AU6461594A/en not_active Abandoned
-
1997
- 1997-09-10 GR GR970402313T patent/GR3024670T3/el unknown
-
1998
- 1998-06-16 AU AU71960/98A patent/AU7196098A/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0227169A2 (fr) * | 1985-12-17 | 1987-07-01 | Akzo N.V. | Réactif immunochimique |
| EP0317804A2 (fr) * | 1987-11-24 | 1989-05-31 | Abbott Laboratories | Peptides de VIH et méthodes de détection de VIH |
| EP0326109A2 (fr) * | 1988-01-29 | 1989-08-02 | New York Blood Center, Inc. | Immunogènes contenant des peptides avec une queue hydrophobique attachée pour adsorption à l'antigène de surface de l'hépatite B |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991014449A1 (fr) | 1991-10-03 |
| EP0742229A3 (fr) | 1998-06-03 |
| EP0472706A1 (fr) | 1992-03-04 |
| ATE154244T1 (de) | 1997-06-15 |
| EP0472706B1 (fr) | 1997-06-11 |
| EP0742229A2 (fr) | 1996-11-13 |
| JPH04506220A (ja) | 1992-10-29 |
| AU7196098A (en) | 1998-08-13 |
| GR3024670T3 (en) | 1997-12-31 |
| CA2057040A1 (fr) | 1991-09-20 |
| DE69126486T2 (de) | 1998-01-15 |
| ES2104695T3 (es) | 1997-10-16 |
| AU7498991A (en) | 1991-10-21 |
| DE69126486D1 (de) | 1997-07-17 |
| AU6461594A (en) | 1994-09-08 |
| DK0472706T3 (da) | 1997-12-29 |
| JPH03271233A (ja) | 1991-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |