AU631235B2 - New oral pharmaceutical dosage form improving bioavailability - Google Patents

New oral pharmaceutical dosage form improving bioavailability

Info

Publication number
AU631235B2
AU631235B2 AU60239/90A AU6023990A AU631235B2 AU 631235 B2 AU631235 B2 AU 631235B2 AU 60239/90 A AU60239/90 A AU 60239/90A AU 6023990 A AU6023990 A AU 6023990A AU 631235 B2 AU631235 B2 AU 631235B2
Authority
AU
Australia
Prior art keywords
dosage form
pharmaceutical dosage
oral pharmaceutical
new oral
improving bioavailability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU60239/90A
Other versions
AU6023990A (en
Inventor
Jean-Marc Alache
Denis Besancon
Alain Dufor
Fabrice Egros
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Delagrange SA
Original Assignee
Laboratoires Delagrange SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Delagrange SA filed Critical Laboratoires Delagrange SA
Publication of AU6023990A publication Critical patent/AU6023990A/en
Application granted granted Critical
Publication of AU631235B2 publication Critical patent/AU631235B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU60239/90A 1989-08-07 1990-08-06 New oral pharmaceutical dosage form improving bioavailability Ceased AU631235B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8910605 1989-08-07
FR8910605A FR2650502B1 (en) 1989-08-07 1989-08-07 NEW ORAL GALENIC FORM IMPROVING BIOAVAILABILITY

Publications (2)

Publication Number Publication Date
AU6023990A AU6023990A (en) 1991-02-07
AU631235B2 true AU631235B2 (en) 1992-11-19

Family

ID=9384532

Family Applications (1)

Application Number Title Priority Date Filing Date
AU60239/90A Ceased AU631235B2 (en) 1989-08-07 1990-08-06 New oral pharmaceutical dosage form improving bioavailability

Country Status (25)

Country Link
EP (1) EP0412877A1 (en)
JP (1) JPH0377819A (en)
KR (1) KR910004181A (en)
CN (1) CN1049455A (en)
AU (1) AU631235B2 (en)
CA (1) CA2022447A1 (en)
CS (1) CS276556B6 (en)
DD (1) DD297332A5 (en)
DE (1) DE4023136A1 (en)
FI (1) FI903885A0 (en)
FR (1) FR2650502B1 (en)
GB (1) GB2234898A (en)
HU (1) HU204997B (en)
IE (1) IE902629A1 (en)
IL (1) IL95105A0 (en)
IN (1) IN170789B (en)
LU (1) LU87777A1 (en)
MA (1) MA21923A1 (en)
NO (1) NO903442L (en)
NZ (1) NZ234593A (en)
OA (1) OA09301A (en)
PE (1) PE491A1 (en)
PT (1) PT94823A (en)
TN (1) TNSN90111A1 (en)
ZA (1) ZA905886B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU679906B2 (en) * 1992-01-17 1997-07-17 Alfatec-Pharma Gmbh Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
DE4221880A1 (en) * 1992-07-03 1994-01-05 Alfatec Pharma Gmbh Solid and liquid solutions of poorly water-soluble drugs
KR20030089147A (en) * 2002-05-16 2003-11-21 슈라펫 주식회사 Water bottle for pet

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2159407A (en) * 1982-12-02 1985-12-04 Takada Seiyaku Kabushiki Kaish Solid water-soluble nifedipine preparation

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE854414C (en) * 1949-04-26 1952-11-04 Dieter Dr Med Ellenbeck Process for the production of injectable solutions of more or less poorly soluble medicaments
GB715874A (en) * 1952-10-03 1954-09-22 Horlicks Ltd A tablet for use in treating peptic ulcers
GB906422A (en) * 1958-05-02 1962-09-19 Wellcome Found Improvements in and relating to prolonged acting pharmaceutical preparations
US3015611A (en) * 1959-08-25 1962-01-02 Nysco Lab Inc Low density whey-bound tablets
GB1063872A (en) * 1962-08-11 1967-03-30 Wellcome Found Improvements in and relating to prolonged acting pharmaceutical compositions
US3594467A (en) * 1968-10-09 1971-07-20 Richardson Merrell Inc Long-lasting troche
US3922379A (en) * 1973-12-17 1975-11-25 Abbott Lab Microencapsulation process
US4107288A (en) * 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
DE3250023T (en) * 1981-01-14 1990-03-29
FR2524312B1 (en) * 1982-04-01 1985-10-04 Tech Cuir Centre NOVEL FORMS OF MICRO-ENCAPSULATION OF DRUG SUBSTANCES BY HOMOGENEOUS LAYERS OF NATIVE COLLAGEN
CA1249968A (en) * 1984-04-05 1989-02-14 Kazuo Kigasawa Ointment base
US4670251A (en) * 1984-05-30 1987-06-02 Igene Biotechnology, Inc. Microcrystalline tableting excipient derived from whey
NZ217844A (en) * 1985-10-11 1989-10-27 Sumitomo Pharma A sustained release pharmaceutical composition containing silicone elastomer and an albumin
IL78017A (en) * 1986-03-03 1989-06-30 Yissum Res Dev Co Sustained release tablets of theophylline
DE3702105A1 (en) * 1987-01-24 1988-08-04 Bayer Ag PARENTERAL SOLUTION
WO1988006457A1 (en) * 1987-03-04 1988-09-07 Nippon Hypox Laboratories Incorporated Medicinal composition containing albumin as carrier and process for its preparation
CA1324083C (en) * 1987-03-09 1993-11-09 Tetsu Miyoshi Pharmaceutical preparations containing non-steroidal anti-inflammatory agents
DK179687D0 (en) * 1987-04-08 1987-04-08 Farma Food As PREPARATION
ES2054815T3 (en) * 1987-09-08 1994-08-16 Takeda Chemical Industries Ltd INSOLUBILIZED CYTOKINES IN WATER.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2159407A (en) * 1982-12-02 1985-12-04 Takada Seiyaku Kabushiki Kaish Solid water-soluble nifedipine preparation

Also Published As

Publication number Publication date
DE4023136A1 (en) 1991-02-14
PT94823A (en) 1991-04-18
KR910004181A (en) 1991-03-28
IN170789B (en) 1992-05-23
MA21923A1 (en) 1991-04-01
TNSN90111A1 (en) 1991-03-05
NO903442D0 (en) 1990-08-06
CS383890A3 (en) 1992-06-17
GB2234898A (en) 1991-02-20
CA2022447A1 (en) 1991-02-08
JPH0377819A (en) 1991-04-03
OA09301A (en) 1992-09-15
CN1049455A (en) 1991-02-27
GB9017144D0 (en) 1990-09-19
FR2650502B1 (en) 1994-05-27
AU6023990A (en) 1991-02-07
CS276556B6 (en) 1992-06-17
ZA905886B (en) 1991-04-24
FI903885A0 (en) 1990-08-06
HU904909D0 (en) 1991-01-28
HUT55230A (en) 1991-05-28
HU204997B (en) 1992-03-30
IL95105A0 (en) 1991-06-10
NZ234593A (en) 1993-04-28
DD297332A5 (en) 1992-01-09
PE491A1 (en) 1991-01-26
EP0412877A1 (en) 1991-02-13
IE902629A1 (en) 1991-02-27
LU87777A1 (en) 1990-12-11
FR2650502A1 (en) 1991-02-08
NO903442L (en) 1991-02-08

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