AU2022307546A1 - Treatment of varicose veins with piezo type mechanosensitive ion channel component 1 (piezo1) agonists - Google Patents

Treatment of varicose veins with piezo type mechanosensitive ion channel component 1 (piezo1) agonists Download PDF

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Publication number
AU2022307546A1
AU2022307546A1 AU2022307546A AU2022307546A AU2022307546A1 AU 2022307546 A1 AU2022307546 A1 AU 2022307546A1 AU 2022307546 A AU2022307546 A AU 2022307546A AU 2022307546 A AU2022307546 A AU 2022307546A AU 2022307546 A1 AU2022307546 A1 AU 2022307546A1
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AU
Australia
Prior art keywords
seq
complement
position corresponding
thymine
piezol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2022307546A
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English (en)
Inventor
Goncalo Abecasis
Joshua Backman
Aris BARAS
Manuel Allen Revez FERREIRA
Alexander LI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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Publication date
Application filed by Regeneron Pharmaceuticals Inc filed Critical Regeneron Pharmaceuticals Inc
Publication of AU2022307546A1 publication Critical patent/AU2022307546A1/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2022307546A 2021-07-08 2022-07-05 Treatment of varicose veins with piezo type mechanosensitive ion channel component 1 (piezo1) agonists Pending AU2022307546A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163219462P 2021-07-08 2021-07-08
US63/219,462 2021-07-08
PCT/US2022/073441 WO2023283560A1 (en) 2021-07-08 2022-07-05 Treatment of varicose veins with piezo type mechanosensitive ion channel component 1 (piezo1) agonists

Publications (1)

Publication Number Publication Date
AU2022307546A1 true AU2022307546A1 (en) 2024-01-04

Family

ID=82748409

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2022307546A Pending AU2022307546A1 (en) 2021-07-08 2022-07-05 Treatment of varicose veins with piezo type mechanosensitive ion channel component 1 (piezo1) agonists

Country Status (10)

Country Link
US (1) US20230041060A1 (https=)
EP (1) EP4367266A1 (https=)
JP (1) JP2024524554A (https=)
KR (1) KR20240049797A (https=)
CN (1) CN121175436A (https=)
AU (1) AU2022307546A1 (https=)
CA (1) CA3225855A1 (https=)
IL (1) IL309694A (https=)
MX (1) MX2023015276A (https=)
WO (1) WO2023283560A1 (https=)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK4317456T3 (da) * 2019-02-18 2025-09-08 Regeneron Pharma Varianter af mekanoensitiv ionkanalkomponent 1 af piezotypen (piezo1) og anvendelser deraf

Also Published As

Publication number Publication date
WO2023283560A1 (en) 2023-01-12
CA3225855A1 (en) 2023-01-12
MX2023015276A (es) 2024-04-03
JP2024524554A (ja) 2024-07-05
EP4367266A1 (en) 2024-05-15
IL309694A (en) 2024-02-01
CN121175436A (zh) 2025-12-19
US20230041060A1 (en) 2023-02-09
KR20240049797A (ko) 2024-04-17

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