AU604739B2 - 5-hetero- or aryl- substituted-imidazo(2,1-a) isoquinolines - Google Patents

5-hetero- or aryl- substituted-imidazo(2,1-a) isoquinolines Download PDF

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Publication number
AU604739B2
AU604739B2 AU76941/87A AU7694187A AU604739B2 AU 604739 B2 AU604739 B2 AU 604739B2 AU 76941/87 A AU76941/87 A AU 76941/87A AU 7694187 A AU7694187 A AU 7694187A AU 604739 B2 AU604739 B2 AU 604739B2
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AU
Australia
Prior art keywords
international
compound
formula
document
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU76941/87A
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English (en)
Other versions
AU7694187A (en
Inventor
William Joseph Houlihan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of AU7694187A publication Critical patent/AU7694187A/en
Application granted granted Critical
Publication of AU604739B2 publication Critical patent/AU604739B2/en
Assigned to NOVARTIS AG reassignment NOVARTIS AG Request to Amend Deed and Register Assignors: SANDOZ AG
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
AU76941/87A 1986-07-14 1987-07-07 5-hetero- or aryl- substituted-imidazo(2,1-a) isoquinolines Ceased AU604739B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88511586A 1986-07-14 1986-07-14
US885115 1986-07-14
US1351587A 1987-02-11 1987-02-11
US013515 1993-02-04

Publications (2)

Publication Number Publication Date
AU7694187A AU7694187A (en) 1988-02-10
AU604739B2 true AU604739B2 (en) 1991-01-03

Family

ID=26684931

Family Applications (1)

Application Number Title Priority Date Filing Date
AU76941/87A Ceased AU604739B2 (en) 1986-07-14 1987-07-07 5-hetero- or aryl- substituted-imidazo(2,1-a) isoquinolines

Country Status (22)

Country Link
EP (1) EP0258175B1 (Direct)
JP (1) JPH01500270A (Direct)
KR (1) KR960003609B1 (Direct)
AT (1) ATE74357T1 (Direct)
AU (1) AU604739B2 (Direct)
CA (1) CA1317942C (Direct)
CY (1) CY1828A (Direct)
DE (1) DE3777919D1 (Direct)
DK (1) DK170213B1 (Direct)
ES (1) ES2032861T3 (Direct)
FI (1) FI88159C (Direct)
GR (1) GR3004258T3 (Direct)
HK (1) HK71295A (Direct)
HU (1) HU206114B (Direct)
IE (1) IE60277B1 (Direct)
IL (1) IL83164A (Direct)
MY (1) MY101895A (Direct)
NZ (1) NZ221054A (Direct)
PH (1) PH24430A (Direct)
PL (1) PL154159B1 (Direct)
SG (1) SG8595G (Direct)
WO (1) WO1988000587A2 (Direct)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU632487B2 (en) * 1988-07-29 1993-01-07 Novartis Ag Improvements in or relating to organic compounds

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0338993A1 (en) * 1988-04-21 1989-10-25 Sandoz Ag 6-Aryl-substituted-4h-thieno[2,3-e][1,2,4]triazolo [3,4-c][1,4]diazepines
ES2069606T3 (es) * 1988-05-05 1995-05-16 Sandoz Ag 5-aril-sustituido-2,3-dihidro-imidazo(1,2-a)furo(3,2-c)- o tieno(2,3-c)piridinas.
US5939090A (en) 1996-12-03 1999-08-17 3M Innovative Properties Company Gel formulations for topical drug delivery
CN1076728C (zh) * 1999-02-05 2001-12-26 浙江大学 2－芳基咪唑并[2,1－a]异喹啉的衍生物及其用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887566A (en) * 1971-02-11 1975-06-03 Aspro Nicholas Ltd 2,3-Dihydroimidazo-isoquinolines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887566A (en) * 1971-02-11 1975-06-03 Aspro Nicholas Ltd 2,3-Dihydroimidazo-isoquinolines

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU632487B2 (en) * 1988-07-29 1993-01-07 Novartis Ag Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
PH24430A (en) 1990-06-25
ATE74357T1 (de) 1992-04-15
DK138388D0 (da) 1988-03-14
ES2032861T3 (es) 1993-03-01
IE60277B1 (en) 1994-06-29
FI881165A0 (fi) 1988-03-11
FI88159B (fi) 1992-12-31
DK170213B1 (da) 1995-06-19
PL266801A1 (en) 1988-09-29
AU7694187A (en) 1988-02-10
KR960003609B1 (en) 1996-03-20
PL154159B1 (en) 1991-07-31
WO1988000587A3 (en) 1988-04-07
CA1317942C (en) 1993-05-18
JPH0588713B2 (Direct) 1993-12-24
IL83164A (en) 1991-05-12
HU206114B (en) 1992-08-28
WO1988000587A2 (en) 1988-01-28
EP0258175A2 (en) 1988-03-02
NZ221054A (en) 1990-10-26
IL83164A0 (en) 1987-12-31
DE3777919D1 (de) 1992-05-07
MY101895A (en) 1992-02-15
FI881165A7 (fi) 1988-03-11
JPH01500270A (ja) 1989-02-02
DK138388A (da) 1988-03-14
KR880701718A (ko) 1988-11-04
HK71295A (en) 1995-05-19
FI88159C (fi) 1993-04-13
HUT46005A (en) 1988-09-28
EP0258175B1 (en) 1992-04-01
SG8595G (en) 1995-06-16
CY1828A (en) 1995-12-01
GR3004258T3 (Direct) 1993-03-31
EP0258175A3 (en) 1988-05-04
IE871876L (en) 1988-01-14

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired