AU2022370129A1 - Method, system, and computer-readable medium for operating and monitoring the cleaning of sample processing instruments - Google Patents
Method, system, and computer-readable medium for operating and monitoring the cleaning of sample processing instruments Download PDFInfo
- Publication number
- AU2022370129A1 AU2022370129A1 AU2022370129A AU2022370129A AU2022370129A1 AU 2022370129 A1 AU2022370129 A1 AU 2022370129A1 AU 2022370129 A AU2022370129 A AU 2022370129A AU 2022370129 A AU2022370129 A AU 2022370129A AU 2022370129 A1 AU2022370129 A1 AU 2022370129A1
- Authority
- AU
- Australia
- Prior art keywords
- cleaning
- sample
- carryover
- monitoring
- flow cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004140 cleaning Methods 0.000 title claims abstract description 252
- 238000012544 monitoring process Methods 0.000 title claims abstract description 166
- 238000012545 processing Methods 0.000 title claims abstract description 125
- 238000000034 method Methods 0.000 title claims abstract description 124
- 239000002245 particle Substances 0.000 claims abstract description 74
- 239000012459 cleaning agent Substances 0.000 claims abstract description 64
- 238000005259 measurement Methods 0.000 claims abstract description 22
- 239000012530 fluid Substances 0.000 claims description 85
- 230000008569 process Effects 0.000 claims description 38
- 230000000694 effects Effects 0.000 claims description 19
- 238000005086 pumping Methods 0.000 claims description 12
- 230000004044 response Effects 0.000 claims description 12
- 239000007788 liquid Substances 0.000 claims description 11
- 238000004891 communication Methods 0.000 claims description 9
- 230000003287 optical effect Effects 0.000 claims description 8
- 239000002105 nanoparticle Substances 0.000 claims description 5
- 239000000523 sample Substances 0.000 description 296
- 210000004027 cell Anatomy 0.000 description 83
- 238000010586 diagram Methods 0.000 description 15
- 230000015654 memory Effects 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
- 238000001514 detection method Methods 0.000 description 6
- 239000002699 waste material Substances 0.000 description 6
- 230000001276 controlling effect Effects 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 238000004590 computer program Methods 0.000 description 3
- 230000002572 peristaltic effect Effects 0.000 description 3
- 239000011324 bead Substances 0.000 description 2
- 239000012472 biological sample Substances 0.000 description 2
- 210000001808 exosome Anatomy 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- -1 for example Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000002102 nanobead Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 238000013024 troubleshooting Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1425—Optical investigation techniques, e.g. flow cytometry using an analyser being characterised by its control arrangement
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L13/00—Cleaning or rinsing apparatus
- B01L13/02—Cleaning or rinsing apparatus for receptacle or instruments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N15/1409—Handling samples, e.g. injecting samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/15—Preventing contamination of the components of the optical system or obstruction of the light path
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00594—Quality control, including calibration or testing of components of the analyser
- G01N35/00613—Quality control
- G01N35/00623—Quality control of instruments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1026—Recognising analyser failures, e.g. bubbles; Quality control for particle analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1418—Eliminating clogging of debris
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Quality & Reliability (AREA)
- Sampling And Sample Adjustment (AREA)
- Cleaning In General (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111223982.7 | 2021-10-20 | ||
| CN202111223982.7A CN115990591A (zh) | 2021-10-20 | 2021-10-20 | 运行和监测样本处理仪的清洗的方法和系统及样本处理仪 |
| PCT/CN2022/113006 WO2023065796A1 (en) | 2021-10-20 | 2022-08-17 | Method, system, and computer-readable medium for operating and monitoring the cleaning of sample processing instruments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2022370129A1 true AU2022370129A1 (en) | 2024-03-07 |
Family
ID=83151484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2022370129A Pending AU2022370129A1 (en) | 2021-10-20 | 2022-08-17 | Method, system, and computer-readable medium for operating and monitoring the cleaning of sample processing instruments |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20240418625A1 (https=) |
| EP (1) | EP4419888A1 (https=) |
| JP (1) | JP2024537977A (https=) |
| KR (1) | KR20240089782A (https=) |
| CN (1) | CN115990591A (https=) |
| AU (1) | AU2022370129A1 (https=) |
| CA (1) | CA3234205A1 (https=) |
| WO (1) | WO2023065796A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4551340A2 (en) * | 2023-06-09 | 2025-05-14 | Beckman Coulter Biotechnology (Suzhou) Co., Ltd. | Method for cleaning sampling pipeline of sample processor, pipeline system for implementing the method, and sample processor |
| US20250137905A1 (en) * | 2023-10-27 | 2025-05-01 | Becton, Dickinson And Company | Fluid Supply Systems Having a Flow Control Circuit and Single Fluidic Connection, and Methods of Use Thereof |
| WO2025188886A1 (en) | 2024-03-06 | 2025-09-12 | Beckman Coulter, Inc. | Carryover monitor for validation of flow cytometer cleaning cycle |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3507325B2 (ja) * | 1998-02-26 | 2004-03-15 | ロッシュ ディアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 試料分析装置および試料分析方法 |
| JP6085419B2 (ja) * | 2012-03-30 | 2017-02-22 | シスメックス株式会社 | 検体分析装置 |
| US20210217518A1 (en) * | 2018-02-06 | 2021-07-15 | Diba Industries, Inc. | System and method for providing fluidic performance characteristics to a diagnostic platform |
| US10828655B2 (en) * | 2018-08-07 | 2020-11-10 | Deere & Company | Residue detection system |
| US12025626B2 (en) * | 2019-07-25 | 2024-07-02 | Hitachi High-Tech Corporation | Specimen analyzer |
| JP7541751B2 (ja) * | 2020-01-22 | 2024-08-29 | シンクサイト株式会社 | フローサイトメータ用フローセルおよびフローサイトメータ用フローセルの洗浄方法 |
| CN112452959B (zh) * | 2020-09-22 | 2022-07-01 | 潍坊嘉腾液压技术有限公司 | 一种管路清洗装置及清洗方法 |
-
2021
- 2021-10-20 CN CN202111223982.7A patent/CN115990591A/zh active Pending
-
2022
- 2022-08-17 EP EP22761945.9A patent/EP4419888A1/en active Pending
- 2022-08-17 CA CA3234205A patent/CA3234205A1/en active Pending
- 2022-08-17 AU AU2022370129A patent/AU2022370129A1/en active Pending
- 2022-08-17 WO PCT/CN2022/113006 patent/WO2023065796A1/en not_active Ceased
- 2022-08-17 US US18/702,316 patent/US20240418625A1/en active Pending
- 2022-08-17 KR KR1020247016044A patent/KR20240089782A/ko active Pending
- 2022-08-17 JP JP2024518642A patent/JP2024537977A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2024537977A (ja) | 2024-10-18 |
| CA3234205A1 (en) | 2023-04-27 |
| CN115990591A (zh) | 2023-04-21 |
| EP4419888A1 (en) | 2024-08-28 |
| US20240418625A1 (en) | 2024-12-19 |
| WO2023065796A1 (en) | 2023-04-27 |
| KR20240089782A (ko) | 2024-06-20 |
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