AU4388993A - Treatment of cellular hyperproliferation by inhibition of interleukin-1 - Google Patents
Treatment of cellular hyperproliferation by inhibition of interleukin-1Info
- Publication number
- AU4388993A AU4388993A AU43889/93A AU4388993A AU4388993A AU 4388993 A AU4388993 A AU 4388993A AU 43889/93 A AU43889/93 A AU 43889/93A AU 4388993 A AU4388993 A AU 4388993A AU 4388993 A AU4388993 A AU 4388993A
- Authority
- AU
- Australia
- Prior art keywords
- oligomer
- interleukin
- cytokine
- cells
- target gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/312—Phosphonates
- C12N2310/3125—Methylphosphonates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US88773492A | 1992-05-22 | 1992-05-22 | |
US887734 | 1992-05-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4388993A true AU4388993A (en) | 1993-12-30 |
Family
ID=25391751
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU43889/93A Abandoned AU4388993A (en) | 1992-05-22 | 1993-05-21 | Treatment of cellular hyperproliferation by inhibition of interleukin-1 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0644765A4 (es) |
JP (1) | JPH07508977A (es) |
KR (1) | KR950701528A (es) |
AU (1) | AU4388993A (es) |
CA (1) | CA2136349A1 (es) |
IL (1) | IL105741A0 (es) |
MX (1) | MX9302951A (es) |
NZ (1) | NZ253509A (es) |
WO (1) | WO1993024134A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6858409B1 (en) | 1988-05-27 | 2005-02-22 | Amgen Inc. | Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors |
US5075222A (en) | 1988-05-27 | 1991-12-24 | Synergen, Inc. | Interleukin-1 inhibitors |
US6159460A (en) * | 1988-05-27 | 2000-12-12 | Amgen Inc. | Method for treating interleukin-1 mediated diseases |
GB9405021D0 (en) * | 1994-03-15 | 1994-04-27 | Unilever Plc | Skin treatment composition |
ATE428785T1 (de) | 1996-03-01 | 2009-05-15 | Euroscreen Sa | Aktive und inactive cc-chemokinrezeptoren und nukleinsäuremoleküle, die für diesen rezeptor kodieren |
US6294170B1 (en) | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
IL133913A0 (en) * | 1997-07-10 | 2001-04-30 | Therakos Inc | Treatment of inflammatory disorders of the bowel and urinary bladder |
WO2004100987A2 (en) * | 2003-05-06 | 2004-11-25 | Regeneron Pharmaceuticals, Inc. | Methods of using il-1 antagonists to treat neointimal hyperplasia |
US7960355B2 (en) | 2003-05-23 | 2011-06-14 | Isis Pharmaceuticals, Inc. | Compositions and methods for the modulation of the expression of B7 protein |
US7897582B2 (en) | 2003-05-23 | 2011-03-01 | Isis Pharmaceuticals, Inc. | Oligonucleotide compositions and methods for the modulation of the expression of B7 protein |
WO2006084145A2 (en) * | 2005-02-02 | 2006-08-10 | Regeneron Pharmaceuticals, Inc. | Methods of using il-1 antagonists to reduce c-reactive protein |
GB0607189D0 (en) * | 2006-04-10 | 2006-05-17 | Polybiomed Ltd | interleukin IL 1ra composition |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0353290A4 (en) * | 1988-01-21 | 1990-09-05 | Chemex Pharmaceuticals, Inc. | Selective inhibition of gene expression by photoactivatable oligonucleotides |
EP0527790A4 (en) * | 1990-04-09 | 1993-09-15 | The American National Red Cross | Rejuvenation compositions and methods for their use |
US5135917A (en) * | 1990-07-12 | 1992-08-04 | Nova Pharmaceutical Corporation | Interleukin receptor expression inhibiting antisense oligonucleotides |
IL101978A0 (en) * | 1991-05-31 | 1992-12-30 | Genta Inc | Neutral oligomers capable of being delivered transdermally and across mucous membranes |
HU220098B (hu) * | 1991-08-30 | 2001-10-28 | Vertex Pharmaceuticals Incorporated | Interleukin-1 béta proteáz enzim, és interleukin-1 béta proteáz inhibitorok |
-
1993
- 1993-05-19 IL IL105741A patent/IL105741A0/xx unknown
- 1993-05-20 MX MX9302951A patent/MX9302951A/es unknown
- 1993-05-21 EP EP93914110A patent/EP0644765A4/en not_active Withdrawn
- 1993-05-21 KR KR1019940704197A patent/KR950701528A/ko not_active Application Discontinuation
- 1993-05-21 AU AU43889/93A patent/AU4388993A/en not_active Abandoned
- 1993-05-21 WO PCT/US1993/004917 patent/WO1993024134A1/en not_active Application Discontinuation
- 1993-05-21 CA CA002136349A patent/CA2136349A1/en not_active Abandoned
- 1993-05-21 NZ NZ253509A patent/NZ253509A/en not_active IP Right Cessation
- 1993-05-21 JP JP6500694A patent/JPH07508977A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0644765A4 (en) | 1997-02-26 |
MX9302951A (es) | 1994-07-29 |
KR950701528A (ko) | 1995-04-28 |
EP0644765A1 (en) | 1995-03-29 |
WO1993024134A1 (en) | 1993-12-09 |
NZ253509A (en) | 1999-09-29 |
JPH07508977A (ja) | 1995-10-05 |
IL105741A0 (en) | 1993-09-22 |
CA2136349A1 (en) | 1993-12-09 |
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