AU2832899A - Hydroxyethyl starch conjugate, method for the production thereof and pharmaceuticals containing the same - Google Patents

Hydroxyethyl starch conjugate, method for the production thereof and pharmaceuticals containing the same

Info

Publication number
AU2832899A
AU2832899A AU28328/99A AU2832899A AU2832899A AU 2832899 A AU2832899 A AU 2832899A AU 28328/99 A AU28328/99 A AU 28328/99A AU 2832899 A AU2832899 A AU 2832899A AU 2832899 A AU2832899 A AU 2832899A
Authority
AU
Australia
Prior art keywords
production
same
hydroxyethyl starch
pharmaceuticals containing
starch conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU28328/99A
Inventor
Peter Mareski
Ulrich Niedballa
Johannes Dr. Platzek
Bernd Dr. Raduchel
Hanns-Joachim Weinmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU2832899A publication Critical patent/AU2832899A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B31/00—Preparation of derivatives of starch
    • C08B31/08—Ethers
    • C08B31/12—Ethers having alkyl or cycloalkyl radicals substituted by heteroatoms, e.g. hydroxyalkyl or carboxyalkyl starch
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/12—Macromolecular compounds
    • A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
    • A61K49/128—Linear polymers, e.g. dextran, inulin, PEG comprising multiple complex or complex-forming groups, being either part of the linear polymeric backbone or being pending groups covalently linked to the linear polymeric backbone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AU28328/99A 1998-02-20 1999-02-09 Hydroxyethyl starch conjugate, method for the production thereof and pharmaceuticals containing the same Abandoned AU2832899A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1998108079 DE19808079A1 (en) 1998-02-20 1998-02-20 New hydroxyethyl starch conjugates useful as X-ray, NMR and blood-pool diagnostic agents, e.g. for diagnosis of tumors, cardiovascular disorders and inflammation
DE19808079 1998-02-20
PCT/EP1999/000853 WO1999042139A2 (en) 1998-02-20 1999-02-09 Hydroxyethyl starch conjugate, method for the production thereof and pharmaceuticals containing the same

Publications (1)

Publication Number Publication Date
AU2832899A true AU2832899A (en) 1999-09-06

Family

ID=7858971

Family Applications (1)

Application Number Title Priority Date Filing Date
AU28328/99A Abandoned AU2832899A (en) 1998-02-20 1999-02-09 Hydroxyethyl starch conjugate, method for the production thereof and pharmaceuticals containing the same

Country Status (3)

Country Link
AU (1) AU2832899A (en)
DE (1) DE19808079A1 (en)
WO (1) WO1999042139A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10112825A1 (en) 2001-03-16 2002-10-02 Fresenius Kabi De Gmbh HESylation of active ingredients in aqueous solution
DE10209822A1 (en) * 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Coupling of low molecular weight substances to a modified polysaccharide
DE10209821A1 (en) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Coupling of proteins to a modified polysaccharide
BR0314107A (en) 2002-09-11 2005-07-19 Fresenius Kabi De Gmbh Production method of hydroxyalkyl starch derivatives
AU2003273413A1 (en) 2002-10-08 2004-05-04 Fresenius Kabi Deutschland Gmbh Pharmaceutically active oligosaccharide conjugates
WO2005014655A2 (en) 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugates of hydroxyalkyl starch and a protein
AR048035A1 (en) 2004-03-11 2006-03-22 Fresenius Kabi De Gmbh CONJUGADOS DE ALMIDON DE HIDROXIALQUILO AND A PROTEIN, PREPARED BY REDUCING AMINATION
DE102007015282B4 (en) * 2007-03-29 2017-10-05 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Viscosity regulator, process for its preparation and its use
EP2070950A1 (en) 2007-12-14 2009-06-17 Fresenius Kabi Deutschland GmbH Hydroxyalkyl starch derivatives and process for their preparation
AU2012239933B2 (en) * 2011-04-06 2017-01-05 Cedars-Sinai Medical Center Polymalic acid based nanoconjugates for imaging
CN102321185B (en) * 2011-08-09 2012-12-19 武汉华科大生命科技有限公司 Synthesis method of middle-molecular-weight hydroxyethyl starch
RU2655810C2 (en) * 2016-10-12 2018-05-29 Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) Means for cerebral blood flow increase

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE465907B (en) * 1984-11-01 1991-11-18 Nyegaard & Co As DIAGNOSTIC AGENT CONTENT AND PARAMAGNETIC METAL
US5336762A (en) * 1985-11-18 1994-08-09 Access Pharmaceuticals, Inc. Polychelating agents for image and spectral enhancement (and spectral shift)
EP0250358A3 (en) * 1986-06-20 1988-10-05 Schering Aktiengesellschaft Novel complex compounds
GB8801646D0 (en) * 1988-01-26 1988-02-24 Nycomed As Chemical compounds
WO1990003190A1 (en) * 1988-09-29 1990-04-05 Ranney David F Methods and compositions for magnetic resonance imaging
JPH02261801A (en) * 1989-04-03 1990-10-24 Tetsuo Suami Low-viscosity iodinated hydroxyethylstarch and preparation thereof
AU8950291A (en) * 1990-10-16 1992-05-20 Biomedical Frontiers, Inc. Polymer-deferoxamine-ferric iron adducts for use in magnetic resonance imaging
US5330742A (en) * 1991-08-05 1994-07-19 Mallinckrodt Medical, Inc. Methods and compositions for magnetic resonance imaging
JP3854631B2 (en) * 1993-08-12 2006-12-06 アドバンスド・マグネティクス・インク Synthesis of superparamagnetic oxide colloids coated with polysaccharides

Also Published As

Publication number Publication date
DE19808079A1 (en) 1999-08-26
WO1999042139A3 (en) 1999-09-30
WO1999042139A2 (en) 1999-08-26

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase