AU614515B2 - A pharmaceutical combination for the prophylaxis and therapy of malaria - Google Patents

A pharmaceutical combination for the prophylaxis and therapy of malaria Download PDF

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Publication number
AU614515B2
AU614515B2 AU15675/88A AU1567588A AU614515B2 AU 614515 B2 AU614515 B2 AU 614515B2 AU 15675/88 A AU15675/88 A AU 15675/88A AU 1567588 A AU1567588 A AU 1567588A AU 614515 B2 AU614515 B2 AU 614515B2
Authority
AU
Australia
Prior art keywords
group
arteether
pharmaceutical combination
dihydroartemisinine
chloroquine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU15675/88A
Other languages
English (en)
Other versions
AU1567588A (en
Inventor
Dipak Kumar Chatterjee
Bansi Lal
Richard Helmut Rupp
Noel John De Souza
Bindumadhavan Venugopalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU1567588A publication Critical patent/AU1567588A/en
Application granted granted Critical
Publication of AU614515B2 publication Critical patent/AU614515B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/49—Cinchonan derivatives, e.g. quinine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU15675/88A 1987-05-08 1988-05-06 A pharmaceutical combination for the prophylaxis and therapy of malaria Ceased AU614515B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873715378 DE3715378A1 (de) 1987-05-08 1987-05-08 Arzneimittelkombination zur prophylaxe und therapie von malaria
DE3715378 1987-05-08

Publications (2)

Publication Number Publication Date
AU1567588A AU1567588A (en) 1988-11-10
AU614515B2 true AU614515B2 (en) 1991-09-05

Family

ID=6327117

Family Applications (1)

Application Number Title Priority Date Filing Date
AU15675/88A Ceased AU614515B2 (en) 1987-05-08 1988-05-06 A pharmaceutical combination for the prophylaxis and therapy of malaria

Country Status (11)

Country Link
EP (1) EP0290959A3 (OSRAM)
JP (1) JPS6452714A (OSRAM)
KR (1) KR880013558A (OSRAM)
AU (1) AU614515B2 (OSRAM)
DE (1) DE3715378A1 (OSRAM)
DK (1) DK249688A (OSRAM)
HU (1) HU200688B (OSRAM)
IL (1) IL86302A0 (OSRAM)
IN (1) IN166154B (OSRAM)
PT (1) PT87427B (OSRAM)
ZA (1) ZA883209B (OSRAM)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916204A (en) * 1987-07-31 1990-04-10 Massachusetts Institute Of Technology Pure polyanhydride from dicarboxylic acid and coupling agent
AU625071B2 (en) * 1988-04-20 1992-07-02 Merrell Dow Pharmaceuticals Inc. N-alkylamino derivatives of aromatic, tricyclic compounds in the treatment of drug-resistant protozoal infections
DE68906345T2 (de) * 1988-10-07 1993-10-28 Hoechst Ag Antimalariazusammenstellungen, gebrauchmachend von Quinidin, Artemisinin und ihren Derivaten.
EP0535719A3 (en) * 1988-12-06 1993-04-14 Dermatologic Research Corporation Treatment of hemorrhoids with artemisinin and derivates
EP0464233A1 (en) * 1990-07-02 1992-01-08 Hoechst Aktiengesellschaft Pharmaceutical combinations against malaria
AU668376B2 (en) * 1992-02-07 1996-05-02 Novartis Ag Antimalarial synergistic compositions containing benflumetol
GB9622427D0 (en) * 1996-10-28 1997-01-08 Pharma Mar Sa Antimalarial drugs
US6160004A (en) * 1997-12-30 2000-12-12 Hauser, Inc. C-10 carbon-substituted artemisinin-like trioxane compounds having antimalarial, antiproliferative and antitumor activities
IN191696B (OSRAM) * 1999-02-12 2003-12-20 Council Scient Ind Res
AU2000255627A1 (en) * 2000-03-28 2001-10-08 Council Of Scientific And Industrial Research A novel anti-microbial composition and method for producing the same
WO2002032905A1 (en) * 2000-10-20 2002-04-25 Ajinomoto Co.,Inc. Medicinal compositions, dose and method for treating malaria
CN1255106C (zh) * 2003-09-26 2006-05-10 李国桥 复方青蒿素
WO2006070393A1 (en) * 2004-12-28 2006-07-06 Council Of Scientific And Industrial Research SYNERGISTIC COMBINATION KIT OF α,ß-ARTEETHER, SULFADOXIN AND PYMETHAMINE FOR TREATMENT OF SEVERE/MULTI-DRUG RESISTANT CEREBRAL MALARIA
FR2884715B1 (fr) * 2005-04-20 2007-06-15 Sanofi Aventis Sa Association entre la ferroquine et un derive d'artemisinine pour le traitement du paludisme
WO2007043061A1 (en) * 2005-10-11 2007-04-19 Ipca Laboratories Ltd. Anti-malarial combination and methods of formulation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3302389A (en) * 1988-04-20 1989-10-26 Merrell Dow Pharmaceuticals Inc. N-alkylamino derivatives of aromatic, tricyclic compounds in the treatment of drug-resistant protozoal infections
AU4263789A (en) * 1988-10-07 1990-04-12 Hoechst Aktiengesellschaft Antimalarial compositions and methods of treatment using quinidine, artemisinine and its derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3302389A (en) * 1988-04-20 1989-10-26 Merrell Dow Pharmaceuticals Inc. N-alkylamino derivatives of aromatic, tricyclic compounds in the treatment of drug-resistant protozoal infections
AU4263789A (en) * 1988-10-07 1990-04-12 Hoechst Aktiengesellschaft Antimalarial compositions and methods of treatment using quinidine, artemisinine and its derivatives

Also Published As

Publication number Publication date
EP0290959A3 (de) 1990-03-07
PT87427B (pt) 1992-09-30
HU200688B (en) 1990-08-28
KR880013558A (ko) 1988-12-21
HUT47846A (en) 1989-04-28
PT87427A (pt) 1989-05-31
IL86302A0 (en) 1988-11-15
DE3715378A1 (de) 1988-11-24
DK249688D0 (da) 1988-05-06
AU1567588A (en) 1988-11-10
JPS6452714A (en) 1989-02-28
ZA883209B (en) 1988-11-08
IN166154B (OSRAM) 1990-03-24
DK249688A (da) 1988-11-09
EP0290959A2 (de) 1988-11-17

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