AU582380B2 - Derivatised nucleic acid sequences - Google Patents

Derivatised nucleic acid sequences

Info

Publication number
AU582380B2
AU582380B2 AU46484/85A AU4648485A AU582380B2 AU 582380 B2 AU582380 B2 AU 582380B2 AU 46484/85 A AU46484/85 A AU 46484/85A AU 4648485 A AU4648485 A AU 4648485A AU 582380 B2 AU582380 B2 AU 582380B2
Authority
AU
Australia
Prior art keywords
nucleic acid
cytosine
acid sequences
nuclein
derivatised
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU46484/85A
Other languages
English (en)
Other versions
AU4648485A (en
Inventor
Hermann Graf
Helmut Lenz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of AU4648485A publication Critical patent/AU4648485A/en
Application granted granted Critical
Publication of AU582380B2 publication Critical patent/AU582380B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AU46484/85A 1984-08-28 1985-08-21 Derivatised nucleic acid sequences Expired AU582380B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3431536 1984-08-28
DE19843431536 DE3431536A1 (de) 1984-08-28 1984-08-28 Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren

Publications (2)

Publication Number Publication Date
AU4648485A AU4648485A (en) 1986-03-06
AU582380B2 true AU582380B2 (en) 1989-03-23

Family

ID=6244044

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46484/85A Expired AU582380B2 (en) 1984-08-28 1985-08-21 Derivatised nucleic acid sequences

Country Status (6)

Country Link
EP (1) EP0173251B1 (cg-RX-API-DMAC7.html)
JP (1) JPS6160697A (cg-RX-API-DMAC7.html)
AT (1) ATE48141T1 (cg-RX-API-DMAC7.html)
AU (1) AU582380B2 (cg-RX-API-DMAC7.html)
CA (1) CA1242657A (cg-RX-API-DMAC7.html)
DE (2) DE3431536A1 (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621572B2 (en) * 1987-10-28 1992-03-19 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02503983A (ja) * 1987-06-26 1990-11-22 イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー 捕捉ビーズを用いる組み換えクローン化ｎａからの混入配列のアフイニテイ除去
EP0972779A3 (en) * 1987-10-28 2004-10-20 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates
US5525465A (en) * 1987-10-28 1996-06-11 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates and methods of production and applications of the same
DE3813278A1 (de) * 1988-01-12 1989-07-20 Boehringer Mannheim Gmbh Verfahren zum nachweis von nukleinsaeuren
US5354657A (en) * 1988-01-12 1994-10-11 Boehringer Mannheim Gmbh Process for the highly specific detection of nucleic acids in solid
DE3800644A1 (de) * 1988-01-12 1989-07-20 Boehringer Mannheim Gmbh Verfahren zum hochspezifischen nachweis von nukleinsaeuren in loesung
FR2627590A1 (fr) * 1988-02-24 1989-08-25 Ire Celltarg Sa Sonde d'acides nucleiques comportant un nucleotide terminal modifie chimiquement en 5(prime) (oh) en vue de son marquage non radioactif et procedes de preparation
FR2634211B1 (fr) * 1988-07-13 1992-06-26 Lebacq Philippe Procede de marquage d'une sonde nucleique et trousse de reactifs pour la mise en oeuvre de ce procede
FR2644163B2 (fr) * 1988-07-13 1994-09-30 Bioprobe Systems Sa Procede de marquage d'une sonde nucleique et trousse de reactifs pour la mise en oeuvre de ce procede
DE3836656A1 (de) * 1988-10-27 1990-05-03 Boehringer Mannheim Gmbh Neue digoxigenin-derivate und ihre verwendung
US5356773A (en) * 1989-05-16 1994-10-18 Kinetic Investments Limited Generation of unidirectional deletion mutants
DE3916595A1 (de) * 1989-05-22 1990-11-29 Boehringer Mannheim Gmbh Verfahren zur nichtradioaktiven messung der nucleinsaeuresynthese in eukaryontischen zellen
DE3916871A1 (de) * 1989-05-24 1990-11-29 Boehringer Mannheim Gmbh Modifiziertes phosphoramidit-verfahren zur herstellung von modifizierten nukleinsaeuren
EP0422861B1 (en) * 1989-10-13 2000-05-17 Zeneca Limited Probes
US5677440A (en) * 1990-07-16 1997-10-14 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates
EP0752474A1 (en) 1995-07-07 1997-01-08 Boehringer Mannheim Gmbh Nucleic acid coding for CMP-N-acetyl-neuraminic acid hydroxylase and its use for the production of modified glycoproteins
JPH11509100A (ja) * 1995-07-13 1999-08-17 イムノロジカル アソシエーツ オブ デンバー 核酸抽出、増幅および検出を統合する自己充足装置
EP1006184A1 (en) 1998-12-03 2000-06-07 F. Hoffmann-La Roche Ag IGF-1 receptor interacting proteins (IIPs) genes coding therefor and uses thereof
US20020146728A1 (en) 1998-12-03 2002-10-10 Tanja Ligensa IGF-1 receptor interacting proteins
EP1099757B1 (en) 1999-11-11 2010-02-24 F. Hoffmann-La Roche Ag Process for the determination of CTp11 and for determining whether a tumor sample has metatastic potential
US7108977B2 (en) 2000-05-19 2006-09-19 Hoffmann-La Roche Inc. Process for determining the tumoricidal potential of a sample the use of a nucleic acid which is downregulated in human tumor cells
WO2006054507A1 (ja) 2004-11-19 2006-05-26 Matsushita Electric Industrial Co., Ltd. 動画像符号化方法及び動画像復号方法
WO2006098464A1 (ja) 2005-03-14 2006-09-21 Link Genomics, Inc. 前立腺がんの診断方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1820883A (en) * 1982-06-17 1984-01-16 Imreg Inc. Sensitive tests for malignancies based on dna detection
AU2379884A (en) * 1983-01-27 1984-08-02 Enzo Biochem Inc. Methods and structures employing non-radioactive chemically labelled polynucleotide probes
AU3048384A (en) * 1983-07-14 1985-01-17 Molecular Diagnostics, Inc. Labelled nucleic acid probes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
CA1219824A (en) * 1981-04-17 1987-03-31 David C. Ward Modified nucleotides and methods of preparing and using same
FR2519005B1 (fr) * 1981-12-29 1985-10-25 Pasteur Institut Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
EP0135587B2 (en) * 1983-02-22 2002-12-18 Syngene, Inc. Defined sequence single strand oligonucleotides incorporating reporter groups, process for the chemical synthesis thereof, and nucleosides useful in such synthesis
US4626501A (en) * 1983-09-02 1986-12-02 Integrated Genetics, Inc. Labeled DNA
FR2558172B1 (fr) * 1984-01-16 1986-06-13 Inst Nat Sante Rech Med Sonde contenant un acide nucleique modifie et reconnaissance par des anticorps specifiques et utilisation de cette sonde et de ces anticorps specifiques pour detecter et caracteriser une sequence d'adn homologue

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1820883A (en) * 1982-06-17 1984-01-16 Imreg Inc. Sensitive tests for malignancies based on dna detection
AU2379884A (en) * 1983-01-27 1984-08-02 Enzo Biochem Inc. Methods and structures employing non-radioactive chemically labelled polynucleotide probes
AU3048384A (en) * 1983-07-14 1985-01-17 Molecular Diagnostics, Inc. Labelled nucleic acid probes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621572B2 (en) * 1987-10-28 1992-03-19 Howard Florey Institute Of Experimental Physiology And Medicine Oligonucleotide-polyamide conjugates

Also Published As

Publication number Publication date
ATE48141T1 (de) 1989-12-15
EP0173251A3 (en) 1986-10-29
CA1242657A (en) 1988-10-04
JPH0578320B2 (cg-RX-API-DMAC7.html) 1993-10-28
EP0173251B1 (de) 1989-11-23
DE3574383D1 (en) 1989-12-28
DE3431536A1 (de) 1986-03-13
AU4648485A (en) 1986-03-06
JPS6160697A (ja) 1986-03-28
EP0173251A2 (de) 1986-03-05

Similar Documents

Publication Publication Date Title
AU582380B2 (en) Derivatised nucleic acid sequences
DK194688D0 (da) Desaza-purin-nucleosid-derivater, fremgangsmaade til fremstilling deraf samt anvendelse deraf
ATE295849T1 (de) Aryl-ester phosphoramidatderivate von 2',3'- didehydronukleoside
DK0679657T3 (da) Nukleosider og oligonukleotider med 2'-ethergrupper
DE69827013D1 (de) Basenanaloga
ATE224396T1 (de) N-substituierte-dihydroxyborylalkyl derivate von purin, indol und pyrimidin, geeignet als inhibitore von entzündliche cytokine
MA21030A1 (fr) Derives de la benzhydryloxyethyl-piperazine et procede d'obtention les contenant .
ATE124412T1 (de) Antivirusderivate von (phosphonmethoxy)methoxy purin/pyrimidin.
RU96122489A (ru) Способ получения 4,6-дихлорпиримидина
KR870006033A (ko) 피리디닐 피리미딘 유도체의 제조 방법
ATE78269T1 (de) Elektrotauchlack.
CS19884A2 (en) Zpusob vyroby novych heterocyklickych sloucenin
ATE29882T1 (de) Verfahren zur herstellung von substituierten pyrimidinonen und deren zwischenprodukte.
DK0579968T3 (da) 4-Iminoquinoliner, fremgangsmåde til deres fremstilling og deres anvendelse
DE68922899D1 (de) Verbindungen von Pyrimidin 2'-Methylidin Nukleosiden.
DE3770724D1 (de) Thiazolidin-4-one-derivate un deren saeure-additionssalze.
ATE12499T1 (de) Gegebenenfalls n-substituierte amino-desoxy1.4;3.6-dianhydro-hexit-derivate, verfahren zu ihrer herstellung und deren verwendung.
RU96121584A (ru) Модифицированные нуклеозид-5'-трифосфаты как ингибиторы или субстраты днк- полимераз и антивирусные агенты
MY102464A (en) Antitumor agent
KR870010040A (ko) N-(2-피리미디닐) 피페라지닐 부틸 아자스피로 데칸디온의 제조방법
TH14702A (th) 2'-ดีออกซิ-2', 2'-ไดฟลูออโร พิวริน นิวคลีโอสีด(ที่ถูกแทนที่ที่ตำแหน่ง 2, 6, 8) ที่มีการออกฤทธิ์ต่อต้านไวรัสและต่อต้านมะเร็ง และสารประกอบตัวกลาง
BE901727A (fr) Derives d'hexahydroazepino 3, 4-d imidazoles.
FI824330L (fi) 1-(3-nitrofenyl)pyrido/2,3-d/pyrimidin-2,4(1h,3h)dioner och 1-(3-nitrofenyl)kinazolin-2,4-(1h,3h)dioner saosom genom huden verkande laekemedel
IT8453846U1 (it) Attrezzo didattico per la corretta scrittura manuale di segni e note musicali
KR880013921A (ko) 4,4-디메틸-l-[4-[4-(2-피리미디닐)-l-피페라지닐]부틸]-2,6-피페리딘 디온의 제조방법