AU2022373543A1 - Anti-mesothelin nanobodies and use thereof - Google Patents

Anti-mesothelin nanobodies and use thereof Download PDF

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Publication number
AU2022373543A1
AU2022373543A1 AU2022373543A AU2022373543A AU2022373543A1 AU 2022373543 A1 AU2022373543 A1 AU 2022373543A1 AU 2022373543 A AU2022373543 A AU 2022373543A AU 2022373543 A AU2022373543 A AU 2022373543A AU 2022373543 A1 AU2022373543 A1 AU 2022373543A1
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Australia
Prior art keywords
antigen
nanobody
binding fragment
sequence
seq
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AU2022373543A
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Inventor
Zhiyuan Li
Xiaoniu MIAO
Fan Wu
Zhenqing ZHANG
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Biotheus Inc
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Biotheus Inc
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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    • C07K16/303—Liver or Pancreas
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AU2022373543A 2021-10-18 2022-10-13 Anti-mesothelin nanobodies and use thereof Pending AU2022373543A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202111208871.9 2021-10-18
CN202111208871.9A CN115991782A (zh) 2021-10-18 2021-10-18 抗间皮素纳米抗体及其用途
PCT/CN2022/125135 WO2023066133A1 (zh) 2021-10-18 2022-10-13 抗间皮素纳米抗体及其用途

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AU2022373543A1 true AU2022373543A1 (en) 2024-05-16

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US (1) US20240417452A1 (https=)
EP (1) EP4421095A4 (https=)
JP (1) JP2024542944A (https=)
KR (1) KR20240099295A (https=)
CN (1) CN115991782A (https=)
AU (1) AU2022373543A1 (https=)
CA (1) CA3235697A1 (https=)
MX (1) MX2024004702A (https=)
WO (1) WO2023066133A1 (https=)

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CN116466097B (zh) * 2023-06-14 2023-08-29 天津市协和医药科技集团有限公司 一种人胰岛素检测试剂盒
CN117843793B (zh) * 2024-03-07 2024-07-09 深圳真实生物医药科技有限公司 抗间皮素抗体、抗原结合片段及其用途

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CN103819559B (zh) * 2013-12-10 2016-02-24 中国科学院武汉病毒研究所 一种抗间皮素纳米抗体及其编码基因和该纳米抗体的用途
ES2918501T3 (es) * 2013-12-19 2022-07-18 Novartis Ag Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
CN108129566B (zh) * 2017-12-31 2021-05-11 中国科学院武汉病毒研究所 靶向间皮素的c-型单域抗体及其制备方法与应用
GB201811415D0 (en) * 2018-07-12 2018-08-29 F Star Beta Ltd Anti-Mesothelin Anti bodies
CN109467605A (zh) * 2018-11-07 2019-03-15 南京卡提医学科技有限公司 嵌合抗原受体DAP12-T2A-CD8α-MSLN scFv-NKp44及其用途
KR20220035908A (ko) * 2019-06-19 2022-03-22 실버백 테라퓨틱스, 인크. 항-메소텔린 항체 및 이의 면역접합체
CN110698562B (zh) * 2019-10-31 2022-10-25 浙江蓝盾药业有限公司 抗人msln单克隆抗体

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