AU4504793A - Method for preparing membrane proteins and preserving their oligomeric structures under denaturing conditions, and uses of said proteins in diagnostics and vaccination - Google Patents

Method for preparing membrane proteins and preserving their oligomeric structures under denaturing conditions, and uses of said proteins in diagnostics and vaccination

Info

Publication number
AU4504793A
AU4504793A AU45047/93A AU4504793A AU4504793A AU 4504793 A AU4504793 A AU 4504793A AU 45047/93 A AU45047/93 A AU 45047/93A AU 4504793 A AU4504793 A AU 4504793A AU 4504793 A AU4504793 A AU 4504793A
Authority
AU
Australia
Prior art keywords
proteins
vaccination
diagnostics
preserving
denaturing conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU45047/93A
Other languages
English (en)
Inventor
Jean-Jacques Madjar
Herve Poly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Pasteur Merieux Serum et Vaccines SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Merieux Serum et Vaccines SA filed Critical Pasteur Merieux Serum et Vaccines SA
Publication of AU4504793A publication Critical patent/AU4504793A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU45047/93A 1992-06-30 1993-06-29 Method for preparing membrane proteins and preserving their oligomeric structures under denaturing conditions, and uses of said proteins in diagnostics and vaccination Abandoned AU4504793A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9208051 1992-06-30
FR9208051A FR2692898B1 (fr) 1992-06-30 1992-06-30 Procédé d'obtention de protéines membranaires, et utilisation de ces protéines dans un but de diagnostic ou de vaccination.
PCT/FR1993/000654 WO1994000557A1 (fr) 1992-06-30 1993-06-29 Procede d'obtention de proteines membranaires, permettant le maintien des structures oligomeriques de ces proteines en conditions denaturantes, et utilisation de ces proteines dans un but de diagnostic ou de vaccination

Publications (1)

Publication Number Publication Date
AU4504793A true AU4504793A (en) 1994-01-24

Family

ID=9431365

Family Applications (1)

Application Number Title Priority Date Filing Date
AU45047/93A Abandoned AU4504793A (en) 1992-06-30 1993-06-29 Method for preparing membrane proteins and preserving their oligomeric structures under denaturing conditions, and uses of said proteins in diagnostics and vaccination

Country Status (3)

Country Link
AU (1) AU4504793A (fr)
FR (1) FR2692898B1 (fr)
WO (1) WO1994000557A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914390A (en) * 1997-05-12 1999-06-22 Celtrix Pharmaceuticals, Inc. Methods for increasing yields of recombinant proteins
DE19801090A1 (de) * 1998-01-14 1999-07-15 Gerhard Haase Lysis-Filtrations-Assay LYFA
FR2781676B1 (fr) * 1998-07-31 2004-04-02 Pasteur Merieux Serums Vacc Trimere du produit d'expression du gene env de hiv
DE19939246A1 (de) 1999-08-19 2001-02-22 Phasys Gmbh M Rückfaltung von Membranproteinen
WO2024056508A1 (fr) 2022-09-15 2024-03-21 Cube Biotech Gmbh Procédé de diagnostic in vitro pour détecter la présence d'une cible à l'aide de protéines membranaires stabilisées

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752473A (en) * 1984-10-12 1988-06-21 The Regents Of The University Of California Expression of glycosylated human influenza hemagglutinin proteins
EP0295859B1 (fr) * 1987-06-15 1994-11-17 Southern Cross Biotech Pty.Ltd. Préparation de protéines dans les formes actives
JPS6447435A (en) * 1987-08-18 1989-02-21 Oriental Yeast Co Ltd Dispersant for biologically active peptide
ES2059355T3 (es) * 1987-12-23 1994-11-16 Immuno Ag Proteinas anfipaticas celulares en forma de agregados y procedimiento para la produccion y la purificacion de estas proteinas.
DE3809796A1 (de) * 1988-03-23 1989-10-05 Wolfgang Prof Dr Med Bredt Verfahren zum reinigen eines 168 kd-proteins von mycoplasma pneumoniae
AU640348B2 (en) * 1988-08-31 1993-08-26 Smithkline Beecham Corporation Vaccinal Polypeptides
DE69026569T2 (de) * 1989-05-12 1996-09-05 Institut Pasteur, Paris Antigene eines transmembranen hüllenglycoproteins eines menschlichen retrovirus des typs hiv-2 und immunologisch verwandte antigene
AU641210B2 (en) * 1989-10-24 1993-09-16 Berlex Laboratories, Inc. Gastrin releasing peptide receptor
JPH03271233A (ja) * 1990-03-19 1991-12-03 Inst Pasteur ウイルスエンベロープ糖タンパク質及びその糖タンパク質の中和エピトープに対応するペプチドの間の相乗作用による、ウイルス性感染に対する防御の誘発
DD300690A5 (de) * 1990-03-23 1992-07-02 Univ Berlin Humboldt Verfahren zur Herstellung eines Derivates des Transmembranproteins Gp41 deshumanen Immundeffizienzvirus 1 (Penv 474-647) in E. Coli

Also Published As

Publication number Publication date
FR2692898B1 (fr) 1995-06-02
FR2692898A1 (fr) 1993-12-31
WO1994000557A1 (fr) 1994-01-06

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