AU581919B2 - Process for the preparation of cis, endooctahydrocyclopenta (b) pyrrole-2-carboxylate - Google Patents

Process for the preparation of cis, endooctahydrocyclopenta (b) pyrrole-2-carboxylate

Info

Publication number
AU581919B2
AU581919B2 AU46718/85A AU4671885A AU581919B2 AU 581919 B2 AU581919 B2 AU 581919B2 AU 46718/85 A AU46718/85 A AU 46718/85A AU 4671885 A AU4671885 A AU 4671885A AU 581919 B2 AU581919 B2 AU 581919B2
Authority
AU
Australia
Prior art keywords
endooctahydrocyclopenta
pyrrole
carboxylate
cis
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU46718/85A
Other languages
English (en)
Other versions
AU4671885A (en
Inventor
Elijah Herman Gold
Bernard Ray Neustadt
Elizabeth Melva Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/635,390 external-priority patent/US4587258A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of AU4671885A publication Critical patent/AU4671885A/en
Application granted granted Critical
Publication of AU581919B2 publication Critical patent/AU581919B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pyrrole Compounds (AREA)
AU46718/85A 1984-07-30 1985-07-26 Process for the preparation of cis, endooctahydrocyclopenta (b) pyrrole-2-carboxylate Ceased AU581919B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US635390 1984-07-30
US06/635,390 US4587258A (en) 1980-10-23 1984-07-30 Angiotensin-converting enzyme inhibitors

Publications (2)

Publication Number Publication Date
AU4671885A AU4671885A (en) 1986-02-25
AU581919B2 true AU581919B2 (en) 1989-03-09

Family

ID=24547612

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46718/85A Ceased AU581919B2 (en) 1984-07-30 1985-07-26 Process for the preparation of cis, endooctahydrocyclopenta (b) pyrrole-2-carboxylate

Country Status (7)

Country Link
EP (1) EP0190224A1 (ja)
JP (1) JPS61502818A (ja)
AU (1) AU581919B2 (ja)
CA (1) CA1244041A (ja)
DK (1) DK140886A (ja)
WO (1) WO1986000896A1 (ja)
ZA (1) ZA855659B (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
DE3518514A1 (de) * 1985-05-23 1986-11-27 Hoechst Ag, 6230 Frankfurt Neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
DE3839127A1 (de) * 1988-11-19 1990-05-23 Hoechst Ag Pyrrolidon-2-carbonsaeure-derivate mit psychotroper wirkung
US5629345A (en) * 1993-07-23 1997-05-13 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) * 1993-07-23 1999-10-12 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
GB9716657D0 (en) 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
GB9803226D0 (en) 1998-02-17 1998-04-08 Zeneca Ltd Chemical compounds
GB9902459D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902452D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902461D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902455D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902453D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB0000625D0 (en) 2000-01-13 2000-03-01 Zeneca Ltd Chemical compounds
WO2005049568A1 (en) * 2003-11-24 2005-06-02 Potluri Ramesh Babu A process for industrially viable preparation of (s,s,s) phenylmethyl-2-azabicyclo-[3.3.0]-octane-3-carboxylate tosylate
RU2361862C2 (ru) 2003-12-29 2009-07-20 Сепракор Инк. Пиррольные и пиразольные ингибиторы daao
US8053603B2 (en) 2006-01-06 2011-11-08 Sunovion Pharmaceuticals Inc. Tetralone-based monoamine reuptake inhibitors
KR101294014B1 (ko) 2006-01-06 2013-08-09 선오비온 파마슈티컬스 인코포레이티드 모노아민 재흡수 저해제로서의 시클로알킬아민
PT2816024T (pt) 2006-03-31 2017-10-20 Sunovion Pharmaceuticals Inc Aminas quirais
US20090099248A1 (en) 2007-01-18 2009-04-16 Sepracor Inc. Inhibitors of d-amino acid oxidase
US7902252B2 (en) 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
RU2470011C2 (ru) 2007-05-31 2012-12-20 Сепракор Инк. Циклоалкиламины, содержащие в качестве заместителя фенил, как ингибиторы обратного захвата моноаминов

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU563644B2 (en) * 1983-07-21 1987-07-16 E.R. Squibb & Sons, Inc. Hydroxy substituted peptides
AU566589B2 (en) * 1983-01-31 1987-10-22 Aventis Pharma Deutschland Gmbh Resolution of optical isomers of bicycle pyrrollidine compounds and the products in peptide synthesis
AU566490B2 (en) * 1983-06-06 1987-10-22 Adir Et Compagnie Isoindoledicarboxylic acid derivatives, their preparation and pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19575012I2 (de) * 1980-10-23 2002-01-24 Schering Corp Carboxyalkyl-Dipeptide Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
GR78413B (ja) * 1981-12-29 1984-09-27 Hoechst Ag
IE54551B1 (en) * 1982-01-22 1989-11-22 Ici Plc Amide derivatives
DE3211676A1 (de) * 1982-03-30 1983-10-06 Hoechst Ag Neue derivate von cycloalka (c) pyrrol-carbonsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue cycloalka (c) pyrrol-carbonsaeuren als zwischenstufen und verfahren zu deren herstellung
DE3302125A1 (de) * 1983-01-22 1984-07-26 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung
DE3315464A1 (de) * 1983-04-28 1984-10-31 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU566589B2 (en) * 1983-01-31 1987-10-22 Aventis Pharma Deutschland Gmbh Resolution of optical isomers of bicycle pyrrollidine compounds and the products in peptide synthesis
AU566490B2 (en) * 1983-06-06 1987-10-22 Adir Et Compagnie Isoindoledicarboxylic acid derivatives, their preparation and pharmaceutical compositions
AU563644B2 (en) * 1983-07-21 1987-07-16 E.R. Squibb & Sons, Inc. Hydroxy substituted peptides

Also Published As

Publication number Publication date
DK140886D0 (da) 1986-03-26
AU4671885A (en) 1986-02-25
CA1244041A (en) 1988-11-01
DK140886A (da) 1986-03-26
ZA855659B (en) 1987-03-25
WO1986000896A1 (en) 1986-02-13
EP0190224A1 (en) 1986-08-13
JPS61502818A (ja) 1986-12-04

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