AU5102393A - Process for preparing certain pyrrolo(3,4- b)quinolines, certain 1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-3,14(4H,12H) -diones, and certain - Google Patents

Process for preparing certain pyrrolo(3,4- b)quinolines, certain 1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-3,14(4H,12H) -diones, and certain

Info

Publication number
AU5102393A
AU5102393A AU51023/93A AU5102393A AU5102393A AU 5102393 A AU5102393 A AU 5102393A AU 51023/93 A AU51023/93 A AU 51023/93A AU 5102393 A AU5102393 A AU 5102393A AU 5102393 A AU5102393 A AU 5102393A
Authority
AU
Australia
Prior art keywords
quinolin
process according
indolizino
compound
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU51023/93A
Other languages
English (en)
Inventor
Joseph M. Fortunak
Zhiping Zhuang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU5102393A publication Critical patent/AU5102393A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/14Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU51023/93A 1992-09-08 1993-09-08 Process for preparing certain pyrrolo(3,4- b)quinolines, certain 1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-3,14(4H,12H) -diones, and certain Abandoned AU5102393A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94149692A 1992-09-08 1992-09-08
US941496 1992-09-08
PCT/US1993/008434 WO1994005672A1 (en) 1992-09-08 1993-09-08 PROCESS FOR PREPARING CERTAIN PYRROLO[3,4- b]QUINOLINES, CERTAIN 1H-PYRANO[3',4':6,7]INDOLIZINO[1,2-b]QUINOLIN-3,14(4H,12H)-DIONES, AND CERTAIN 8-METHYL-7-(OXOPROPYL)-INDOLIZINO[1,2-b]QUINOLIN-9(11H)-ONES

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU28591/97A Division AU2859197A (en) 1992-09-08 1997-07-11 Process for preparing certain pyrrolo(3,4-b)quinolines, certain 1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-3,14 (4H,12H)-diones, and certain 8-methyl-7-(oxopropyl)- indolizino(1,2-b)quinolin-9(11H)-ones

Publications (1)

Publication Number Publication Date
AU5102393A true AU5102393A (en) 1994-03-29

Family

ID=25476581

Family Applications (2)

Application Number Title Priority Date Filing Date
AU51023/93A Abandoned AU5102393A (en) 1992-09-08 1993-09-08 Process for preparing certain pyrrolo(3,4- b)quinolines, certain 1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-3,14(4H,12H) -diones, and certain
AU28591/97A Abandoned AU2859197A (en) 1992-09-08 1997-07-11 Process for preparing certain pyrrolo(3,4-b)quinolines, certain 1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-3,14 (4H,12H)-diones, and certain 8-methyl-7-(oxopropyl)- indolizino(1,2-b)quinolin-9(11H)-ones

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU28591/97A Abandoned AU2859197A (en) 1992-09-08 1997-07-11 Process for preparing certain pyrrolo(3,4-b)quinolines, certain 1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-3,14 (4H,12H)-diones, and certain 8-methyl-7-(oxopropyl)- indolizino(1,2-b)quinolin-9(11H)-ones

Country Status (11)

Country Link
EP (1) EP0660835A4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH08501104A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR950702987A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1096297A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU5102393A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2144048A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9305517A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ255942A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW246674B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1994005672A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA936580B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6660861B1 (en) * 2003-03-27 2003-12-09 Council Of Scientific And Industrial Research Process for preparing Topotecan from 10-hydroxy-4-(S) camptothecin
CN2757510Y (zh) 2004-12-06 2006-02-08 鸿富锦精密工业(深圳)有限公司 散热器扣具
US7520313B2 (en) 2006-03-16 2009-04-21 Fu Zhun Precision Industry (Shen Zhen) Co., Ltd. Locking device for heat sink
CN105859716B (zh) * 2016-05-06 2018-03-09 华东师范大学 一种合成喜树碱类化合物中5‑6并环结构的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5626677B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1973-03-26 1981-06-19
JPS5217499A (en) * 1975-07-31 1977-02-09 Nippon Chemiphar Co Ltd Preparation of mappicine
DE2534601C2 (de) * 1975-08-02 1987-01-22 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von Camptothecin und Camptothecin-Derivaten
CA1332413C (en) * 1987-06-25 1994-10-11 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
JP2711728B2 (ja) * 1989-08-29 1998-02-10 株式会社ヤクルト本社 新規キノリン誘導体およびその製造法
US5155225A (en) * 1990-09-28 1992-10-13 Smithkline Beecham Corporation Method for making certain pyrano[3',4':6,7]indolizino-[1,2-B]quinolinones

Also Published As

Publication number Publication date
JPH08501104A (ja) 1996-02-06
WO1994005672A1 (en) 1994-03-17
CN1096297A (zh) 1994-12-14
EP0660835A4 (en) 1995-08-16
EP0660835A1 (en) 1995-07-05
NZ255942A (en) 1996-11-26
TW246674B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1995-05-01
ZA936580B (en) 1994-08-01
KR950702987A (ko) 1995-08-23
AU2859197A (en) 1997-10-23
MX9305517A (es) 1994-05-31
CA2144048A1 (en) 1994-03-17

Similar Documents

Publication Publication Date Title
US5244903A (en) Camptothecin analogs as potent inhibitors of topoisomerase I
FI91872C (fi) Menetelmä terapeuttisesti aktiivisten pyranoindolitsinokinoliinijohdannaisten valmistamiseksi
US5106742A (en) Camptothecin analogs as potent inhibitors of topoisomerase I
ES2254600T3 (es) Nuevos analogos de la camptotecina, procedimientos de preparacion, su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen.
EP0436653A1 (en) Synthesis of camptothecin and analogs thereof
WO1998035940A1 (en) Highly lipophilic camptothecin derivatives
US5364858A (en) Camptothecin analogs as potent inhibitors of topoisomerase I
US5405963A (en) Process for asymmetric total synthesis of camptothecin analogues
NZ520835A (en) Alkylated imidazopyridine derivatives
WO1996021666A1 (en) Camptothecin derivatives and its manufacturing method
EP0555347A1 (en) SUBSTITUTED INDOLIZINO 1,2-b]QUINOLINONES
CA2284747A1 (en) Tetrahydropyrido compounds
JP2003528879A (ja) 三環式イミダゾピリジン
NZ248841A (en) Pyrido[4,3-b]carbazole derivatives (or ellipticines) and medicaments
AU5102393A (en) Process for preparing certain pyrrolo(3,4- b)quinolines, certain 1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-3,14(4H,12H) -diones, and certain
MXPA04011682A (es) Camptotecinas con un anillo lactona modificado.
CA2161318A1 (en) New anthraquinonic derivatives having an antitumor activity, and applications thereof
Albright et al. Synthesis of 1, 4, 5, 6‐tetrahydropyrazolo [3, 4‐d] pyrido [3, 2‐b] azepine
US6169080B1 (en) Highly lipophilic camptothecin derivatives
IL144987A (en) History of homocamptocin and medicinal products containing them
US6500953B1 (en) Preparation of camptothecin and nothapodytine derivatives
Hepburn et al. A concise synthesis of further thiophene analogues of kuanoniamine a
Groundwater et al. Synthesis of pyrido [2, 3-c] acridines
Hermecz et al. A ring transformation of 6, 7-dihydro-4H-pyrido [1, 2-a] pyrimidin-4-ones
MXPA01000767A (en) Preparation of camptothecin and nothapodytine derivatives