AU2021274173A1 - Controlled flow infusion microvascular dysfunction diagnostic and therapy - Google Patents

Controlled flow infusion microvascular dysfunction diagnostic and therapy Download PDF

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Publication number
AU2021274173A1
AU2021274173A1 AU2021274173A AU2021274173A AU2021274173A1 AU 2021274173 A1 AU2021274173 A1 AU 2021274173A1 AU 2021274173 A AU2021274173 A AU 2021274173A AU 2021274173 A AU2021274173 A AU 2021274173A AU 2021274173 A1 AU2021274173 A1 AU 2021274173A1
Authority
AU
Australia
Prior art keywords
pressure
infusion
occlusion
flow rates
resistance parameter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2021274173A
Other languages
English (en)
Inventor
Oliver BLUDAU
Sabrina FREY
Jon Helge Hoem
Robert S. Schwartz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corflow Therapeutics AG
Original Assignee
Corflow Therapeutics AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corflow Therapeutics AG filed Critical Corflow Therapeutics AG
Publication of AU2021274173A1 publication Critical patent/AU2021274173A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
    • A61B5/02152—Measuring pressure in heart or blood vessels by means inserted into the body specially adapted for venous pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • A61B5/6853—Catheters with a balloon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247—Pressure sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M2005/16863—Occlusion detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
AU2021274173A 2020-05-22 2021-05-21 Controlled flow infusion microvascular dysfunction diagnostic and therapy Pending AU2021274173A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063029152P 2020-05-22 2020-05-22
US63/029,152 2020-05-22
PCT/IB2021/054453 WO2021234670A1 (en) 2020-05-22 2021-05-21 Controlled flow infusion microvascular dysfunction diagnostic and therapy

Publications (1)

Publication Number Publication Date
AU2021274173A1 true AU2021274173A1 (en) 2022-12-22

Family

ID=76197501

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2021274173A Pending AU2021274173A1 (en) 2020-05-22 2021-05-21 Controlled flow infusion microvascular dysfunction diagnostic and therapy

Country Status (6)

Country Link
US (1) US20210361170A1 (https=)
EP (1) EP4153039B1 (https=)
JP (1) JP7773483B2 (https=)
AU (1) AU2021274173A1 (https=)
CA (1) CA3179588A1 (https=)
WO (1) WO2021234670A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11786140B2 (en) 2019-08-21 2023-10-17 Corflow Therapeutics Ag Controlled-flow infusion catheter and method
WO2019060421A1 (en) 2017-09-19 2019-03-28 Jon Helge Hoem INTRACORONARY MICROVASCULAR OBSTRUCTION CHARACTERIZATION (MVO) AND MYOCARDIAL INFARCTION
US12100516B2 (en) 2018-05-31 2024-09-24 Corflow Therapeutics Ag Microfluidic coronary circulatory model
JP2022501115A (ja) 2018-09-21 2022-01-06 コルフロウ セラピューティクス アーゲー 微小血管機能障害の査定のための装置
JP7679105B2 (ja) * 2020-06-22 2025-05-19 コロヴェンティス リサーチ エービー 微小血管抵抗予備能を決定するためのシステムおよび方法
US20220218210A1 (en) 2021-01-11 2022-07-14 Corflow Therapeutics Ag Apparatus and method for determining and/or treating microvascular obstruction
CN115252963B (zh) * 2022-09-27 2022-12-09 山东百多安医疗器械股份有限公司 一种导管流体动力学参数检测设备

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7572217B1 (en) * 2004-06-15 2009-08-11 University Of Louisville Research Foundation, Inc. System and method for providing cardiac support and promoting myocardial recovery
EP2073884B1 (en) * 2006-08-02 2018-10-10 Osprey Medical Inc. Microvascular obstruction detection and therapy
JP5922111B2 (ja) * 2010-06-23 2016-05-24 ピーツー−サイエンス・エペイエス 充血剤注入と同時に血圧測定を行う診断目的の動脈用複合カテーテル
US9877660B2 (en) 2013-11-14 2018-01-30 Medtronic Vascular Galway Systems and methods for determining fractional flow reserve without adenosine or other pharmalogical agent
CN111938616B (zh) 2014-04-04 2024-12-31 圣犹达医疗系统公司 血管内压力和流量数据诊断系统、设备和方法
WO2016195477A1 (en) * 2015-06-04 2016-12-08 Jozef Reinier Cornelis Jansen Method and computer system for processing a heart sensor output
EP3370608B1 (en) 2015-11-04 2022-06-22 Asia Pacific Medical Technology Development Company, Ltd System for quantifying flow conductance in the vasculature
CN108778149B (zh) * 2016-01-04 2021-05-04 康福乐医疗公司 用于治疗mvo的系统和方法
EP3592304B1 (en) 2017-03-20 2023-09-13 Corflow Therapeutics AG Combined stent reperfusion system
WO2019060421A1 (en) 2017-09-19 2019-03-28 Jon Helge Hoem INTRACORONARY MICROVASCULAR OBSTRUCTION CHARACTERIZATION (MVO) AND MYOCARDIAL INFARCTION
ES2992050T3 (es) * 2018-03-09 2024-12-05 Corflow Therapeutics Ag Sistema para diagnosticar y tratar obstrucciones microvasculares
JP2022501115A (ja) 2018-09-21 2022-01-06 コルフロウ セラピューティクス アーゲー 微小血管機能障害の査定のための装置

Also Published As

Publication number Publication date
US20210361170A1 (en) 2021-11-25
JP7773483B2 (ja) 2025-11-19
EP4153039B1 (en) 2026-03-25
JP2023526514A (ja) 2023-06-21
CA3179588A1 (en) 2021-11-25
WO2021234670A1 (en) 2021-11-25
EP4153039A1 (en) 2023-03-29

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