AU2023331268A1 - Cycloalkyne derivative - Google Patents

Cycloalkyne derivative Download PDF

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Publication number
AU2023331268A1
AU2023331268A1 AU2023331268A AU2023331268A AU2023331268A1 AU 2023331268 A1 AU2023331268 A1 AU 2023331268A1 AU 2023331268 A AU2023331268 A AU 2023331268A AU 2023331268 A AU2023331268 A AU 2023331268A AU 2023331268 A1 AU2023331268 A1 AU 2023331268A1
Authority
AU
Australia
Prior art keywords
compound
chemical formula
mmol
formula
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2023331268A
Other languages
English (en)
Inventor
Takanori Aoki
Masahiko KINEBUCHI
Keiichi Masuya
Masatoshi Matsumoto
Yoshihide MIZUKOSHI
Kyosuke Ueda
Shuhei YAMAKOSHI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Peptidream Inc
Original Assignee
Peptidream Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peptidream Inc filed Critical Peptidream Inc
Publication of AU2023331268A1 publication Critical patent/AU2023331268A1/en
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2023331268A 2022-08-26 2023-08-25 Cycloalkyne derivative Pending AU2023331268A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2022135334 2022-08-26
JP2022-135334 2022-08-26
PCT/JP2023/030810 WO2024043341A1 (ja) 2022-08-26 2023-08-25 シクロアルキン誘導体

Publications (1)

Publication Number Publication Date
AU2023331268A1 true AU2023331268A1 (en) 2025-03-06

Family

ID=90013547

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2023331268A Pending AU2023331268A1 (en) 2022-08-26 2023-08-25 Cycloalkyne derivative

Country Status (6)

Country Link
EP (1) EP4578860A1 (https=)
JP (1) JPWO2024043341A1 (https=)
CN (1) CN120092006A (https=)
AU (1) AU2023331268A1 (https=)
IL (1) IL319133A (https=)
WO (1) WO2024043341A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025133522A (ja) * 2024-03-01 2025-09-11 国立大学法人 熊本大学 クリック反応素子ａｏｃｎ誘導体又はその塩

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7807619B2 (en) 2004-11-01 2010-10-05 The Regents Of The University Of California Compositions and methods for modification of biomolecules
US8258347B2 (en) * 2009-02-19 2012-09-04 University Of Georgia Research Foundation, Inc. Cyclopropenones and the photochemical generation of cyclic alkynes therefrom
US20180010126A1 (en) 2014-09-19 2018-01-11 Ionis Pharmaceuticals, Inc. Antisense compounds and uses thereof
JP2018039773A (ja) 2016-09-09 2018-03-15 克彦 友岡 含窒素９員環アルキン
NZ762505A (en) * 2017-09-29 2026-03-27 Daiichi Sankyo Co Ltd Antibody-pyrrolobenzodiazepine derivative conjugate
US12539292B2 (en) 2018-04-01 2026-02-03 Arvinas Operations, Inc. BRM targeting compounds and associated methods of use
JP7320821B2 (ja) 2018-08-10 2023-08-04 国立大学法人九州大学 化合物、高分子化合物及び高分子化合物の製造方法
WO2021167107A1 (ja) 2020-02-22 2021-08-26 Ｊｃｒファーマ株式会社 ヒトトランスフェリンレセプター結合ペプチド
JP2024512810A (ja) * 2021-04-05 2024-03-19 ダナ－ファーバー キャンサー インスティテュート，インコーポレイテッド クリック／非クリック適用に適した生体直交型反応

Also Published As

Publication number Publication date
JPWO2024043341A1 (https=) 2024-02-29
IL319133A (en) 2025-04-01
WO2024043341A1 (ja) 2024-02-29
EP4578860A1 (en) 2025-07-02
CN120092006A (zh) 2025-06-03

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