AU469581B2 - Nitric acid esters of 21-alcohols belonging tothe pregnane series anda process forthe preparation thereof - Google Patents

Nitric acid esters of 21-alcohols belonging tothe pregnane series anda process forthe preparation thereof

Info

Publication number
AU469581B2
AU469581B2 AU41722/72A AU4172272A AU469581B2 AU 469581 B2 AU469581 B2 AU 469581B2 AU 41722/72 A AU41722/72 A AU 41722/72A AU 4172272 A AU4172272 A AU 4172272A AU 469581 B2 AU469581 B2 AU 469581B2
Authority
AU
Australia
Prior art keywords
acid esters
nitric acid
process forthe
pregnane series
forthe preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU41722/72A
Other languages
English (en)
Other versions
AU4172272A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of AU4172272A publication Critical patent/AU4172272A/en
Application granted granted Critical
Publication of AU469581B2 publication Critical patent/AU469581B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU41722/72A 1971-05-07 1972-05-01 Nitric acid esters of 21-alcohols belonging tothe pregnane series anda process forthe preparation thereof Expired AU469581B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HURI429A HU164115B (enExample) 1971-05-07 1971-05-07
HUHURI-429 1971-05-07

Publications (2)

Publication Number Publication Date
AU4172272A AU4172272A (en) 1973-11-08
AU469581B2 true AU469581B2 (en) 1976-02-19

Family

ID=11000864

Family Applications (1)

Application Number Title Priority Date Filing Date
AU41722/72A Expired AU469581B2 (en) 1971-05-07 1972-05-01 Nitric acid esters of 21-alcohols belonging tothe pregnane series anda process forthe preparation thereof

Country Status (15)

Country Link
JP (1) JPS5330707B1 (enExample)
AT (1) AT316767B (enExample)
AU (1) AU469581B2 (enExample)
CA (1) CA975755A (enExample)
CS (2) CS171259B2 (enExample)
DD (1) DD98668A5 (enExample)
DE (1) DE2222491C3 (enExample)
ES (1) ES402230A1 (enExample)
FR (1) FR2143664A1 (enExample)
HU (1) HU164115B (enExample)
NL (1) NL7206134A (enExample)
PL (1) PL75494B1 (enExample)
SE (2) SE385590B (enExample)
SU (1) SU493963A3 (enExample)
YU (1) YU34701B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792758A (en) * 1995-12-08 1998-08-11 G. D. Searle & Co. Steroid nitrite ester derivatives useful as anti-inflammatory drugs
US5707984A (en) * 1995-12-08 1998-01-13 G. D. Searle & Co. Steroid nitrite/nitrate ester derivatives useful as anti-inflammatory drugs
US5824669A (en) * 1996-03-22 1998-10-20 Nitromed, Inc. Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
US5837698A (en) * 1996-05-02 1998-11-17 G. D. Searle & Co. Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs
US5985862A (en) * 1996-05-02 1999-11-16 G.D. Searle & Co. Pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs
IT1285770B1 (it) 1996-10-04 1998-06-18 Nicox Sa Composti corticoidei
ITMI20020148A1 (it) 2002-01-29 2003-07-29 Nicox Sa Nuovi corticosteroidi
CN101652380A (zh) 2007-02-05 2010-02-17 尼科克斯公司 释放一氧化氮的类固醇
PT2805720T (pt) 2008-05-28 2019-09-23 Reveragen Biopharma Inc Moduladores esteroides não hormonais de nf-kb para tratamento de uma doença
EP2556083A4 (en) 2010-04-05 2013-12-04 Validus Biopharma Inc NONHORMONAL STEROID MODULATORS OF NF-KAPPA-B FOR DISEASE TREATMENT
US8716268B2 (en) 2010-06-07 2014-05-06 Chao Liu Nitrate esters of corticoid compounds useful as diuretics
US10799514B2 (en) 2015-06-29 2020-10-13 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-kappa beta for treatment of disease
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Also Published As

Publication number Publication date
AT316767B (de) 1974-07-25
PL75494B1 (enExample) 1974-12-31
CS171258B2 (enExample) 1976-10-29
YU34701B (en) 1979-12-31
FR2143664A1 (en) 1973-02-09
SE385590B (sv) 1976-07-12
SU493963A3 (ru) 1975-11-28
DE2222491A1 (de) 1972-11-16
DE2222491B2 (de) 1977-09-29
DE2222491C3 (de) 1978-05-03
JPS5330707B1 (enExample) 1978-08-29
CA975755A (en) 1975-10-07
ES402230A1 (es) 1975-03-16
YU111772A (en) 1979-07-10
FR2143664B1 (enExample) 1976-07-02
NL7206134A (enExample) 1972-11-09
AU4172272A (en) 1973-11-08
DD98668A5 (enExample) 1973-07-05
CS171259B2 (enExample) 1976-10-29
SE7503290L (enExample) 1975-03-21
HU164115B (enExample) 1973-12-28

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