ZA855659B - Novel process for the preparation of cis,endo-octahydrocyclopenta(b)pyrrole-2-carboxylate - Google Patents

Novel process for the preparation of cis,endo-octahydrocyclopenta(b)pyrrole-2-carboxylate

Info

Publication number
ZA855659B
ZA855659B ZA855659A ZA855659A ZA855659B ZA 855659 B ZA855659 B ZA 855659B ZA 855659 A ZA855659 A ZA 855659A ZA 855659 A ZA855659 A ZA 855659A ZA 855659 B ZA855659 B ZA 855659B
Authority
ZA
South Africa
Prior art keywords
octahydrocyclopenta
endo
pyrrole
carboxylate
cis
Prior art date
Application number
ZA855659A
Other languages
English (en)
Inventor
Elijah Herman Gold
Bernard Ray Neustadt
Elizabeth Melva Smith
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/635,390 external-priority patent/US4587258A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA855659B publication Critical patent/ZA855659B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pyrrole Compounds (AREA)
ZA855659A 1984-07-30 1985-07-26 Novel process for the preparation of cis,endo-octahydrocyclopenta(b)pyrrole-2-carboxylate ZA855659B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/635,390 US4587258A (en) 1980-10-23 1984-07-30 Angiotensin-converting enzyme inhibitors

Publications (1)

Publication Number Publication Date
ZA855659B true ZA855659B (en) 1987-03-25

Family

ID=24547612

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA855659A ZA855659B (en) 1984-07-30 1985-07-26 Novel process for the preparation of cis,endo-octahydrocyclopenta(b)pyrrole-2-carboxylate

Country Status (7)

Country Link
EP (1) EP0190224A1 (xx)
JP (1) JPS61502818A (xx)
AU (1) AU581919B2 (xx)
CA (1) CA1244041A (xx)
DK (1) DK140886A (xx)
WO (1) WO1986000896A1 (xx)
ZA (1) ZA855659B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
DE3518514A1 (de) * 1985-05-23 1986-11-27 Hoechst Ag, 6230 Frankfurt Neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
DE3839127A1 (de) * 1988-11-19 1990-05-23 Hoechst Ag Pyrrolidon-2-carbonsaeure-derivate mit psychotroper wirkung
US5629345A (en) * 1993-07-23 1997-05-13 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) * 1993-07-23 1999-10-12 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
GB9716657D0 (en) 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
GB9803226D0 (en) 1998-02-17 1998-04-08 Zeneca Ltd Chemical compounds
GB9902459D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902461D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902452D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902455D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902453D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB0000625D0 (en) 2000-01-13 2000-03-01 Zeneca Ltd Chemical compounds
WO2005049568A1 (en) * 2003-11-24 2005-06-02 Potluri Ramesh Babu A process for industrially viable preparation of (s,s,s) phenylmethyl-2-azabicyclo-[3.3.0]-octane-3-carboxylate tosylate
PL380887A1 (pl) 2003-12-29 2007-04-02 Sepracor Inc. Pirolowe i pirazolowe inhibitory DAAO
JP5438975B2 (ja) 2006-01-06 2014-03-12 サノビオン ファーマシューティカルズ インク テトラロン系モノアミン再取り込み阻害剤
ES2594156T3 (es) 2006-01-06 2016-12-16 Sunovion Pharmaceuticals Inc. Cicloalquilaminas como inhibidores de la recaptación de monoaminas
WO2007115185A2 (en) 2006-03-31 2007-10-11 Sepracor Inc. Preparation of chiral amides and amines
WO2008089453A2 (en) 2007-01-18 2008-07-24 Sepracor Inc. Inhibitors of d-amino acid oxidase
US7902252B2 (en) 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
NZ580429A (en) 2007-05-31 2012-04-27 Sepracor Inc Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU88621I2 (fr) * 1980-10-23 1995-09-01 Schering Corp Sandopril
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
GR78413B (xx) * 1981-12-29 1984-09-27 Hoechst Ag
IE54551B1 (en) * 1982-01-22 1989-11-22 Ici Plc Amide derivatives
DE3211676A1 (de) * 1982-03-30 1983-10-06 Hoechst Ag Neue derivate von cycloalka (c) pyrrol-carbonsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue cycloalka (c) pyrrol-carbonsaeuren als zwischenstufen und verfahren zu deren herstellung
DE3302125A1 (de) * 1983-01-22 1984-07-26 Boehringer Ingelheim KG, 6507 Ingelheim Aminosaeure-derivate, verfahren zu ihrer herstellung und verwendung
HU191120B (en) * 1983-01-31 1987-01-28 Hoechts Ag,De Process for raceme separation of optically active byciclic imino-alpha-carbonic acid esthers
DE3315464A1 (de) * 1983-04-28 1984-10-31 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
FR2546886B2 (fr) * 1983-06-06 1986-05-16 Adir Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant
US4514391A (en) * 1983-07-21 1985-04-30 E. R. Squibb & Sons, Inc. Hydroxy substituted peptide compounds
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern

Also Published As

Publication number Publication date
AU4671885A (en) 1986-02-25
DK140886D0 (da) 1986-03-26
DK140886A (da) 1986-03-26
EP0190224A1 (en) 1986-08-13
CA1244041A (en) 1988-11-01
AU581919B2 (en) 1989-03-09
WO1986000896A1 (en) 1986-02-13
JPS61502818A (ja) 1986-12-04

Similar Documents

Publication Publication Date Title
ZA855659B (en) Novel process for the preparation of cis,endo-octahydrocyclopenta(b)pyrrole-2-carboxylate
PT81463A (en) Process for preparing novel 5-amino-4-hidroxyvalerylderivatives
PT79925B (en) Process for preparing 6-substituted-4-dialkylaminotetrahydrobenz<c,d>indoles
PL256373A1 (en) Process for preparing silibinin,free of isosilibin
HUT39168A (en) Process for preparing 1,3-oxazolidin-2-one-derivatives
GR80204B (en) Process for the preparation of 16-fluoro-16,17-didehydro prostanoids
DE3563351D1 (en) Process for the preparation of tetrachloro-benzo-1,4-dioxenes
HUT38942A (en) Process for preparing substituted 7-oxo-mitosanes
DE3568327D1 (en) Process for the preparation of 2,3,5-trimethylbenzoquinone
DE3476069D1 (en) Improved process for the preparation of polyhydroxybutadienes
EP0174375A4 (en) PRODUCTION PROCESS FOR N-ACYLPHENYLALANINE.
HUT37958A (en) Process for preparing /1s, 4r/-4-hydroxy-2-cyclopentenil-ester
DE3465083D1 (en) Process of preparation of 2-substituted-5-nitroso-4,6-diamino-pyrimidines
DE3565536D1 (en) Process for the preparation of 2-alkyl-4,5-dihydroxyimidazoles
AR242576A1 (es) Proceso para la preparacion de alfa-n-¡(hipoxantin-9-il)-pentiloxicarbonil¿-arginina.
DE3560069D1 (en) Process for preparing 2,6-dichloro-4-nitro-aniline
DE3361197D1 (en) Process for the preparation of 3-alkyl-2,5-dihydrofuran-2-ones
DE3361226D1 (en) Process for the preparation of 1-azolyl-3,3-dimethyl-1-phenoxy-butan-2-oles
HUT44564A (en) Novel process for preparing piroxicam-propharmakon
DE3560043D1 (en) Process for the preparation of 2-alkyl-4,4-diacyloxy-2-butenals
DE3660597D1 (en) Process for the preparation of 5-fluorotoluene-2,4-disulfochloride
EP0195738A3 (en) Process for the preparation of n,n -diisopropyl-2-benzothiazyl-sulfenamide
DE3565264D1 (en) Process for the manufacture of (ir,cis)-4-acetyl-6,6-dimethyl-3-oxa-bicyclo(3.1.0)hex-2-one
AU597439B2 (en) Process for the preparation of n-acyl-n-alkyl-2,6-dialkyl-3- chloroanilines
DE3566539D1 (en) Process for preparing 2,2,6,6-tetramethyl-4-oxopiperidine