AU475168B2 - Anaesthetic pregnanes - Google Patents
Anaesthetic pregnanesInfo
- Publication number
- AU475168B2 AU475168B2 AU55284/73A AU5528473A AU475168B2 AU 475168 B2 AU475168 B2 AU 475168B2 AU 55284/73 A AU55284/73 A AU 55284/73A AU 5528473 A AU5528473 A AU 5528473A AU 475168 B2 AU475168 B2 AU 475168B2
- Authority
- AU
- Australia
- Prior art keywords
- pregnanes
- anaesthetic
- anaesthetic pregnanes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000003444 anaesthetic effect Effects 0.000 title 1
- 150000003128 pregnanes Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2114272A GB1430942A (en) | 1972-05-05 | 1972-05-05 | 21-substituted 3alpha-hydroxy pregnanes |
| GBGB21142/72 | 1972-05-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU5528473A AU5528473A (en) | 1974-11-07 |
| AU475168B2 true AU475168B2 (en) | 1976-08-12 |
Family
ID=10157915
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU55284/73A Expired AU475168B2 (en) | 1972-05-05 | 1973-05-04 | Anaesthetic pregnanes |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS4961150A (enExample) |
| AT (1) | AT355232B (enExample) |
| AU (1) | AU475168B2 (enExample) |
| BE (1) | BE799102A (enExample) |
| CA (1) | CA1013341A (enExample) |
| CH (1) | CH617710A5 (enExample) |
| DE (1) | DE2322532A1 (enExample) |
| ES (1) | ES414411A1 (enExample) |
| FR (1) | FR2183792B1 (enExample) |
| GB (1) | GB1430942A (enExample) |
| IE (1) | IE37596B1 (enExample) |
| IL (1) | IL42196A (enExample) |
| LU (1) | LU67546A1 (enExample) |
| NL (1) | NL7306234A (enExample) |
| SE (1) | SE400771B (enExample) |
| ZA (1) | ZA733035B (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
| US5939545A (en) * | 1994-02-14 | 1999-08-17 | Cocensys, Inc. | Method, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series |
| DK0752860T3 (da) * | 1994-02-14 | 2000-11-13 | Euro Celtique Sa | Androstaner og pregnaner til allosterisk modulering af GABA-receptor |
| GR1003861B (el) * | 2000-12-29 | 2002-04-11 | Νεα νευροστεροειδη που αλληλεπιδρουν με τον υποδοχεα gabaa. | |
| JP4915427B2 (ja) * | 2009-03-30 | 2012-04-11 | ブラザー工業株式会社 | 液体供給ジョイント、これを使用した液体吐出ヘッド及び記録装置 |
| EP3572417B1 (en) | 2011-10-14 | 2025-12-17 | Sage Therapeutics, LLC | 3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof |
| EP2806877B2 (en) | 2012-01-23 | 2025-01-29 | Sage Therapeutics, Inc. | Neuroactive steroid formulations comprising a complex of allopregnanolone and sulfobutyl ether beta-cyclodextrin |
| BR112015003747A2 (pt) | 2012-08-21 | 2017-07-04 | Sage Therapeutics Inc | métodos de tratamento de epilepsia ou estado de mal epiléptico |
| SG10201802389SA (en) | 2013-04-17 | 2018-04-27 | Sage Therapeutics Inc | 19-nor c3,3-disubstituted c21-n-pyrazolyl steroids and methods of use thereof |
| US20160068563A1 (en) | 2013-04-17 | 2016-03-10 | Boyd L. Harrison | 19-nor neuroactive steroids and methods of use thereof |
| US9725481B2 (en) | 2013-04-17 | 2017-08-08 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof |
| ES2998982T3 (en) | 2013-04-17 | 2025-02-24 | Sage Therapeutics Inc | 19-nor neuroactive steroids for inducing sedation |
| PL3021852T3 (pl) | 2013-07-19 | 2021-07-05 | Sage Therapeutics, Inc. | Neuroaktywne steroidy, kompozycje i ich zastosowania |
| HUE052308T2 (hu) | 2013-08-23 | 2021-04-28 | Sage Therapeutics Inc | Neuroaktív szteroidok, készítmények és alkalmazásuk |
| WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| ME03809B (me) | 2014-10-16 | 2021-04-20 | Sage Therapeutics Inc | KOMPOZICIJE I POSTUPCI ZA LEČENJE POREMEĆAJA CNS-a |
| AR102306A1 (es) | 2014-10-16 | 2017-02-15 | Sage Therapeutics Inc | Esteroides neuroactivos útiles en el tratamiento de enfermedades del snc |
| EP3224269B1 (en) | 2014-11-27 | 2020-02-26 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| EP3250210B1 (en) | 2015-01-26 | 2020-12-02 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| US10329320B2 (en) | 2015-02-20 | 2019-06-25 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| CN113616661A (zh) | 2016-03-08 | 2021-11-09 | 萨奇治疗股份有限公司 | 神经活性类固醇、其组合物及用途 |
| EP3481844B1 (en) | 2016-07-11 | 2024-04-17 | Sage Therapeutics, Inc. | C7, c12, and c16 substituted neuroactive steroids and their methods of use |
| ES2965214T3 (es) | 2016-07-11 | 2024-04-11 | Sage Therapeutics Inc | Esteroides neuroactivos sustituidos en C17, C20 y C21 y sus procedimientos de utilización |
| US11643434B2 (en) | 2019-05-31 | 2023-05-09 | Sage Therapeutics, Inc. | Neuroactive steroids and compositions thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1346292A (fr) * | 1962-09-14 | 1963-12-20 | Roussel Uclaf | Nouveau procédé de préparation des 21-amino stéroïdes |
| US3144446A (en) * | 1963-12-20 | 1964-08-11 | Upjohn Co | Mono and bis nu-(3alpha, 17alpha-dihydroxy-11, 20-dioxo-5beta-pregnan-21-yl) quaternary ammonium salts of triethylenediamine |
-
1972
- 1972-05-05 GB GB2114272A patent/GB1430942A/en not_active Expired
-
1973
- 1973-05-04 BE BE130749A patent/BE799102A/xx unknown
- 1973-05-04 AT AT395173A patent/AT355232B/de not_active IP Right Cessation
- 1973-05-04 FR FR7316108A patent/FR2183792B1/fr not_active Expired
- 1973-05-04 JP JP48050183A patent/JPS4961150A/ja active Pending
- 1973-05-04 SE SE7306330A patent/SE400771B/xx unknown
- 1973-05-04 CA CA170,482A patent/CA1013341A/en not_active Expired
- 1973-05-04 ZA ZA733035A patent/ZA733035B/xx unknown
- 1973-05-04 CH CH636073A patent/CH617710A5/de not_active IP Right Cessation
- 1973-05-04 IE IE709/73A patent/IE37596B1/xx unknown
- 1973-05-04 AU AU55284/73A patent/AU475168B2/en not_active Expired
- 1973-05-04 IL IL42196A patent/IL42196A/xx unknown
- 1973-05-04 LU LU67546A patent/LU67546A1/xx unknown
- 1973-05-04 NL NL7306234A patent/NL7306234A/xx not_active Application Discontinuation
- 1973-05-04 ES ES0414411A patent/ES414411A1/es not_active Expired
- 1973-05-04 DE DE2322532A patent/DE2322532A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| GB1430942A (en) | 1976-04-07 |
| IL42196A0 (en) | 1973-07-30 |
| LU67546A1 (enExample) | 1973-07-13 |
| FR2183792A1 (enExample) | 1973-12-21 |
| JPS4961150A (enExample) | 1974-06-13 |
| BE799102A (fr) | 1973-11-05 |
| ES414411A1 (es) | 1976-02-01 |
| CH617710A5 (en) | 1980-06-13 |
| CA1013341A (en) | 1977-07-05 |
| AT355232B (de) | 1980-02-25 |
| DE2322532A1 (de) | 1973-11-22 |
| IE37596L (en) | 1973-11-05 |
| NL7306234A (enExample) | 1973-11-07 |
| ATA395173A (de) | 1979-07-15 |
| SE400771B (sv) | 1978-04-10 |
| ZA733035B (en) | 1974-04-24 |
| IE37596B1 (en) | 1977-08-31 |
| FR2183792B1 (enExample) | 1977-07-15 |
| AU5528473A (en) | 1974-11-07 |
| IL42196A (en) | 1978-10-31 |
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