AU2022325543A1 - Small molecule sting antagonists - Google Patents
Small molecule sting antagonists Download PDFInfo
- Publication number
- AU2022325543A1 AU2022325543A1 AU2022325543A AU2022325543A AU2022325543A1 AU 2022325543 A1 AU2022325543 A1 AU 2022325543A1 AU 2022325543 A AU2022325543 A AU 2022325543A AU 2022325543 A AU2022325543 A AU 2022325543A AU 2022325543 A1 AU2022325543 A1 AU 2022325543A1
- Authority
- AU
- Australia
- Prior art keywords
- optionally substituted
- benzo
- dihydro
- urea
- indol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07—ORGANIC CHEMISTRY
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
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| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| CN102516153B (zh) * | 2011-12-14 | 2014-03-12 | 南京工业大学 | 5-氟吲哚-2-酮-3-脲类化合物及其制备方法和应用 |
| US8969325B2 (en) * | 2011-12-19 | 2015-03-03 | Abbvie Inc. | TRPV1 antagonists |
| US20200138827A1 (en) * | 2017-06-22 | 2020-05-07 | Curadev Pharma Limited | Small molecule modulators of human sting |
| UA125730C2 (uk) | 2017-06-22 | 2022-05-25 | Курадев Фарма Лімітед | Низькомолекулярні модулятори sting людини |
| WO2019243823A1 (en) * | 2018-06-21 | 2019-12-26 | Curadev Pharma Limited | Azaheterocyclic small molecule modulators of human sting |
| CN120004785A (zh) * | 2018-07-03 | 2025-05-16 | 诺华制药股份有限公司 | 用于治疗与sting活性有关的疾病的化合物和组合物 |
| UY38905A (es) * | 2019-10-03 | 2021-04-30 | Ifm Due Inc | Compuestos y composiciones para tratar afecciones asociadas con la actividad de sting |
| CA3166358A1 (en) * | 2020-02-12 | 2021-08-19 | Monali BANERJEE | Small molecule sting antagonists |
-
2022
- 2022-08-11 WO PCT/IB2022/057490 patent/WO2023017451A1/en not_active Ceased
- 2022-08-11 EP EP22772571.0A patent/EP4384267A1/en active Pending
- 2022-08-11 JP JP2024508024A patent/JP2024529088A/ja active Pending
- 2022-08-11 CA CA3228528A patent/CA3228528A1/en active Pending
- 2022-08-11 TW TW111130171A patent/TW202321232A/zh unknown
- 2022-08-11 AU AU2022325543A patent/AU2022325543A1/en active Pending
- 2022-08-11 KR KR1020247007587A patent/KR20240046742A/ko active Pending
- 2022-08-11 IL IL310705A patent/IL310705A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023017451A1 (en) | 2023-02-16 |
| CA3228528A1 (en) | 2023-02-16 |
| TW202321232A (zh) | 2023-06-01 |
| JP2024529088A (ja) | 2024-08-01 |
| EP4384267A1 (en) | 2024-06-19 |
| IL310705A (en) | 2024-04-01 |
| KR20240046742A (ko) | 2024-04-09 |
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