AU2021383613A1 - Inhaled imatinib for pulmonary hypertension field - Google Patents
Inhaled imatinib for pulmonary hypertension field Download PDFInfo
- Publication number
- AU2021383613A1 AU2021383613A1 AU2021383613A AU2021383613A AU2021383613A1 AU 2021383613 A1 AU2021383613 A1 AU 2021383613A1 AU 2021383613 A AU2021383613 A AU 2021383613A AU 2021383613 A AU2021383613 A AU 2021383613A AU 2021383613 A1 AU2021383613 A1 AU 2021383613A1
- Authority
- AU
- Australia
- Prior art keywords
- imatinib
- substituted
- dry powder
- composition
- microns
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063114781P | 2020-11-17 | 2020-11-17 | |
US63/114,781 | 2020-11-17 | ||
PCT/US2021/059553 WO2022108939A1 (fr) | 2020-11-17 | 2021-11-16 | Imatinib inhalé pour le domaine de l'hypertension pulmonaire |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2021383613A1 true AU2021383613A1 (en) | 2023-07-06 |
Family
ID=78845039
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2021383613A Pending AU2021383613A1 (en) | 2020-11-17 | 2021-11-16 | Inhaled imatinib for pulmonary hypertension field |
Country Status (9)
Country | Link |
---|---|
US (1) | US20220152025A1 (fr) |
EP (1) | EP4247337A1 (fr) |
JP (1) | JP2023550407A (fr) |
KR (1) | KR20230131179A (fr) |
CN (1) | CN116916889A (fr) |
AU (1) | AU2021383613A1 (fr) |
CA (1) | CA3199324A1 (fr) |
IL (1) | IL302994A (fr) |
WO (1) | WO2022108939A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023147868A1 (fr) * | 2022-02-04 | 2023-08-10 | Justus-Liebig-Universität Giessen | Imatinib inhalé pour le traitement de l'hypertension pulmonaire |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5521184A (en) | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
US6428771B1 (en) * | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
MX2008010721A (es) * | 2006-02-22 | 2008-09-01 | Mannkind Corp | Un metodo para mejorar las propiedades farmaceuticas de microparticulas que contienen dicetopiperazina y un agente activo. |
BRPI0602338A (pt) * | 2006-03-24 | 2007-12-11 | Univ Kyushu Nat Univ Corp | compostos orgánicos |
CA2654492C (fr) | 2006-05-15 | 2017-06-27 | United Therapeutics Corporation | Administration de treprostinil utilisant un inhalateur a dose mesuree |
EP3281663B8 (fr) | 2008-06-13 | 2022-09-21 | MannKind Corporation | Inhalateur de poudre sèche alimenté par la respiration pour l'administration de médicaments |
DE102008036864A1 (de) | 2008-08-07 | 2010-02-18 | Lfk-Lenkflugkörpersysteme Gmbh | Stranggepresstes Formteil sowie Verfahren zur Herstellung eines solchen Formteiles |
MX2011001668A (es) | 2008-08-13 | 2011-03-25 | Novartis Ag | Tratamiento de hipertension arterial pulmonar. |
MX2011009682A (es) | 2009-03-18 | 2011-10-17 | Mannkind Corp | Adaptador de inhalador para un aparato de difraccion de laser y metodo para medir la distribucion de tamaño de particula. |
EP2496295A1 (fr) | 2009-11-03 | 2012-09-12 | MannKind Corporation | Appareil et méthode de simulation d'efforts d'inhalation |
EP3587404B1 (fr) * | 2013-03-15 | 2022-07-13 | MannKind Corporation | Compositions de dicétopipérazine microcristallines, procédés de préparation et leur utilisation |
WO2015017728A1 (fr) * | 2013-07-31 | 2015-02-05 | Windward Pharma, Inc. | Composés inhibiteurs de tyrosine kinase en aérosol et leurs utilisations |
US20190321290A1 (en) * | 2016-01-29 | 2019-10-24 | Mannkind Corporation | Composition and method for inhalation |
GB201610044D0 (en) * | 2016-06-08 | 2016-07-20 | Ucb Biopharma Sprl | Antibodies |
CA3102967A1 (fr) | 2018-06-07 | 2019-12-12 | Mannkind Corporation | Composition et procede d'inhalation |
JP2022532431A (ja) * | 2019-05-16 | 2022-07-14 | エアロベイト セラピューティクス, インコーポレイテッド | イマチニブ製剤、その製造および使用 |
-
2021
- 2021-11-16 EP EP21824194.1A patent/EP4247337A1/fr active Pending
- 2021-11-16 WO PCT/US2021/059553 patent/WO2022108939A1/fr active Application Filing
- 2021-11-16 CN CN202180090988.3A patent/CN116916889A/zh active Pending
- 2021-11-16 US US17/528,011 patent/US20220152025A1/en active Pending
- 2021-11-16 AU AU2021383613A patent/AU2021383613A1/en active Pending
- 2021-11-16 IL IL302994A patent/IL302994A/en unknown
- 2021-11-16 CA CA3199324A patent/CA3199324A1/fr active Pending
- 2021-11-16 KR KR1020237020139A patent/KR20230131179A/ko unknown
- 2021-11-16 JP JP2023530064A patent/JP2023550407A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL302994A (en) | 2023-07-01 |
JP2023550407A (ja) | 2023-12-01 |
CA3199324A1 (fr) | 2022-05-27 |
KR20230131179A (ko) | 2023-09-12 |
CN116916889A (zh) | 2023-10-20 |
EP4247337A1 (fr) | 2023-09-27 |
WO2022108939A1 (fr) | 2022-05-27 |
US20220152025A1 (en) | 2022-05-19 |
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