AU5156193A - Flow restrictor-separation device - Google Patents
Flow restrictor-separation deviceInfo
- Publication number
- AU5156193A AU5156193A AU51561/93A AU5156193A AU5156193A AU 5156193 A AU5156193 A AU 5156193A AU 51561/93 A AU51561/93 A AU 51561/93A AU 5156193 A AU5156193 A AU 5156193A AU 5156193 A AU5156193 A AU 5156193A
- Authority
- AU
- Australia
- Prior art keywords
- tube
- flow
- chamber
- separation device
- restriction channel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000926 separation method Methods 0.000 title claims description 126
- 239000012530 fluid Substances 0.000 claims description 47
- 239000007788 liquid Substances 0.000 claims description 33
- 238000000034 method Methods 0.000 claims description 28
- 238000004891 communication Methods 0.000 claims description 25
- 230000003287 optical effect Effects 0.000 claims description 6
- 238000005191 phase separation Methods 0.000 claims description 5
- 238000000638 solvent extraction Methods 0.000 claims description 4
- 239000000523 sample Substances 0.000 description 36
- 210000004369 blood Anatomy 0.000 description 34
- 239000008280 blood Substances 0.000 description 34
- 210000002966 serum Anatomy 0.000 description 14
- 239000000463 material Substances 0.000 description 13
- 230000001413 cellular effect Effects 0.000 description 12
- 239000000306 component Substances 0.000 description 10
- 210000004027 cell Anatomy 0.000 description 9
- 238000004519 manufacturing process Methods 0.000 description 6
- 238000007789 sealing Methods 0.000 description 6
- UQMRAFJOBWOFNS-UHFFFAOYSA-N butyl 2-(2,4-dichlorophenoxy)acetate Chemical compound CCCCOC(=O)COC1=CC=C(Cl)C=C1Cl UQMRAFJOBWOFNS-UHFFFAOYSA-N 0.000 description 5
- 210000000601 blood cell Anatomy 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 4
- 239000000499 gel Substances 0.000 description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 229920000642 polymer Polymers 0.000 description 4
- 239000012503 blood component Substances 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000013536 elastomeric material Substances 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000003566 sealing material Substances 0.000 description 3
- 229920003345 Elvax® Polymers 0.000 description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 2
- 239000005977 Ethylene Substances 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 238000005345 coagulation Methods 0.000 description 2
- 230000015271 coagulation Effects 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 230000013011 mating Effects 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 241001312297 Selar Species 0.000 description 1
- 229920003365 Selar® Polymers 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 229920001169 thermoplastic Polymers 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5021—Test tubes specially adapted for centrifugation purposes
- B01L3/50215—Test tubes specially adapted for centrifugation purposes using a float to separate phases
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Ecology (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Centrifugal Separators (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Steering Control In Accordance With Driving Conditions (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US877496 | 1992-05-01 | ||
| US07/877,496 US5282981A (en) | 1992-05-01 | 1992-05-01 | Flow restrictor-separation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU5156193A true AU5156193A (en) | 1993-11-29 |
Family
ID=25370098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU51561/93A Abandoned AU5156193A (en) | 1992-05-01 | 1993-04-23 | Flow restrictor-separation device |
Country Status (8)
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5271852A (en) * | 1992-05-01 | 1993-12-21 | E. I. Du Pont De Nemours And Company | Centrifugal methods using a phase-separation tube |
| US5389265A (en) * | 1993-06-02 | 1995-02-14 | E. I. Du Pont De Nemours And Company | Phase-separation tube |
| US5780248A (en) | 1993-07-15 | 1998-07-14 | Ortho Diagnostic Systems, Inc. | Foil sealed cassette for agglutination reactions and liner therefor |
| US5431814A (en) * | 1993-10-22 | 1995-07-11 | Jorgensen; Glen | Centrifugal filter apparatus and method |
| USD363353S (en) | 1993-10-27 | 1995-10-17 | Du Pont Canada Inc. | Axial spin centrifuge |
| GR1003213B (el) * | 1996-02-02 | 1999-09-22 | Ortho Diagnostic Systems Inc. | Αντιδραση οροσυγκολλησης και δοχειο διαχωρισμου |
| US5785925A (en) * | 1996-08-29 | 1998-07-28 | Saigene Corporation | Centrifuge tube phase separation plug |
| US5762881A (en) * | 1996-10-29 | 1998-06-09 | Bohdan Automation, Inc. | Apparatus for multiple, simultaneous synthesis of organic compounds |
| US6979307B2 (en) * | 1997-06-24 | 2005-12-27 | Cascade Medical Enterprises Llc | Systems and methods for preparing autologous fibrin glue |
| US7745106B2 (en) * | 1997-06-24 | 2010-06-29 | Cascade Medical Enterprises, Llc | Methods and devices for separating liquid components |
| US6406671B1 (en) * | 1998-12-05 | 2002-06-18 | Becton, Dickinson And Company | Device and method for separating components of a fluid sample |
| US7001774B1 (en) * | 1999-03-05 | 2006-02-21 | Microliter Analytical Supplies, Inc. | Sample collection and processing device |
| AU8033200A (en) * | 1999-08-25 | 2001-03-19 | Leland L. Bass | Centrifuge tube apparatus |
| US7947236B2 (en) | 1999-12-03 | 2011-05-24 | Becton, Dickinson And Company | Device for separating components of a fluid sample |
| US6803022B2 (en) * | 1999-12-06 | 2004-10-12 | Becton, Dickinson And Company | Device and method for separating components of a fluid sample |
| US7077273B2 (en) | 2000-04-28 | 2006-07-18 | Harvest Technologies Corporation | Blood component separator disk |
| AU2003298519A1 (en) * | 2002-06-27 | 2004-06-23 | Roberto Beretta | Methods for preparing a solid-fibrin web |
| US7220593B2 (en) | 2002-10-03 | 2007-05-22 | Battelle Memorial Institute | Buffy coat separator float system and method |
| US20130084579A1 (en) * | 2002-10-03 | 2013-04-04 | Battelle Memorial Institute | Drug susceptibility using rare cell detection system |
| WO2011126866A1 (en) * | 2010-03-30 | 2011-10-13 | Battelle Memorial Institute | Buffy coat separator float systems and methods |
| US20050065454A1 (en) * | 2003-09-22 | 2005-03-24 | Becton, Dickinson And Company | Non-evacuated blood collection tube |
| AU2005309950B2 (en) | 2004-11-24 | 2011-04-21 | Battelle Memorial Institute | Optical system for cell imaging |
| US20070003449A1 (en) * | 2005-06-10 | 2007-01-04 | Mehdi Hatamian | Valve for facilitating and maintaining fluid separation |
| US7798021B2 (en) * | 2006-01-12 | 2010-09-21 | Gamble Kimberly R | Method and apparatus for sample processing and injection |
| US8667832B2 (en) * | 2008-03-04 | 2014-03-11 | Cleveland State University | Method and system for particle settling velocity measurement |
| BRPI0915953B1 (pt) | 2008-07-21 | 2021-04-13 | Becton, Dickinson And Company | Separador mecânico, montagem de separação e método de separar |
| MX2011000799A (es) | 2008-07-21 | 2011-03-01 | Becton Dickinson Co | Dispositivo de separacion de fases por densidad. |
| AU2009274099B2 (en) | 2008-07-21 | 2012-06-28 | Becton, Dickinson And Company | Density phase separation device |
| EP2429712A1 (en) | 2009-05-01 | 2012-03-21 | Trustees of Boston University | Disposal separator/concentrator device and method of use |
| CN105214750B (zh) | 2009-05-15 | 2017-07-28 | 贝克顿·迪金森公司 | 密度相分离装置 |
| GB201113017D0 (en) | 2011-07-28 | 2011-09-14 | Ge Healthcare Bio Sciences Ab | Improvements in and relating to fluid sample holders |
| GB201113009D0 (en) | 2011-07-28 | 2011-09-14 | Ge Healthcare Bio Sciences Ab | Improvements in and relating to fluid sample holders |
| US20140349828A1 (en) * | 2013-05-01 | 2014-11-27 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| US9956555B2 (en) | 2012-11-30 | 2018-05-01 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| US9539570B2 (en) * | 2012-11-30 | 2017-01-10 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| US9533303B2 (en) * | 2012-11-30 | 2017-01-03 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| US9513291B2 (en) | 2012-11-30 | 2016-12-06 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| US10054524B2 (en) * | 2012-11-30 | 2018-08-21 | Rarecyte, Inc. | Apparatus, system and method for collecting a target material |
| US9217697B2 (en) | 2012-11-30 | 2015-12-22 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| US9039999B2 (en) * | 2012-11-30 | 2015-05-26 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| US9945839B2 (en) * | 2012-11-30 | 2018-04-17 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| WO2014085456A1 (en) * | 2012-11-30 | 2014-06-05 | Rarecyte, Inc. | Apparatus, system, and method for collecting a target material |
| US20140263062A1 (en) | 2013-03-14 | 2014-09-18 | Fresenius Medical Care Holdings, Inc. | Universal portable machine for online hemodiafiltration using regenerated dialysate |
| KR101585857B1 (ko) * | 2014-05-23 | 2016-01-15 | 주식회사 라온 | Prp 추출키트 |
| US9694359B2 (en) | 2014-11-13 | 2017-07-04 | Becton, Dickinson And Company | Mechanical separator for a biological fluid |
| EP3273217B1 (en) * | 2015-03-17 | 2019-10-16 | Micro Blood Science Inc. | Sample collection and separation device |
| CN109414694A (zh) * | 2016-06-03 | 2019-03-01 | 瑞尔赛特股份有限公司 | 用于收集靶物质的设备、系统和方法 |
| KR101894966B1 (ko) * | 2017-03-30 | 2018-09-04 | 신현순 | 원심분리용 용기 |
| US12226084B2 (en) * | 2020-07-01 | 2025-02-18 | Idexx Laboratories, Inc. | Collection device and method |
| US11612692B1 (en) | 2021-10-29 | 2023-03-28 | Thomas C. Kuracina | Method and apparatus to reduce the deadspace in syringes and small-bore devices |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3468474A (en) * | 1966-07-07 | 1969-09-23 | Arvid W Shoblom | Centrifuge accessory |
| US3741400A (en) * | 1970-06-15 | 1973-06-26 | J Dick | Blood sample container |
| DE2115032C3 (de) * | 1971-03-29 | 1975-05-07 | Kernforschungsanlage Juelich Gmbh, 5170 Juelich | Vorrichtung zum Trennen zweier Phasen bei der Flüssig-Flüssig-Extraktion in einer Zentrifuge |
| US3849072A (en) * | 1972-04-25 | 1974-11-19 | Becton Dickinson Co | Plasma separator |
| US3813031A (en) * | 1972-08-02 | 1974-05-28 | Atomic Energy Commission | Rotor having sample holding means |
| US3852194A (en) * | 1972-12-11 | 1974-12-03 | Corning Glass Works | Apparatus and method for fluid collection and partitioning |
| US4038788A (en) * | 1973-01-16 | 1977-08-02 | Willem Maria August Claessens | Sliding roof |
| US4001122A (en) * | 1973-08-22 | 1977-01-04 | Telan Corporation | Method and device for separating blood components |
| US3864089A (en) * | 1973-12-10 | 1975-02-04 | Atomic Energy Commission | Multiple-sample rotor assembly for blood fraction preparation |
| US3941699A (en) * | 1974-02-27 | 1976-03-02 | Becton, Dickinson And Company | Plasma separator with centrifugal valve |
| US3957654A (en) * | 1974-02-27 | 1976-05-18 | Becton, Dickinson And Company | Plasma separator with barrier to eject sealant |
| FR2274918A1 (fr) * | 1974-03-30 | 1976-01-09 | Sarstedt Kunststoff | Dispositif de filtrage pour la separation de fractions de sang |
| US3929646A (en) * | 1974-07-22 | 1975-12-30 | Technicon Instr | Serum separator and fibrin filter |
| US4049692A (en) * | 1974-12-16 | 1977-09-20 | Corning Glass Works | Stabilized blood separating composition |
| US3957197A (en) * | 1975-04-25 | 1976-05-18 | The United States Of America As Represented By The United States Energy Research And Development Administration | Centrifuge apparatus |
| CA1074273A (en) * | 1976-05-06 | 1980-03-25 | Sherwood Medical Industries Inc. | Phase separation device |
| US4152269A (en) * | 1977-02-01 | 1979-05-01 | Warner-Lambert Company | Collection and separation device |
| AT381466B (de) * | 1977-03-16 | 1986-10-27 | Ballies Uwe | Trennroehrchen fuer zentrifugaltrennung |
| US4202769A (en) * | 1977-06-16 | 1980-05-13 | Greenspan Donald J | Method for separating serum or plasma from the formed elements of blood |
| US4135883A (en) * | 1977-08-29 | 1979-01-23 | Bio-Dynamics Inc. | Blood analyzer system |
| US4151844A (en) * | 1977-11-11 | 1979-05-01 | Baxter Travenol Laboratories, Inc. | Method and apparatus for separating whole blood into its components and for automatically collecting one component |
| US4350593A (en) * | 1977-12-19 | 1982-09-21 | Becton, Dickinson And Company | Assembly, compositions and method for separating blood |
| SE412528B (sv) * | 1978-07-25 | 1980-03-10 | Separex Sa | Centrifugrotor och kollaberbar separationsbehallare |
| SE416617B (sv) * | 1979-03-28 | 1981-01-26 | Johansson A S | Anordning vid blodseparation genom utklemning av blodkomponenter ur en blodpase |
| US4284602A (en) * | 1979-12-10 | 1981-08-18 | Immutron, Inc. | Integrated fluid manipulator |
| US4283276A (en) * | 1980-02-29 | 1981-08-11 | E. I. Du Pont De Nemours And Company | Rotor for sedimentation field flow fractionation |
| US4285810A (en) * | 1980-02-29 | 1981-08-25 | E. I. Du Pont De Nemours And Company | Method and apparatus for field flow fractionation |
| US4269718A (en) * | 1980-05-05 | 1981-05-26 | The Institutes Of Medical Sciences | Process and device for centrifugal separation of platelets |
| US4417981A (en) * | 1981-05-04 | 1983-11-29 | Becton, Dickinson And Company | Blood phase separator device |
| US4550084A (en) * | 1982-01-15 | 1985-10-29 | Allied Corporation | Analysis system |
| US4443345A (en) * | 1982-06-28 | 1984-04-17 | Wells John R | Serum preparator |
| CH663722A5 (de) * | 1982-11-26 | 1988-01-15 | Sartorius Gmbh | Filtrationsgeraet. |
| DE3301113C2 (de) * | 1983-01-14 | 1985-01-10 | Fresenius AG, 6380 Bad Homburg | Verfahren und Vorrichtung für das Separieren von Medien |
| US4534465A (en) * | 1983-10-13 | 1985-08-13 | Coulter Electronics, Inc. | Cassette for supporting test tubes of different diameters and/or lengths |
| US4530691A (en) * | 1983-12-13 | 1985-07-23 | Baxter Travenol Laboratories, Inc. | Centrifuge with movable mandrel |
| CA1291098C (en) * | 1984-12-04 | 1991-10-22 | Albert August Luderer | Lymphocyte collection tube |
| US4639316A (en) * | 1984-12-14 | 1987-01-27 | Becton, Dickinson And Company | Automatic liquid component separator |
| US4724317A (en) * | 1985-12-05 | 1988-02-09 | Baxter Travenol Laboratories, Inc. | Optical data collection apparatus and method used with moving members |
| US4828716A (en) * | 1987-04-03 | 1989-05-09 | Andronic Devices, Ltd. | Apparatus and method for separating phases of blood |
| DE68923902T2 (de) * | 1988-05-11 | 1996-02-15 | Du Pont Canada | Gerät zur Trennung der Blutphasen. |
| US5061381A (en) * | 1990-06-04 | 1991-10-29 | Abaxis, Inc. | Apparatus and method for separating cells from biological fluids |
-
1992
- 1992-05-01 US US07/877,496 patent/US5282981A/en not_active Expired - Fee Related
-
1993
- 1993-04-23 WO PCT/CA1993/000173 patent/WO1993022673A1/en active IP Right Grant
- 1993-04-23 EP EP93911693A patent/EP0638171B1/en not_active Expired - Lifetime
- 1993-04-23 JP JP5518791A patent/JPH07505956A/ja active Pending
- 1993-04-23 DE DE69303367T patent/DE69303367T2/de not_active Expired - Fee Related
- 1993-04-23 CA CA002134468A patent/CA2134468A1/en not_active Abandoned
- 1993-04-23 AU AU51561/93A patent/AU5156193A/en not_active Abandoned
- 1993-05-01 TW TW082103423A patent/TW233258B/zh active
- 1993-10-13 US US08/135,246 patent/US5419835A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| TW233258B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1994-11-01 |
| JPH07505956A (ja) | 1995-06-29 |
| DE69303367T2 (de) | 1996-12-05 |
| CA2134468A1 (en) | 1993-11-11 |
| WO1993022673A1 (en) | 1993-11-11 |
| EP0638171B1 (en) | 1996-06-26 |
| US5282981A (en) | 1994-02-01 |
| DE69303367D1 (de) | 1996-08-01 |
| US5419835A (en) | 1995-05-30 |
| EP0638171A1 (en) | 1995-02-15 |
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