AU467944B2 - 4-aminoquinoline derivatives - Google Patents

4-aminoquinoline derivatives

Info

Publication number
AU467944B2
AU467944B2 AU52421/73A AU5242173A AU467944B2 AU 467944 B2 AU467944 B2 AU 467944B2 AU 52421/73 A AU52421/73 A AU 52421/73A AU 5242173 A AU5242173 A AU 5242173A AU 467944 B2 AU467944 B2 AU 467944B2
Authority
AU
Australia
Prior art keywords
group
compound
chloro
formula
addition salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU52421/73A
Other languages
English (en)
Other versions
AU5242173A (en
Inventor
Leiieup Archibald John Terence Arnott Boyle John Christopher Saunders John
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
John Wyeth and Brother Ltd
Original Assignee
John Wyeth and Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by John Wyeth and Brother Ltd filed Critical John Wyeth and Brother Ltd
Publication of AU5242173A publication Critical patent/AU5242173A/en
Application granted granted Critical
Publication of AU467944B2 publication Critical patent/AU467944B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU52421/73A 1972-03-10 1973-02-21 4-aminoquinoline derivatives Expired AU467944B2 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GBGB11251/72 1972-03-10
GB1125172 1972-03-10
GB3063572 1972-06-30
GBGB30635/72 1972-06-30
GBGB48593/72 1972-10-21
GB4859372 1972-10-21
GB553173A GB1416872A (en) 1972-03-10 1973-02-05 4-aminoquinoline derivatives
GBGB5531/73 1973-02-05

Publications (2)

Publication Number Publication Date
AU5242173A AU5242173A (en) 1974-10-17
AU467944B2 true AU467944B2 (en) 1975-12-18

Family

ID=27447454

Family Applications (1)

Application Number Title Priority Date Filing Date
AU52421/73A Expired AU467944B2 (en) 1972-03-10 1973-02-21 4-aminoquinoline derivatives

Country Status (10)

Country Link
JP (1) JPS604187B2 (enFirst)
AU (1) AU467944B2 (enFirst)
BE (1) BE855713Q (enFirst)
CH (2) CH577476A5 (enFirst)
DE (1) DE2311570C2 (enFirst)
FR (1) FR2181807B1 (enFirst)
GB (1) GB1416872A (enFirst)
HK (1) HK10279A (enFirst)
KE (1) KE2916A (enFirst)
MY (1) MY7900137A (enFirst)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA743270B (en) * 1973-06-15 1975-05-28 Upjohn Co Anti-hypertensive compounds
GB1474296A (en) * 1975-01-23 1977-05-18 Wyeth John & Brother Ltd 4-aminoquinoline derivatives
JPS5717907Y2 (enFirst) * 1977-09-05 1982-04-14
GB1573186A (en) * 1977-09-14 1980-08-20 Wyeth John & Brother Ltd 4-aminoquinoline derivatives
JPS6055170A (ja) * 1983-09-05 1985-03-30 株式会社多川工業 鉄骨切断装置
PH22302A (en) * 1985-02-11 1988-07-22 Fujisawa Pharmaceutical Co Piperidine compounds
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
CN1052224C (zh) * 1993-04-07 2000-05-10 大塚制药株式会社 哌啶衍生物、含有它的外周血管舒张剂及其应用
US5567718A (en) * 1994-08-11 1996-10-22 Hoechst Marion Roussel Inc. 2,3-dihydro-1h-isoindole derivatives and their use as serotonin reuptake inhibitors
AUPP818099A0 (en) * 1999-01-14 1999-02-11 Fujisawa Pharmaceutical Co., Ltd. New n-containing heterocyclic compounds
SE0000540D0 (sv) 2000-02-18 2000-02-18 Astrazeneca Ab New compounds
MY142362A (en) 2004-01-29 2010-11-30 Otsuka Pharma Co Ltd Pharmaceutical composition for promoting angiogenesis
WO2007108936A2 (en) 2006-03-15 2007-09-27 Wyeth N-substituted-azacyclylamines as histamine-3 antagonists
CA2649913A1 (en) 2006-05-19 2007-11-29 Wyeth N-benzoyl- and n-benzylpyrrolidin-3-ylamines as histamine-3 antagonists
JP5164842B2 (ja) * 2006-07-28 2013-03-21 株式会社カネカ 光学活性３−アミノ含窒素化合物の製造法
PE20081152A1 (es) 2006-10-06 2008-08-10 Wyeth Corp Azaciclilaminas n-sustituidas como antagonistas de histamina-3
US7946311B2 (en) 2007-02-01 2011-05-24 Hobart Brorthers Company Robust preconditioned air hose
CA2693138A1 (en) 2007-07-16 2009-01-22 Wyeth Llc Aminoalkylazole derivatives as histamine-3 antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA731646A (en) * 1962-05-08 1966-04-05 Roussel-Uclaf 4-(2'(.beta.-MORPHOLYLETHOXYCARBONYL) PHENYLAMINE) 7-CHLORO QUINOLEINE ET SES SELS, AINSI QUE LEUR PROCEDE DE PREPARATION
BE754587A (fr) * 1969-08-08 1971-02-08 Upjohn Co Nouveaux p-(trihalomethylquinolylamino) benzamides et leur procede de preparation
BE754586A (fr) * 1969-08-08 1971-02-08 Upjohn Co Preparations pharmaceutiques a base de p-(4-quinolylamino) benzamide etleur utilisation

Also Published As

Publication number Publication date
JPS49273A (enFirst) 1974-01-05
HK10279A (en) 1979-03-09
MY7900137A (en) 1979-12-31
GB1416872A (en) 1975-12-10
CH577476A5 (enFirst) 1976-07-15
KE2916A (en) 1979-03-30
FR2181807A1 (enFirst) 1973-12-07
DE2311570A1 (de) 1973-09-13
BE855713Q (fr) 1977-10-03
DE2311570C2 (de) 1986-03-13
AU5242173A (en) 1974-10-17
JPS604187B2 (ja) 1985-02-01
CH576964A5 (enFirst) 1976-06-30
FR2181807B1 (enFirst) 1976-10-22

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