AU2021325149A1 - Lyophilized live bordetella vaccines - Google Patents

Lyophilized live bordetella vaccines Download PDF

Info

Publication number
AU2021325149A1
AU2021325149A1 AU2021325149A AU2021325149A AU2021325149A1 AU 2021325149 A1 AU2021325149 A1 AU 2021325149A1 AU 2021325149 A AU2021325149 A AU 2021325149A AU 2021325149 A AU2021325149 A AU 2021325149A AU 2021325149 A1 AU2021325149 A1 AU 2021325149A1
Authority
AU
Australia
Prior art keywords
bacteria
bordetella
bpze1
lyophilized
lyophilization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2021325149A
Other languages
English (en)
Inventor
Marcel THALEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iliad Biotechnologies Inc
Original Assignee
Iliad Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iliad Biotechnologies Inc filed Critical Iliad Biotechnologies Inc
Publication of AU2021325149A1 publication Critical patent/AU2021325149A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04Preserving or maintaining viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2021325149A 2020-08-14 2021-08-15 Lyophilized live bordetella vaccines Pending AU2021325149A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063066020P 2020-08-14 2020-08-14
US63/066,020 2020-08-14
PCT/US2021/046055 WO2022036298A1 (en) 2020-08-14 2021-08-15 Lyophilized live bordetella vaccines

Publications (1)

Publication Number Publication Date
AU2021325149A1 true AU2021325149A1 (en) 2023-03-02

Family

ID=80247370

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2021325149A Pending AU2021325149A1 (en) 2020-08-14 2021-08-15 Lyophilized live bordetella vaccines

Country Status (12)

Country Link
US (1) US20230173053A1 (cg-RX-API-DMAC7.html)
EP (1) EP4196155A4 (cg-RX-API-DMAC7.html)
JP (1) JP7809362B2 (cg-RX-API-DMAC7.html)
KR (1) KR20230051186A (cg-RX-API-DMAC7.html)
CN (1) CN116322756A (cg-RX-API-DMAC7.html)
AU (1) AU2021325149A1 (cg-RX-API-DMAC7.html)
BR (1) BR112023002549A2 (cg-RX-API-DMAC7.html)
CA (1) CA3187934A1 (cg-RX-API-DMAC7.html)
CL (1) CL2023000451A1 (cg-RX-API-DMAC7.html)
CO (1) CO2023002823A2 (cg-RX-API-DMAC7.html)
MX (1) MX2023001905A (cg-RX-API-DMAC7.html)
WO (1) WO2022036298A1 (cg-RX-API-DMAC7.html)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2215033C2 (ru) * 2001-06-27 2003-10-27 Научно-исследовательский институт микробиологии МО РФ Способ получения концентрата микробных клеток в производстве чумных вакцин
EP1708747A2 (en) * 2004-01-15 2006-10-11 Intervet International BV Non-animal origin stabilizers and processes for producing the same
US9119804B2 (en) 2006-03-10 2015-09-01 Institut Pasteur De Lille Live attenuated bordetella strains as a single dose vaccine against whooping cough
EP2722338A1 (en) 2012-10-17 2014-04-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Novel recombinant Bordetella strains
AR097762A1 (es) * 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
EP4541809A3 (en) 2016-03-29 2025-06-25 Institut Pasteur de Lille Mutant bordetella strains and methods of use
RU2709657C2 (ru) * 2017-08-07 2019-12-19 федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации (ФГБУ "НИЦЭМ им. Н.Ф. Гамалеи" Минздрава России) Способ лиофильного высушивания аттенуированных бактерий B. pertussis, аттенуированная бактерия B. pertussis, штамм аттенуированных бактерий B. Pertussis, вакцина, лиофилизированный вакцинный препарат
WO2020049133A1 (en) 2018-09-05 2020-03-12 National University Of Singapore Adenylate cyclase catalytic domain deficient bordetella strains

Also Published As

Publication number Publication date
US20230173053A1 (en) 2023-06-08
CA3187934A1 (en) 2022-02-17
JP7809362B2 (ja) 2026-02-02
WO2022036298A1 (en) 2022-02-17
JP2023540453A (ja) 2023-09-25
CN116322756A (zh) 2023-06-23
CL2023000451A1 (es) 2023-10-20
EP4196155A1 (en) 2023-06-21
KR20230051186A (ko) 2023-04-17
MX2023001905A (es) 2023-03-13
EP4196155A4 (en) 2025-03-19
CO2023002823A2 (es) 2023-03-27
BR112023002549A2 (pt) 2023-03-07

Similar Documents

Publication Publication Date Title
CN102224237B (zh) 使用β-丙内酯(BLP)进行最终灭活的细菌菌影(BG)生产方法
US12303538B2 (en) High potency stable formulations of vaginal lactobacillus
US11447738B2 (en) Methods and compositions for preserving bacteria
EP3768820B1 (en) A method for lyophilizing live vaccine strains of francisella tularensis
CN107513506B (zh) 猪肺炎支原体、疫苗组合物及其应用
US20250213669A1 (en) Attenuated bordetella bronchiseptica strains, oral vaccines containing the attenuated strains, and methods of making & use thereof
RU1066074C (ru) Вакцина против псевдомоноза пушных зверей, преимущественно норок, способ ее получения и способ профилактики псевдомоноза пушных зверей, преимущественно норок
US20230173053A1 (en) Lyophilized Live Bordetella Vaccines
RU2855019C1 (ru) Лиофилизированные вакцины, содержащие живые бактерии рода Bordetella
CN116832149B (zh) 一种绵羊肺炎支原体、丝状支原体和d型多杀性巴氏杆菌三联灭活疫苗及制备方法
CN113046271B (zh) 一株兔f型多杀性巴氏杆菌及其在制备灭活疫苗中的应用
EP2280725B1 (en) Vaccine for protection against haemophilus parasuis serotype 4 in piglets
CN114146171A (zh) 一种猪萎缩性鼻炎灭活疫苗及其制备方法
HK40095547A (zh) 经冻干的活鲍特菌属疫苗
CN115814070A (zh) 一种副嗜血杆菌病疫苗及其制备方法和应用
KR101210082B1 (ko) 돼지 다발성 장막염 예방용 백신 조성물 및 그 제조방법
KR101209964B1 (ko) 돼지 다발성 장막염 예방용 백신 조성물 및 그 제조방법
Zweygarth et al. Experimental use of the attenuated Ehrlichia ruminantium (Welgevonden) vaccine in Merino sheep and Angora goats
NL8020132A (nl) Een vaccin voor de bestrijding van pleuropneumonie bij varkens en een werkwijze en een substraat voor de aerobe fermentatie van haemophilus pleuropneumoniae.
RU2709657C2 (ru) Способ лиофильного высушивания аттенуированных бактерий B. pertussis, аттенуированная бактерия B. pertussis, штамм аттенуированных бактерий B. Pertussis, вакцина, лиофилизированный вакцинный препарат
RU2325437C1 (ru) Аттенуированный штамм вируса оспы коз
RU2544951C1 (ru) АТТЕНУИРОВАННЫЙ ШТАММ Bacillus anthracis ДЛЯ РАЗРАБОТКИ СРЕДСТВ СПЕЦИФИЧЕСКОЙ ПРОФИЛАКТИКИ СИБИРСКОЙ ЯЗВЫ
JP5121230B2 (ja) Q熱のワクチン製剤および該ワクチン製剤の製造方法
CN121852301A (zh) 一种支气管败血波氏杆菌弱毒株及其应用
CN108018228A (zh) 一株大肠杆菌o157:h7弱毒株及其应用

Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: TO AMEND THE APPLICANT NAME TO ILIAD BIOTECHNOLOGIES, INC.