CA975755A - Nitric acid esters of 21-alcohols belonging to the pregnane series as well as a process for the preparation thereof - Google Patents
Nitric acid esters of 21-alcohols belonging to the pregnane series as well as a process for the preparation thereofInfo
- Publication number
- CA975755A CA975755A CA141,366A CA141366A CA975755A CA 975755 A CA975755 A CA 975755A CA 141366 A CA141366 A CA 141366A CA 975755 A CA975755 A CA 975755A
- Authority
- CA
- Canada
- Prior art keywords
- preparation
- well
- acid esters
- nitric acid
- pregnane series
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HURI429A HU164115B (en) | 1971-05-07 | 1971-05-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA975755A true CA975755A (en) | 1975-10-07 |
Family
ID=11000864
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA141,366A Expired CA975755A (en) | 1971-05-07 | 1972-05-05 | Nitric acid esters of 21-alcohols belonging to the pregnane series as well as a process for the preparation thereof |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS5330707B1 (en) |
AT (1) | AT316767B (en) |
AU (1) | AU469581B2 (en) |
CA (1) | CA975755A (en) |
CS (2) | CS171258B2 (en) |
DD (1) | DD98668A5 (en) |
DE (1) | DE2222491C3 (en) |
ES (1) | ES402230A1 (en) |
FR (1) | FR2143664A1 (en) |
HU (1) | HU164115B (en) |
NL (1) | NL7206134A (en) |
PL (1) | PL75494B1 (en) |
SE (2) | SE385590B (en) |
SU (1) | SU493963A3 (en) |
YU (1) | YU34701B (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5707984A (en) * | 1995-12-08 | 1998-01-13 | G. D. Searle & Co. | Steroid nitrite/nitrate ester derivatives useful as anti-inflammatory drugs |
US5792758A (en) * | 1995-12-08 | 1998-08-11 | G. D. Searle & Co. | Steroid nitrite ester derivatives useful as anti-inflammatory drugs |
US5824669A (en) * | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
US5837698A (en) * | 1996-05-02 | 1998-11-17 | G. D. Searle & Co. | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs |
US8207151B2 (en) | 2008-05-28 | 2012-06-26 | Validus Biopharma Inc. | Non-hormonal steroid modulators of NF-κB for treatment of disease |
US9198921B2 (en) | 2010-04-05 | 2015-12-01 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-κB for treatment of disease |
US10799514B2 (en) | 2015-06-29 | 2020-10-13 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kappa beta for treatment of disease |
US11382922B2 (en) | 2019-03-07 | 2022-07-12 | Reveragen Biopharma, Inc. | Aqueous oral pharmaceutical suspension compositions |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5985862A (en) * | 1996-05-02 | 1999-11-16 | G.D. Searle & Co. | Pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs |
IT1285770B1 (en) | 1996-10-04 | 1998-06-18 | Nicox Sa | CORTICOID COMPOUNDS |
ITMI20020148A1 (en) | 2002-01-29 | 2003-07-29 | Nicox Sa | NEW CORTICOSTEROIDS |
WO2008095806A1 (en) | 2007-02-05 | 2008-08-14 | Nicox S.A. | Nitric oxide releasing steroids |
US8716268B2 (en) | 2010-06-07 | 2014-05-06 | Chao Liu | Nitrate esters of corticoid compounds useful as diuretics |
-
1971
- 1971-05-07 HU HURI429A patent/HU164115B/hu unknown
-
1972
- 1972-04-20 AT AT345872A patent/AT316767B/en not_active IP Right Cessation
- 1972-04-22 ES ES402230A patent/ES402230A1/en not_active Expired
- 1972-04-26 YU YU1117/72A patent/YU34701B/en unknown
- 1972-04-28 DD DD162651A patent/DD98668A5/xx unknown
- 1972-05-01 AU AU41722/72A patent/AU469581B2/en not_active Expired
- 1972-05-04 JP JP4376772A patent/JPS5330707B1/ja active Pending
- 1972-05-04 FR FR7215938A patent/FR2143664A1/en active Granted
- 1972-05-05 CA CA141,366A patent/CA975755A/en not_active Expired
- 1972-05-05 PL PL15518272A patent/PL75494B1/pl unknown
- 1972-05-05 NL NL7206134A patent/NL7206134A/xx not_active Application Discontinuation
- 1972-05-05 CS CS3050A patent/CS171258B2/cs unknown
- 1972-05-05 CS CS2266*[A patent/CS171259B2/cs unknown
- 1972-05-05 SE SE7205915A patent/SE385590B/en unknown
- 1972-05-05 SU SU1783400A patent/SU493963A3/en active
- 1972-05-08 DE DE2222491A patent/DE2222491C3/en not_active Expired
-
1975
- 1975-03-21 SE SE7503290A patent/SE7503290L/xx unknown
Cited By (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5707984A (en) * | 1995-12-08 | 1998-01-13 | G. D. Searle & Co. | Steroid nitrite/nitrate ester derivatives useful as anti-inflammatory drugs |
US5792758A (en) * | 1995-12-08 | 1998-08-11 | G. D. Searle & Co. | Steroid nitrite ester derivatives useful as anti-inflammatory drugs |
US5824669A (en) * | 1996-03-22 | 1998-10-20 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
US6197762B1 (en) | 1996-03-22 | 2001-03-06 | Nitromed, Inc. | Nitrosated and nitrosylated steroids compositions, and methods for treating respiratory disorders |
USRE37116E1 (en) * | 1996-03-22 | 2001-03-27 | Nitromed, Inc. | Nitrosated and nitrosylated compounds, and compositions and their use for treating respiratory disorders |
US6579863B1 (en) | 1996-03-22 | 2003-06-17 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
US7160920B2 (en) | 1996-03-22 | 2007-01-09 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
US7345037B2 (en) | 1996-03-22 | 2008-03-18 | Nitromed, Inc. | Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders |
US5837698A (en) * | 1996-05-02 | 1998-11-17 | G. D. Searle & Co. | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs |
US8334279B2 (en) | 2008-05-28 | 2012-12-18 | Validus Genetics | Non-hormonal steroid modulators of NF-κB for treatment of disease |
US10206933B2 (en) | 2008-05-28 | 2019-02-19 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kB for treatment of disease |
US8673887B2 (en) | 2008-05-28 | 2014-03-18 | Reveragen Biopharma, Inc | Non-hormonal steroid modulators of NF-kB for treatment of disease |
US11833159B2 (en) | 2008-05-28 | 2023-12-05 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kB for treatment of disease |
US9434758B2 (en) | 2008-05-28 | 2016-09-06 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-κB for treatment of disease |
US9649320B2 (en) | 2008-05-28 | 2017-05-16 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-κB for treatment of disease |
US10857161B2 (en) | 2008-05-28 | 2020-12-08 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kB for treatment of disease |
US8207151B2 (en) | 2008-05-28 | 2012-06-26 | Validus Biopharma Inc. | Non-hormonal steroid modulators of NF-κB for treatment of disease |
US10000525B2 (en) | 2010-04-05 | 2018-06-19 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-κB for treatment of disease |
US9198921B2 (en) | 2010-04-05 | 2015-12-01 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-κB for treatment of disease |
US10799514B2 (en) | 2015-06-29 | 2020-10-13 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kappa beta for treatment of disease |
US11690853B2 (en) | 2015-06-29 | 2023-07-04 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-κβ for treatment of disease |
US11382922B2 (en) | 2019-03-07 | 2022-07-12 | Reveragen Biopharma, Inc. | Aqueous oral pharmaceutical suspension compositions |
US11471471B2 (en) | 2019-03-07 | 2022-10-18 | Reveragen Biopharma, Inc. | Aqueous oral pharmaceutical suspension compositions |
Also Published As
Publication number | Publication date |
---|---|
SU493963A3 (en) | 1975-11-28 |
AU469581B2 (en) | 1976-02-19 |
DE2222491C3 (en) | 1978-05-03 |
DE2222491A1 (en) | 1972-11-16 |
YU111772A (en) | 1979-07-10 |
CS171258B2 (en) | 1976-10-29 |
PL75494B1 (en) | 1974-12-31 |
AT316767B (en) | 1974-07-25 |
HU164115B (en) | 1973-12-28 |
FR2143664B1 (en) | 1976-07-02 |
AU4172272A (en) | 1973-11-08 |
NL7206134A (en) | 1972-11-09 |
SE7503290L (en) | 1975-03-21 |
DE2222491B2 (en) | 1977-09-29 |
YU34701B (en) | 1979-12-31 |
JPS5330707B1 (en) | 1978-08-29 |
SE385590B (en) | 1976-07-12 |
FR2143664A1 (en) | 1973-02-09 |
DD98668A5 (en) | 1973-07-05 |
CS171259B2 (en) | 1976-10-29 |
ES402230A1 (en) | 1975-03-16 |
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