AU5319396A - Thiono triester modified antisense oligodeoxynucleotide phosphorothioates - Google Patents

Thiono triester modified antisense oligodeoxynucleotide phosphorothioates

Info

Publication number
AU5319396A
AU5319396A AU53193/96A AU5319396A AU5319396A AU 5319396 A AU5319396 A AU 5319396A AU 53193/96 A AU53193/96 A AU 53193/96A AU 5319396 A AU5319396 A AU 5319396A AU 5319396 A AU5319396 A AU 5319396A
Authority
AU
Australia
Prior art keywords
modified antisense
antisense oligodeoxynucleotide
thiono
oligodeoxynucleotide phosphorothioates
triester modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU53193/96A
Inventor
Jimmy X Tang
Jin Yan Tang
Zhaoda Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aceragen Inc
Original Assignee
Hybridon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybridon Inc filed Critical Hybridon Inc
Publication of AU5319396A publication Critical patent/AU5319396A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
AU53193/96A 1995-03-23 1996-03-22 Thiono triester modified antisense oligodeoxynucleotide phosphorothioates Abandoned AU5319396A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40916995A 1995-03-23 1995-03-23
US409169 1995-03-23
PCT/US1996/003843 WO1996029337A1 (en) 1995-03-23 1996-03-22 Thiono triester modified antisense oligodeoxynucleotide phosphorothioates

Publications (1)

Publication Number Publication Date
AU5319396A true AU5319396A (en) 1996-10-08

Family

ID=23619328

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53193/96A Abandoned AU5319396A (en) 1995-03-23 1996-03-22 Thiono triester modified antisense oligodeoxynucleotide phosphorothioates

Country Status (4)

Country Link
JP (1) JPH11502818A (en)
AU (1) AU5319396A (en)
CA (1) CA2216284A1 (en)
WO (1) WO1996029337A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU734022B2 (en) * 1997-05-01 2001-05-31 University Of Sydney, The Nucleic acid molecules specific for bacterial antigens and uses thereof

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2215097A (en) * 1996-03-14 1997-10-01 Hybridon, Inc. Selected oligonucleotides with anti-cytomegalovirus activity
US6776986B1 (en) 1996-06-06 2004-08-17 Novartis Ag Inhibition of HIV-1 replication by antisense RNA expression
EP0923596A2 (en) * 1996-07-31 1999-06-23 Gilead Sciences, Inc. Lipophilic oligonucleotide analogs
WO1998007734A1 (en) * 1996-08-21 1998-02-26 Hybridon, Inc. Oligonucleotide prodrugs
EP1129064B1 (en) 1998-11-12 2008-01-09 Invitrogen Corporation Transfection reagents
WO2006065751A2 (en) * 2004-12-13 2006-06-22 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Cpg oligonucleotide prodrugs, compositions thereof and associated therapeutic methods
EP3169310A1 (en) 2014-07-15 2017-05-24 Life Technologies Corporation Compositions with lipid aggregates and methods for efficient delivery of molecules to cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991004983A1 (en) * 1989-10-05 1991-04-18 University Patents, Inc. Nucleoside and polynucleotide thiophosphoramidite and phosphorodithioate compounds and processes
AU678769B2 (en) * 1992-07-27 1997-06-12 Hybridon, Inc. Oligonucleotide alkylphosphonothioates
ES2100051T3 (en) * 1993-01-08 1997-06-01 Hybridon Inc SYNTHESIS OF DIMER BLOCKS AND THEIR USE IN THE ASSEMBLY OF OLIGONUCLEOTIDES.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU734022B2 (en) * 1997-05-01 2001-05-31 University Of Sydney, The Nucleic acid molecules specific for bacterial antigens and uses thereof

Also Published As

Publication number Publication date
CA2216284A1 (en) 1996-09-26
WO1996029337A1 (en) 1996-09-26
JPH11502818A (en) 1999-03-09

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