AU2023249146A1 - Salt forms and solvates of mci-1 antagonists - Google Patents

Salt forms and solvates of mci-1 antagonists Download PDF

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Publication number
AU2023249146A1
AU2023249146A1 AU2023249146A AU2023249146A AU2023249146A1 AU 2023249146 A1 AU2023249146 A1 AU 2023249146A1 AU 2023249146 A AU2023249146 A AU 2023249146A AU 2023249146 A AU2023249146 A AU 2023249146A AU 2023249146 A1 AU2023249146 A1 AU 2023249146A1
Authority
AU
Australia
Prior art keywords
crystalline form
amg
xrpd pattern
radiation
crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2023249146A
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English (en)
Inventor
Melanie BEVILL
Travis Houston
Courtney Johnson
Henry Morrison
Stephan D. Parent
Jason S. Tedrow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of AU2023249146A1 publication Critical patent/AU2023249146A1/en
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2023249146A 2022-04-05 2023-04-05 Salt forms and solvates of mci-1 antagonists Pending AU2023249146A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263327659P 2022-04-05 2022-04-05
US63/327,659 2022-04-05
PCT/US2023/017504 WO2023196360A1 (en) 2022-04-05 2023-04-05 Salt forms and solvates of mci-1 antagonists

Publications (1)

Publication Number Publication Date
AU2023249146A1 true AU2023249146A1 (en) 2024-10-10

Family

ID=86386785

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2023249146A Pending AU2023249146A1 (en) 2022-04-05 2023-04-05 Salt forms and solvates of mci-1 antagonists

Country Status (9)

Country Link
US (1) US12351588B2 (https=)
EP (1) EP4504737A1 (https=)
JP (1) JP2025513774A (https=)
AU (1) AU2023249146A1 (https=)
CA (1) CA3254998A1 (https=)
MX (1) MX2024012192A (https=)
TW (1) TW202404983A (https=)
UY (1) UY40217A (https=)
WO (1) WO2023196360A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4519271A1 (en) 2022-05-04 2025-03-12 Gilead Sciences, Inc. Salts and polymorphs of certain mcl-1 inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO3474B1 (ar) 2014-08-29 2020-07-05 Amgen Inc مشتقات تيتراهيدرونافثالين التي تثبط بروتين mcl-1

Also Published As

Publication number Publication date
CA3254998A1 (en) 2023-10-12
MX2024012192A (es) 2024-11-08
US20230312602A1 (en) 2023-10-05
TW202404983A (zh) 2024-02-01
JP2025513774A (ja) 2025-04-30
US12351588B2 (en) 2025-07-08
WO2023196360A1 (en) 2023-10-12
EP4504737A1 (en) 2025-02-12
UY40217A (es) 2023-10-31

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