AU524737B2 - Aminoglycosides derived from desoxystreptamine - Google Patents

Aminoglycosides derived from desoxystreptamine

Info

Publication number
AU524737B2
AU524737B2 AU50584/79A AU5058479A AU524737B2 AU 524737 B2 AU524737 B2 AU 524737B2 AU 50584/79 A AU50584/79 A AU 50584/79A AU 5058479 A AU5058479 A AU 5058479A AU 524737 B2 AU524737 B2 AU 524737B2
Authority
AU
Australia
Prior art keywords
formula
product
amino
tridesoxy
streptamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU50584/79A
Other languages
English (en)
Other versions
AU5058479A (en
Inventor
Jean-Claude Gasc
Claude Rettien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of AU5058479A publication Critical patent/AU5058479A/en
Application granted granted Critical
Publication of AU524737B2 publication Critical patent/AU524737B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AU50584/79A 1978-09-06 1979-09-05 Aminoglycosides derived from desoxystreptamine Ceased AU524737B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7825604 1978-09-06
FR7825604A FR2435481A1 (fr) 1978-09-06 1978-09-06 Nouveaux aminoglycosides derives de la desoxystreptamine et leurs sels, procede de preparation et application a titre de medicaments

Publications (2)

Publication Number Publication Date
AU5058479A AU5058479A (en) 1980-03-13
AU524737B2 true AU524737B2 (en) 1982-09-30

Family

ID=9212381

Family Applications (1)

Application Number Title Priority Date Filing Date
AU50584/79A Ceased AU524737B2 (en) 1978-09-06 1979-09-05 Aminoglycosides derived from desoxystreptamine

Country Status (11)

Country Link
US (1) US4242331A (enExample)
EP (1) EP0008965B1 (enExample)
JP (1) JPS5538378A (enExample)
AT (1) ATE969T1 (enExample)
AU (1) AU524737B2 (enExample)
CA (1) CA1133476A (enExample)
DE (1) DE2962697D1 (enExample)
FR (1) FR2435481A1 (enExample)
HU (1) HU180288B (enExample)
IE (1) IE49299B1 (enExample)
ZA (1) ZA794155B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1001869A3 (fr) * 1988-10-12 1990-04-03 Franz Legros Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine.
US5442047A (en) * 1991-12-04 1995-08-15 Schering Corporation Process for preparing isepamicin
IT1237490B (it) * 1989-09-22 1993-06-07 Chementecno S R L Monza Milano Procedimento per la sintesi della 1 n (s delta ammino alfa idrossibutirril)kamanycin a basato sul trattamento della 1 n (s delta benzilossicarbonilammino alfa idrossibutirril) 3,6' di n benzilossicarbonilkanamycin a con acido formico
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001208A (en) * 1972-10-06 1977-01-04 Zaidan Hojin Biseibutsu Kagaku Kenkyo Kai 1-N-[(S)-α-hydroxy-ω-aminoacyl]
CA1046512A (en) * 1974-03-19 1979-01-16 Peter J.L. Daniels Derivatives of diaminocyclitols and method for their preparation
FR2290908A1 (fr) * 1974-11-13 1976-06-11 Roussel Uclaf Nouveau derive aminoglycosidique et ses sels, leur procede de preparation et leur application comme medicaments
FR2318648A1 (fr) * 1975-07-23 1977-02-18 Roussel Uclaf Nouveau derive de la desoxystreptamine et des sels, leur procede de preparation et leur application comme medicaments
FR2358156A1 (fr) * 1976-03-31 1978-02-10 Roussel Uclaf Nouvel analogue de la desoxystreptamine et ses sels, leur procede de preparation et leur application comme medicaments
US4146617A (en) * 1976-07-15 1979-03-27 Roussel Uclaf Desoxystreptamine derivatives, salts, pharmaceutical compositions and method of use

Also Published As

Publication number Publication date
JPS6340196B2 (enExample) 1988-08-10
HU180288B (en) 1983-02-28
AU5058479A (en) 1980-03-13
EP0008965B1 (fr) 1982-05-05
ZA794155B (en) 1980-08-27
IE791693L (en) 1980-03-06
US4242331A (en) 1980-12-30
IE49299B1 (en) 1985-09-18
CA1133476A (fr) 1982-10-12
ATE969T1 (de) 1982-05-15
DE2962697D1 (en) 1982-06-24
EP0008965A3 (en) 1980-04-02
EP0008965A2 (fr) 1980-03-19
JPS5538378A (en) 1980-03-17
FR2435481B1 (enExample) 1981-07-24
FR2435481A1 (fr) 1980-04-04

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