AU631693B2 - A83543 recovery process - Google Patents

A83543 recovery process

Info

Publication number
AU631693B2
AU631693B2 AU66414/90A AU6641490A AU631693B2 AU 631693 B2 AU631693 B2 AU 631693B2 AU 66414/90 A AU66414/90 A AU 66414/90A AU 6641490 A AU6641490 A AU 6641490A AU 631693 B2 AU631693 B2 AU 631693B2
Authority
AU
Australia
Prior art keywords
medium
phase
solvent
culture
methanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU66414/90A
Other languages
English (en)
Other versions
AU6641490A (en
Inventor
Patrick James Baker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU6641490A publication Critical patent/AU6641490A/en
Application granted granted Critical
Publication of AU631693B2 publication Critical patent/AU631693B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation, Recovery Or Treatment Of Waste Materials Containing Plastics (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Processing Of Solid Wastes (AREA)
AU66414/90A 1989-10-30 1990-10-26 A83543 recovery process Ceased AU631693B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US42944189A 1989-10-30 1989-10-30
US429441 1989-10-30
US45139489A 1989-12-15 1989-12-15
US451394 1989-12-15

Publications (2)

Publication Number Publication Date
AU6641490A AU6641490A (en) 1991-05-31
AU631693B2 true AU631693B2 (en) 1992-12-03

Family

ID=27028194

Family Applications (1)

Application Number Title Priority Date Filing Date
AU66414/90A Ceased AU631693B2 (en) 1989-10-30 1990-10-26 A83543 recovery process

Country Status (5)

Country Link
EP (1) EP0454820A4 (ja)
JP (1) JPH05504469A (ja)
AU (1) AU631693B2 (ja)
BR (1) BR9006982A (ja)
WO (1) WO1991006552A1 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
OA09249A (fr) * 1988-12-19 1992-06-30 Lilly Co Eli Composés de macrolides.
US5227295A (en) * 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
WO1994020518A1 (en) * 1993-03-12 1994-09-15 Dowelanco New a83543 compounds and process for production thereof
WO1995011295A1 (en) * 1993-10-22 1995-04-27 Gist-Brocades N.V. An improved process to recover an aqueous fermentation broth
US6001981A (en) * 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
GB2326020B (en) 1997-06-06 2002-05-15 Ericsson Telefon Ab L M Waveguide
DE102005018256B3 (de) * 2005-04-20 2006-08-31 Dechema Gesellschaft Für Chemische Technik Und Biotechnologie E.V. Verfahren zur fermentativen Herstellung von Duft- und/oder Aromastoffen

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4213966A (en) * 1977-06-02 1980-07-22 E. R. Squibb & Sons, Inc. Method for isolating polyether antibiotics
US4366308A (en) * 1979-08-13 1982-12-28 Sapporo Breweries Limited Process for the production of polysaccharide RBS substance
US4764602A (en) * 1985-06-20 1988-08-16 Sumitomo Chemical Company Antibiotics, and their production

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2881162A (en) * 1953-11-16 1959-04-07 Abbott Lab Recovery process
US4321329A (en) * 1979-10-02 1982-03-23 The Upjohn Company Saccharopolyspora culture
US4251511A (en) * 1979-10-02 1981-02-17 The Upjohn Company Antibiotic and fermentation process of preparing
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4213966A (en) * 1977-06-02 1980-07-22 E. R. Squibb & Sons, Inc. Method for isolating polyether antibiotics
US4366308A (en) * 1979-08-13 1982-12-28 Sapporo Breweries Limited Process for the production of polysaccharide RBS substance
US4764602A (en) * 1985-06-20 1988-08-16 Sumitomo Chemical Company Antibiotics, and their production

Also Published As

Publication number Publication date
WO1991006552A1 (en) 1991-05-16
JPH05504469A (ja) 1993-07-15
BR9006982A (pt) 1991-12-24
AU6641490A (en) 1991-05-31
EP0454820A1 (en) 1991-11-06
EP0454820A4 (en) 1992-03-11

Similar Documents

Publication Publication Date Title
EP0573628B1 (en) New a83543 compounds and process for production thereof
US5227295A (en) Process for isolating A83543 and its components
AU624458B2 (en) Macrolide compounds
US4160861A (en) Method for the separation of antibiotic macrolides
EP0388152B1 (en) Process for producing an immunosuppressant agent (demethimmunomycin) using a mutant strain of a microorganism
AU631693B2 (en) A83543 recovery process
US5563054A (en) Process for preparation of benzo[B]thiophene glucuronides
US4252898A (en) Antibiotics A6888C and A6888X
US4161583A (en) Method for the separation and purification of antibiotic macrolides
CA1092999A (en) Method for producing maytansinol and its derivatives
EP0043280B1 (en) Process for preparing a macrolide
US4172940A (en) Purification of C-076 compounds by single column chromatography
US4440857A (en) Process for preparing mycarosyltylactone
CA1211731A (en) De(mycinosyloxy)tylosin derivatives
JPH0737B2 (ja) スタウロスポリン発酵法
US4160083A (en) Process for the separation of antibiotic macrolides
EP0466365A2 (en) Novel immunosuppressant fermentation products of a microorganism
US4358584A (en) Antibiotics A6888C and A6888X
EP0526906A1 (en) Process for producing 3-deacylated derivatives of a 16-membered macrolide antibiotic, microorganism to be used therefor and novel macrolide antibiotic
CA1113874A (en) Antibiotic bl580 zeta from streptomyces hydroscopicus
US4296101A (en) Antibiotic kristenin
EP0045205B1 (en) Macrolides
JPH0639480B2 (ja) 新規マクロライド系抗生物質ｍ１１９
EP0037736A1 (en) Mycoplanecin derivatives, their preparation and pharmaceutical compositions containing them
US2965547A (en) Process for the production of l-6-diazo-5-oxonorleucine