AU638600B2 - Novel adenosine derivatives, their production and use - Google Patents

Novel adenosine derivatives, their production and use Download PDF

Info

Publication number
AU638600B2
AU638600B2 AU83032/91A AU8303291A AU638600B2 AU 638600 B2 AU638600 B2 AU 638600B2 AU 83032/91 A AU83032/91 A AU 83032/91A AU 8303291 A AU8303291 A AU 8303291A AU 638600 B2 AU638600 B2 AU 638600B2
Authority
AU
Australia
Prior art keywords
carbonate
ethylamide
desoxy
document
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU83032/91A
Other languages
English (en)
Other versions
AU8303291A (en
Inventor
Fulvio Gadient
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of AU8303291A publication Critical patent/AU8303291A/en
Application granted granted Critical
Publication of AU638600B2 publication Critical patent/AU638600B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU83032/91A 1990-08-16 1991-08-13 Novel adenosine derivatives, their production and use Ceased AU638600B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4025879A DE4025879A1 (de) 1990-08-16 1990-08-16 Neue adenosin derivate, deren herstellung und verwendung
DE4025879 1990-08-16

Publications (2)

Publication Number Publication Date
AU8303291A AU8303291A (en) 1992-03-17
AU638600B2 true AU638600B2 (en) 1993-07-01

Family

ID=6412310

Family Applications (1)

Application Number Title Priority Date Filing Date
AU83032/91A Ceased AU638600B2 (en) 1990-08-16 1991-08-13 Novel adenosine derivatives, their production and use

Country Status (11)

Country Link
EP (1) EP0496852A1 (fi)
JP (1) JPH05502889A (fi)
AU (1) AU638600B2 (fi)
CA (1) CA2064869A1 (fi)
CS (1) CS97892A3 (fi)
DE (1) DE4025879A1 (fi)
FI (1) FI921691A0 (fi)
HU (1) HUT60504A (fi)
PL (1) PL294368A1 (fi)
TW (1) TW197448B (fi)
WO (1) WO1992003463A1 (fi)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994007904A1 (en) * 1992-10-01 1994-04-14 Mcneilab, Inc. Derivatives of 7,8-disubstituted guanosines
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
CN114437159B (zh) * 2022-04-11 2022-06-28 佛山市晨康生物科技有限公司 一种环状碳酸酯核苷类化合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
US4514405A (en) * 1981-09-17 1985-04-30 Merck Patent Gesellschaft Mit Beschrankter Haftung Use of adenosine derivatives as anticonvulsants
DE3406533A1 (de) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
AU579412B2 (en) * 1984-10-26 1988-11-24 Warner-Lambert Company N` - substituted adenosines

Also Published As

Publication number Publication date
CA2064869A1 (en) 1992-02-17
CS97892A3 (en) 1992-08-12
TW197448B (fi) 1993-01-01
HUT60504A (en) 1992-09-28
AU8303291A (en) 1992-03-17
JPH05502889A (ja) 1993-05-20
EP0496852A1 (de) 1992-08-05
HU9201080D0 (en) 1992-06-29
DE4025879A1 (de) 1992-02-20
FI921691A0 (fi) 1992-04-15
PL294368A1 (en) 1993-06-28
WO1992003463A1 (de) 1992-03-05

Similar Documents

Publication Publication Date Title
TW420663B (en) Indole compounds for cyclic nucleotide-PDEs inhibitors
US6211158B1 (en) Desazapurine-nucleotide derivatives, processes for the preparation thereof, pharmaceutical compositions containing them and the use thereof for nucleic acid sequencing and as antiviral agents
EP0545966B1 (de) Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
NZ250414A (en) Substituted 5'-deoxy-5-fluorocytidines and pharmaceutical compositions
CZ342595A3 (en) Purine derivatives, process of their preparation and pharmaceutical compositions containing thereof
BG61669B2 (bg) Нови ксантинови производни с аденозин-антагонистично действие
SK10494A3 (en) 1,3-oxathiolane nucleoside analogues
EP0666269A2 (de) Nucleosid-Derivate und deren Verwendung als Arzneimittel
US5219840A (en) Antihypertensive 9-(2,N6 -disubstituted adenyl) ribofuranuronic acid derivatives
KR20110002465A (ko) 세포 보호 작용을 갖는 피리미딘 유도체 및 그 용도
FI81357C (fi) Foerfarande foer framstaellning av griseolinsyraderivat.
AU638600B2 (en) Novel adenosine derivatives, their production and use
EP0449175B1 (en) Selective adenosine receptor agents
US5534503A (en) 2'-O, N6 -disubstituted and 2'-O, N6, 2-trisubstituted adenosines and their medicinal uses
US4855288A (en) Furanuronic acid derivatives, process for their production and their use
IE914023A1 (en) New adenosine derivatives, their production and use
NZ240719A (en) Adenosine-2',3'-carbonates, process for their preparation and use thereof.
US4612317A (en) Tetrahydro-β-carboline dithioic acid derivatives and treatment of liver diseases
EP0649840B1 (en) Bis(hydroxymethyl)cyclopropylmethyl pyrimidine derivatives, their preparation and their use as anti-viral agents
CN112679489B (zh) N-磺酰基杂环衍生物及其制药用途
JPH0232094A (ja) 抗感染性ヌクレオシド
WO2003094912A1 (fr) Derives de bislactone et leur utilisation dans les compositions medicales
DE3906357A1 (de) Neue acyclische nucleosid-analoga, verfahren zu ihrer herstellung und verwendung dieser verbindungen als antivirale arzneimittel
US6107064A (en) Process for producing xanthine derivatives with bacteria and fungi
SEKI et al. Synthesis of 5-alkyl-4-oxazoleacetic acid derivatives with hypolipidemic activities