AU4250596A - Low molecular weight bicyclic thrombin inhibitors - Google Patents
Low molecular weight bicyclic thrombin inhibitorsInfo
- Publication number
- AU4250596A AU4250596A AU42505/96A AU4250596A AU4250596A AU 4250596 A AU4250596 A AU 4250596A AU 42505/96 A AU42505/96 A AU 42505/96A AU 4250596 A AU4250596 A AU 4250596A AU 4250596 A AU4250596 A AU 4250596A
- Authority
- AU
- Australia
- Prior art keywords
- molecular weight
- low molecular
- thrombin inhibitors
- bicyclic
- weight bicyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9426038 | 1994-12-22 | ||
| GBGB9426038.7A GB9426038D0 (en) | 1994-12-22 | 1994-12-22 | Low molecular weight bicyclic thrombin inhibitors |
| GB9503136 | 1995-02-17 | ||
| GBGB9503136.5A GB9503136D0 (en) | 1994-12-22 | 1995-02-17 | Low molecular weight bicyclic thrombin inhibitors |
| GBGB9510267.9A GB9510267D0 (en) | 1995-05-22 | 1995-05-22 | Low molecular weight thiobicyclic thrombin inhibitors |
| GB9510267 | 1995-05-22 | ||
| GBGB9510265.3A GB9510265D0 (en) | 1995-05-22 | 1995-05-22 | Low molecular weight diaminobicyclic thrombin inhibitors |
| GBGB9510266.1A GB9510266D0 (en) | 1995-05-22 | 1995-05-22 | Low molecular weight bicyclic thrombin inhibitors |
| GB9510265 | 1995-05-22 | ||
| GB9510266 | 1995-05-22 | ||
| PCT/CA1995/000708 WO1996019483A1 (en) | 1994-12-22 | 1995-12-21 | Low molecular weight bicyclic thrombin inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU4250596A true AU4250596A (en) | 1996-07-10 |
Family
ID=27517273
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU42505/96A Abandoned AU4250596A (en) | 1994-12-22 | 1995-12-21 | Low molecular weight bicyclic thrombin inhibitors |
| AU40628/95A Ceased AU715378B2 (en) | 1994-12-22 | 1995-12-22 | Low molecular weight bicyclic thrombin inhibitors |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU40628/95A Ceased AU715378B2 (en) | 1994-12-22 | 1995-12-22 | Low molecular weight bicyclic thrombin inhibitors |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0802916A1 (en) |
| JP (1) | JPH11508535A (en) |
| CN (1) | CN1175259A (en) |
| AP (1) | AP9701004A0 (en) |
| AU (2) | AU4250596A (en) |
| BG (1) | BG101647A (en) |
| CA (1) | CA2208772A1 (en) |
| CZ (1) | CZ189997A3 (en) |
| EE (1) | EE9700113A (en) |
| FI (1) | FI972466A (en) |
| HU (1) | HUT77651A (en) |
| IL (1) | IL116503A0 (en) |
| IS (1) | IS4504A (en) |
| LV (1) | LV12019B (en) |
| MD (1) | MD970253A (en) |
| MX (1) | MX9704718A (en) |
| NO (1) | NO972892L (en) |
| NZ (1) | NZ297360A (en) |
| OA (1) | OA10493A (en) |
| PL (1) | PL320965A1 (en) |
| SK (1) | SK83897A3 (en) |
| WO (1) | WO1996019483A1 (en) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6699869B1 (en) | 1995-03-24 | 2004-03-02 | Myriad Genetics Inc. | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins |
| US6020331A (en) * | 1995-03-24 | 2000-02-01 | Molecumetics, Ltd. | β-sheet mimetics and use thereof as protease inhibitors |
| US6245764B1 (en) | 1995-03-24 | 2001-06-12 | Molecumetics Ltd. | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins |
| IT1277405B1 (en) * | 1995-08-01 | 1997-11-10 | Menarini Farma Ind | BICYCLIC LACTAM DERIVATIVES AS THROMBIN INHIBITORS |
| IL119466A (en) | 1995-11-03 | 2001-08-26 | Akzo Nobel Nv | Thrombin inhibitors, their preparation and pharmaceutical compositions containing them |
| US6034067A (en) * | 1996-02-13 | 2000-03-07 | Akzo Nobel, N.V. | Serine protease inhibitors |
| IL120310A (en) * | 1996-03-01 | 2002-02-10 | Akzo Nobel Nv | Serine protease inhibitors and pharmaceutical compositions containing them |
| TW523513B (en) * | 1996-03-01 | 2003-03-11 | Akzo Nobel Nv | Serine protease inhibitors |
| US6124291A (en) * | 1996-06-18 | 2000-09-26 | Warner-Lambert Company | Pyrrolo[1,2-a]pyrazine-1,4-dione serine protease inhibitors |
| EP1661566A3 (en) * | 1996-08-05 | 2008-04-16 | Myriad Genetics, Inc. | Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors |
| CA2262900A1 (en) * | 1996-08-05 | 1998-02-12 | Molecumetics Ltd. | Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors |
| US6117896A (en) | 1997-02-10 | 2000-09-12 | Molecumetics Ltd. | Methods for regulating transcription factors |
| AU4172397A (en) * | 1996-09-06 | 1998-03-26 | Biochem Pharma Inc. | Lactam inhibitors of thrombin |
| US6369080B2 (en) | 1996-10-11 | 2002-04-09 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6194435B1 (en) | 1996-10-11 | 2001-02-27 | Cor Therapeutics, Inc. | Lactams as selective factor Xa inhibitors |
| US6262047B1 (en) | 1996-10-11 | 2001-07-17 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6063794A (en) | 1996-10-11 | 2000-05-16 | Cor Therapeutics Inc. | Selective factor Xa inhibitors |
| WO1998028326A1 (en) * | 1996-12-23 | 1998-07-02 | Biochem Pharma Inc. | Bicyclic thrombin inhibitors |
| EP0975659A1 (en) * | 1997-04-14 | 2000-02-02 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
| AU6896298A (en) | 1997-04-14 | 1998-11-11 | Cor Therapeutics, Inc. | Selective factor xa inhibitors |
| NZ500352A (en) | 1997-04-14 | 2001-10-26 | Cor Therapeutics Inc | Cyclic diaza selective factor Xa inhibitors |
| US6333321B1 (en) | 1997-08-11 | 2001-12-25 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6228854B1 (en) | 1997-08-11 | 2001-05-08 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
| US6218382B1 (en) | 1997-08-11 | 2001-04-17 | Cor Therapeutics, Inc | Selective factor Xa inhibitors |
| AU740447B2 (en) * | 1997-09-23 | 2001-11-01 | Merck & Co., Inc. | Thrombin inhibitors |
| ES2192764T3 (en) * | 1998-02-12 | 2003-10-16 | Molecumetics Ltd | MIMETICS OF LAMINA BETA AND METHODS RELATED TO THE USE OF THE SAME. |
| US6323219B1 (en) | 1998-04-02 | 2001-11-27 | Ortho-Mcneil Pharmaceutical, Inc. | Methods for treating immunomediated inflammatory disorders |
| US8093293B2 (en) | 1998-07-06 | 2012-01-10 | Johnson & Johnson Consumer Companies, Inc. | Methods for treating skin conditions |
| US8106094B2 (en) | 1998-07-06 | 2012-01-31 | Johnson & Johnson Consumer Companies, Inc. | Compositions and methods for treating skin conditions |
| EP1140862A4 (en) | 1998-12-23 | 2004-07-28 | Bristol Myers Squibb Pharma Co | THROMBIN OR FACTOR Xa INHIBITORS |
| EA200100815A1 (en) | 1999-01-27 | 2002-08-29 | Орто-Макнейл Фармасьютикал, Инк. | PEPTIDILE HETEROCYCLIC KETONES USED AS TRIPTASE INHIBITORS |
| FR2795072B1 (en) * | 1999-06-15 | 2001-07-27 | Adir | NOVEL BICYCLIC DERIVATIVES OF AMINO-PYRAZINONES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| CA2401749A1 (en) * | 2000-03-23 | 2001-09-27 | Elan Pharmaceuticals, Inc. | Compounds and methods to treat alzheimer's disease |
| US6586418B2 (en) | 2000-06-29 | 2003-07-01 | Bristol-Myers Squibb Company | Thrombin or factor Xa inhibitors |
| US8431550B2 (en) | 2000-10-27 | 2013-04-30 | Johnson & Johnson Consumer Companies, Inc. | Topical anti-cancer compositions and methods of use thereof |
| FR2818277B1 (en) * | 2000-12-14 | 2003-01-24 | Servier Lab | NOVEL BICYCLIC DERIVATIVES OF AMINO-PYRAZINONES, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME |
| US7192615B2 (en) | 2001-02-28 | 2007-03-20 | J&J Consumer Companies, Inc. | Compositions containing legume products |
| CN1642550A (en) | 2002-02-14 | 2005-07-20 | 美瑞德生物工程公司 | Beta-sheet mimetics and composition and methods relating thereto |
| WO2003082197A2 (en) | 2002-03-22 | 2003-10-09 | Gpc Biotech Ag | Immunosuppressant compounds, methods and uses related thereto |
| BR112017006920A8 (en) | 2014-10-06 | 2023-03-07 | Quince Therapeutics Inc | GINGIPAINE LYSINE INHIBITORS |
| JO3637B1 (en) | 2015-04-28 | 2020-08-27 | Janssen Sciences Ireland Uc | Rsv antiviral pyrazolo- and triazolo-pyrimidine compounds |
| CA3004095A1 (en) | 2015-11-09 | 2017-05-18 | Cortexyme, Inc. | Inhibitors of arginine gingipain |
| TWI787202B (en) | 2016-09-16 | 2022-12-21 | 美商昆斯治療公司 | Ketone inhibitors of lysine gingipain |
| TW201932470A (en) | 2017-11-29 | 2019-08-16 | 愛爾蘭商健生科學愛爾蘭無限公司 | Pyrazolopyrimidines having activity against RSV |
| EA202091835A1 (en) | 2018-01-31 | 2020-10-20 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | CYCLOALKYL SUBSTITUTED PYRAZOLOPYRIMIDINES WITH AN ACTIVITY AGAINST RSV |
| AU2019260109B2 (en) | 2018-04-23 | 2023-07-13 | Janssen Sciences Ireland Unlimited Company | Heteroaromatic compounds having activity against RSV |
-
1995
- 1995-12-21 WO PCT/CA1995/000708 patent/WO1996019483A1/en not_active Application Discontinuation
- 1995-12-21 PL PL95320965A patent/PL320965A1/en unknown
- 1995-12-21 EE EE9700113A patent/EE9700113A/en unknown
- 1995-12-21 JP JP8519383A patent/JPH11508535A/en active Pending
- 1995-12-21 NZ NZ297360A patent/NZ297360A/en unknown
- 1995-12-21 CZ CZ971899A patent/CZ189997A3/en unknown
- 1995-12-21 EP EP95940923A patent/EP0802916A1/en not_active Ceased
- 1995-12-21 HU HU9800216A patent/HUT77651A/en unknown
- 1995-12-21 AU AU42505/96A patent/AU4250596A/en not_active Abandoned
- 1995-12-21 CN CN95197614A patent/CN1175259A/en active Pending
- 1995-12-21 CA CA002208772A patent/CA2208772A1/en not_active Abandoned
- 1995-12-21 AP APAP/P/1997/001004A patent/AP9701004A0/en unknown
- 1995-12-21 MD MD97-0253A patent/MD970253A/en unknown
- 1995-12-21 SK SK838-97A patent/SK83897A3/en unknown
- 1995-12-22 AU AU40628/95A patent/AU715378B2/en not_active Ceased
- 1995-12-22 IL IL11650395D patent/IL116503A0/en unknown
-
1997
- 1997-06-11 IS IS4504A patent/IS4504A/en unknown
- 1997-06-11 FI FI972466A patent/FI972466A/en unknown
- 1997-06-18 OA OA70029A patent/OA10493A/en unknown
- 1997-06-20 BG BG101647A patent/BG101647A/en unknown
- 1997-06-20 NO NO972892A patent/NO972892L/en unknown
- 1997-06-23 MX MX9704718A patent/MX9704718A/en unknown
- 1997-07-15 LV LVP-97-141A patent/LV12019B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL116503A0 (en) | 1996-03-31 |
| NO972892L (en) | 1997-08-20 |
| AU4062895A (en) | 1996-07-04 |
| CN1175259A (en) | 1998-03-04 |
| CA2208772A1 (en) | 1996-06-27 |
| WO1996019483A1 (en) | 1996-06-27 |
| MD970253A (en) | 1999-05-31 |
| AP9701004A0 (en) | 1997-07-31 |
| AU715378B2 (en) | 2000-02-03 |
| EE9700113A (en) | 1997-12-15 |
| BG101647A (en) | 1998-03-31 |
| HUT77651A (en) | 1998-07-28 |
| IS4504A (en) | 1997-06-11 |
| SK83897A3 (en) | 1998-05-06 |
| MX9704718A (en) | 1998-06-28 |
| PL320965A1 (en) | 1997-11-24 |
| LV12019B (en) | 1998-07-20 |
| FI972466A (en) | 1997-08-19 |
| EP0802916A1 (en) | 1997-10-29 |
| FI972466A0 (en) | 1997-06-11 |
| NZ297360A (en) | 2000-03-27 |
| JPH11508535A (en) | 1999-07-27 |
| NO972892D0 (en) | 1997-06-20 |
| LV12019A (en) | 1998-04-20 |
| OA10493A (en) | 2002-04-10 |
| CZ189997A3 (en) | 1998-09-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU4250596A (en) | Low molecular weight bicyclic thrombin inhibitors | |
| AU3832895A (en) | Thrombin inhibitors | |
| AU4875196A (en) | Novel thrombin inhibitors | |
| AU7497596A (en) | Thrombin inhibitors | |
| AU4269896A (en) | Fibronectin adhesion inhibitors | |
| AU7145294A (en) | Heterocyclic thrombin inhibitors | |
| AU1301697A (en) | Tyrosin-derivate as alpha-v-integrin inhibitors | |
| AU3941797A (en) | Novel thrombin inhibitors | |
| AU6734296A (en) | Bicyclic lactam derivatives as thrombin inhibitors | |
| AU2568897A (en) | Cyclic adhesion inhibitors | |
| AU6183494A (en) | Guanidinyl- or amidinyl-substituted heterocyclic thrombin inhibitors | |
| AU3551297A (en) | Polymerisation inhibitor | |
| AU1768497A (en) | Thrombin muteins as antidotes for thrombin inhibitors | |
| AU5682596A (en) | Low molecular weight bicyclic-area type thrombin inhibitors | |
| AU3396697A (en) | Thrombin inhibitor | |
| AU3042697A (en) | Thrombin inhibitors | |
| IL117437A0 (en) | Novel thrombin inhibitors | |
| AU1013997A (en) | Amylase inhibitors | |
| AU5526098A (en) | Bicyclic thrombin inhibitors | |
| AU2908197A (en) | Thrombin inhibitors | |
| AU4618197A (en) | Thrombin inhibitors | |
| AU2035997A (en) | Sealant-carrying articles | |
| GB9503136D0 (en) | Low molecular weight bicyclic thrombin inhibitors | |
| GB9510266D0 (en) | Low molecular weight bicyclic thrombin inhibitors | |
| GB9510267D0 (en) | Low molecular weight thiobicyclic thrombin inhibitors |