AU6049800A - Method of changing conformation of a matrix metalloproteinase - Google Patents

Method of changing conformation of a matrix metalloproteinase

Info

Publication number
AU6049800A
AU6049800A AU60498/00A AU6049800A AU6049800A AU 6049800 A AU6049800 A AU 6049800A AU 60498/00 A AU60498/00 A AU 60498/00A AU 6049800 A AU6049800 A AU 6049800A AU 6049800 A AU6049800 A AU 6049800A
Authority
AU
Australia
Prior art keywords
matrix metalloproteinase
changing conformation
conformation
changing
metalloproteinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU60498/00A
Other languages
English (en)
Inventor
Gary A. De Crecenzo
Susan C. Howard
Joseph J. Mcdonald
Huey S. Shieh
William C. Stallings
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of AU6049800A publication Critical patent/AU6049800A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46—Y being a hydrogen or a carbon atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU60498/00A 1999-07-16 2000-07-12 Method of changing conformation of a matrix metalloproteinase Abandoned AU6049800A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14413399P 1999-07-16 1999-07-16
US60144133 1999-07-16
PCT/US2000/016323 WO2001005389A2 (fr) 1999-07-16 2000-07-12 Methode de changement de la conformation d'une metalloproteinase matricielle

Publications (1)

Publication Number Publication Date
AU6049800A true AU6049800A (en) 2001-02-05

Family

ID=22507217

Family Applications (1)

Application Number Title Priority Date Filing Date
AU60498/00A Abandoned AU6049800A (en) 1999-07-16 2000-07-12 Method of changing conformation of a matrix metalloproteinase

Country Status (2)

Country Link
AU (1) AU6049800A (fr)
WO (1) WO2001005389A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DOP2002000333A (es) 2001-02-14 2002-09-30 Warner Lambert Co Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz
US7504431B2 (en) 2004-04-16 2009-03-17 Bristol-Myers Squibb Company Sulfonyl amide inhibitors of calcium channel function

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR980009238A (ko) * 1995-07-28 1998-04-30 우에노 도시오 설포닐아미노산 유도체
US6022893A (en) * 1995-08-08 2000-02-08 Ono Pharmaceutical Co., Ltd. Hydroxamic acid derivatives
DE69737605T2 (de) * 1996-01-23 2008-04-03 Shionogi & Co., Ltd. Sulfonierte aminosäurederivate und metalloproteinase-inhibitoren, die diese enthalten
JP2000515153A (ja) * 1996-07-22 2000-11-14 モンサント カンパニー チオールスルホンアミド メタロプロテアーゼインヒビター
DE69827940T2 (de) * 1997-03-04 2005-06-09 Pharmacia Corp.(N.D.Ges.D.Staates Delaware) Thiarylsulfonamid-hydroxamsäurederivate
KR100279519B1 (ko) * 1998-02-18 2001-02-01 이본수 비산계니트로화공정에의한방향족화합물의니트로화방법
JPH11236369A (ja) * 1998-02-23 1999-08-31 Kotobuki Seiyaku Kk スルホンアミド誘導体及びその製造法並びにこれを含有する医薬組成物
JPH11246527A (ja) * 1998-03-02 1999-09-14 Shionogi & Co Ltd Ｍｍｐ−８阻害剤

Also Published As

Publication number Publication date
WO2001005389A2 (fr) 2001-01-25
WO2001005389A3 (fr) 2001-08-02

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase