AU3126595A - Antisense oligonucleotides of pleiotrophin - Google Patents

Antisense oligonucleotides of pleiotrophin

Info

Publication number
AU3126595A
AU3126595A AU31265/95A AU3126595A AU3126595A AU 3126595 A AU3126595 A AU 3126595A AU 31265/95 A AU31265/95 A AU 31265/95A AU 3126595 A AU3126595 A AU 3126595A AU 3126595 A AU3126595 A AU 3126595A
Authority
AU
Australia
Prior art keywords
pleiotrophin
antisense oligonucleotides
antisense
oligonucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU31265/95A
Inventor
Kenneth J. Colley
Anton Wellstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Georgetown University
Original Assignee
Georgetown University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Georgetown University filed Critical Georgetown University
Publication of AU3126595A publication Critical patent/AU3126595A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates
AU31265/95A 1994-07-18 1995-07-18 Antisense oligonucleotides of pleiotrophin Abandoned AU3126595A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27633094A 1994-07-18 1994-07-18
US276330 1994-07-18
PCT/US1995/008781 WO1996002257A1 (en) 1994-07-18 1995-07-18 Antisense oligonucleotides of pleiotrophin

Publications (1)

Publication Number Publication Date
AU3126595A true AU3126595A (en) 1996-02-16

Family

ID=23056211

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31265/95A Abandoned AU3126595A (en) 1994-07-18 1995-07-18 Antisense oligonucleotides of pleiotrophin

Country Status (4)

Country Link
JP (1) JPH10506003A (en)
AU (1) AU3126595A (en)
CA (1) CA2195450A1 (en)
WO (1) WO1996002257A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000076133A (en) * 1997-03-12 2000-12-26 나까야마 유 Preventive and therapeutic compositions for drug induced nephropathy and hepatitis
CN1379681A (en) * 1998-04-17 2002-11-13 安乔格尼克斯公司 therapeutic angiogenic factors and methods for their use
WO2000010608A1 (en) 1998-08-24 2000-03-02 Meiji Milk Products Co., Ltd. Preventives/remedies for arteriosclerosis and post-ptca reangiostenosis
US7141384B1 (en) 1998-10-06 2006-11-28 Georgetown University Detection of pleiotrophin
JP2002526777A (en) * 1998-10-06 2002-08-20 ジョージタウン ユニバーシティ Pleiotrophin detection method
AU2055300A (en) * 1998-12-18 2000-07-03 Scios Inc. Methods for detection and use of differentially expressed genes in disease states
US6709855B1 (en) 1998-12-18 2004-03-23 Scios, Inc. Methods for detection and use of differentially expressed genes in disease states
US6770264B2 (en) 2001-11-13 2004-08-03 Noville, Inc. Chewing gum compositions comprising diglycerol
CN100386435C (en) * 2005-12-19 2008-05-07 中国人民解放军军事医学科学院放射与辐射医学研究所 Small interfering RNA for suppressing multiple effect growth factor expression and its uses

Also Published As

Publication number Publication date
JPH10506003A (en) 1998-06-16
CA2195450A1 (en) 1996-02-01
WO1996002257A1 (en) 1996-02-01

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