AU547211B2 - Spiro-condensed system continuing four actero rings - Google Patents

Spiro-condensed system continuing four actero rings

Info

Publication number
AU547211B2
AU547211B2 AU69730/81A AU6973081A AU547211B2 AU 547211 B2 AU547211 B2 AU 547211B2 AU 69730/81 A AU69730/81 A AU 69730/81A AU 6973081 A AU6973081 A AU 6973081A AU 547211 B2 AU547211 B2 AU 547211B2
Authority
AU
Australia
Prior art keywords
compounds
chromic acid
actero
spiro
rings
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU69730/81A
Other languages
English (en)
Other versions
AU6973081A (en
Inventor
August J. Kempf
John G. Macconnell
Helmut H. Mrozik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU6973081A publication Critical patent/AU6973081A/en
Application granted granted Critical
Publication of AU547211B2 publication Critical patent/AU547211B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Veterinary Medicine (AREA)
  • Dentistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AU69730/81A 1980-05-02 1981-04-22 Spiro-condensed system continuing four actero rings Ceased AU547211B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US146725 1980-05-02
US06/146,725 US4289760A (en) 1980-05-02 1980-05-02 23-Keto derivatives of C-076 compounds

Publications (2)

Publication Number Publication Date
AU6973081A AU6973081A (en) 1981-11-05
AU547211B2 true AU547211B2 (en) 1985-10-10

Family

ID=22518711

Family Applications (1)

Application Number Title Priority Date Filing Date
AU69730/81A Ceased AU547211B2 (en) 1980-05-02 1981-04-22 Spiro-condensed system continuing four actero rings

Country Status (13)

Country Link
US (1) US4289760A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0040913B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5718684A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE8637T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU547211B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1168605A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3165016D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK193881A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES501777A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR74875B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ196897A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT72915B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA812908B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57139012A (en) * 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4333925A (en) * 1981-05-11 1982-06-08 Merck & Co., Inc. Derivatives of C-076 compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
US4510133A (en) * 1982-04-22 1985-04-09 Imperial Chemical Industries Plc Method for combating pests
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
US4582852A (en) * 1983-11-02 1986-04-15 Ciba-Geigy Corporation 14- and 15-hydroxy milbemycin derivatives for controlling plant and animal parasites
JPS60126289A (ja) * 1983-11-14 1985-07-05 Sankyo Co Ltd ミルベマイシン類の５−カ−ボネ−ト誘導体
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
US4547491A (en) * 1984-07-18 1985-10-15 Merck & Co., Inc. C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
IT1190285B (it) * 1985-04-30 1988-02-16 Glaxo Group Ltd Antibiotici macrolidi e procedimento per prepararli ed applicarli
ES8802229A1 (es) * 1985-04-30 1988-04-16 Glaxo Group Ltd Un procedimiento para preparar nuevos derivados lactonicos macrociclicos.
US4789684A (en) * 1985-05-02 1988-12-06 Merck & Co., Inc. Anthelmintic fermentation products of microorganisms
ES8605582A1 (es) * 1985-12-11 1986-03-16 Antibioticos Sa Un procedimiento para la preparacion de avermectinas
AU597930B2 (en) * 1986-01-23 1990-06-14 Glaxo Group Limited Macrolide antibiotics and their preparation
GB8606108D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Chemical compounds
CA1296328C (en) * 1986-03-12 1992-02-25 Derek R. Sutherland Macrolide compounds
NZ219574A (en) * 1986-03-12 1994-03-25 American Cyanamid Co Substitut A milbemycin, a strain of streptomyces capable of producing it, and pesticidal compositions
CA1296329C (en) * 1986-06-06 1992-02-25 Derek R. Sutherland Macrolide compounds
US4916154A (en) * 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
US4849446A (en) * 1986-09-12 1989-07-18 American Cyanamid Company 23-imino derivatives of 23-keto compounds
EP0260537A1 (en) * 1986-09-12 1988-03-23 American Cyanamid Company 13-Deoxy-23-oxo(keto) and 23-imino derivatives of 13-deoxy C-076-aglycone compounds
EP0259779B1 (en) * 1986-09-12 1994-08-10 American Cyanamid Company 23-Oxo (Keto) and 23-imino Derivatives of LL-F28249 Compounds
US4886784A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Novel 23-imino derivatives of 23-keto compounds
US4877888A (en) * 1986-09-12 1989-10-31 American Cyanamid Company 13-deoxy-23-imino derivatives of 13-deoxy C-076-aglycone compounds
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4906619A (en) * 1988-07-22 1990-03-06 Merck & Co., Inc. Alkyl avermectin derivatives
US5428034A (en) * 1988-09-02 1995-06-27 Sankyo Co., Ltd. Milbemycin derivatives, their preparation and their use
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
JP2622197B2 (ja) * 1990-03-01 1997-06-18 三共株式会社 １３−エーテル置換ミルベマイシン誘導体
US5169839A (en) * 1990-05-11 1992-12-08 Merck & Co., Inc. Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections
US5188944A (en) * 1990-06-22 1993-02-23 Merck & Co., Inc. Process for the glycosylation of avermectin agylcones
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5240915A (en) * 1991-10-15 1993-08-31 Merck & Co., Inc. Avermectin derivatives
US5276033A (en) * 1991-12-18 1994-01-04 Sankyo Company, Limited 13-(substituted thio)acetoxymilbemycin derivatives, their preparation and their agrochemical uses
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
IL107810A0 (en) * 1992-12-17 1994-02-27 Exxon Chemical Patents Inc Functionalized polymers and processes for the preparation thereof
NZ299460A (en) * 1995-09-29 1997-12-19 Sankyo Co 13-substituted milbemycin 5-oxime derivatives; veterinary pesticides
DE60116615T2 (de) 2000-04-27 2006-09-07 Sankyo Lifetech Co.Ltd. 13-substituierte milbemycinderivate, ihre herstellung und ihre verwendung gegen insekten und andere schadorganismen

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4172940A (en) * 1977-10-03 1979-10-30 Merck & Co., Inc. Purification of C-076 compounds by single column chromatography
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
IL56149A (en) * 1977-12-19 1989-09-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds,their preparation and method for the treatment of parasitic infections in animals therewith
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds

Also Published As

Publication number Publication date
GR74875B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-07-12
ES8207544A1 (es) 1982-09-16
JPS5718684A (en) 1982-01-30
DK193881A (da) 1981-11-03
PT72915A (en) 1981-05-01
EP0040913B1 (en) 1984-07-25
PT72915B (en) 1983-02-16
EP0040913A1 (en) 1981-12-02
US4289760A (en) 1981-09-15
ZA812908B (en) 1982-12-29
ATE8637T1 (de) 1984-08-15
NZ196897A (en) 1984-09-28
CA1168605A (en) 1984-06-05
AU6973081A (en) 1981-11-05
DE3165016D1 (en) 1984-08-30
JPH0254358B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1990-11-21
ES501777A0 (es) 1982-09-16

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