AU2021106406A4 - A formulation of medicaments using Lantana Camara for treatment of Skin related diseases and methods thereof - Google Patents

A formulation of medicaments using Lantana Camara for treatment of Skin related diseases and methods thereof Download PDF

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AU2021106406A4
AU2021106406A4 AU2021106406A AU2021106406A AU2021106406A4 AU 2021106406 A4 AU2021106406 A4 AU 2021106406A4 AU 2021106406 A AU2021106406 A AU 2021106406A AU 2021106406 A AU2021106406 A AU 2021106406A AU 2021106406 A4 AU2021106406 A4 AU 2021106406A4
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skin
soap
lantana camara
formulation
parts
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AU2021106406A
Inventor
Ashutosh Aggarwal
Ujjalkumar Das
Pankaj Gupta
Laxmi Moksha
Ajay Pal Singh
A. R. Vijayakumar
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Aggarwal Ashutosh Dr
Das Ujjalkumar Dr
Moksha Laxmi Dr
Singh Ajay Pal Dr
Vijayakumar A R Dr
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Aggarwal Ashutosh Dr
Das Ujjalkumar Dr
Moksha Laxmi Dr
Singh Ajay Pal Dr
Vijayakumar A R Dr
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    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D9/00Compositions of detergents based essentially on soap
    • C11D9/04Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
    • C11D9/22Organic compounds, e.g. vitamins
    • C11D9/38Products in which the composition is not well defined
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216Solid or semisolid forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
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  • Biotechnology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Wood Science & Technology (AREA)
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Abstract

The present invention relates to A formulation of medicaments using Lantana Camara for treatment of Skin related diseases and methods thereof. This invention particularly relates to the 5 manufacturing of Mantana Soap from Lantana camara L. for maintaining and caring of health of skin in skin disease prone human. The novel preparation of Mantana soap from plant products of Lantana camara L. will be used to care skin in human particularly those sensitive towards skin diseases. It also helps in protecting the human from many common diseases of skin such as eczema and ring worm. 11

Description

TITLE OF THE INVENTION
A formulation of medicaments using Lantana Camara for treatment of Skin related diseases and
methods thereof
FIELD OF THE INVENTION
The present invention relates to A formulation of medicaments using Lantana Camara for
treatment of Skin related diseases and methods thereof This invention particularly relates to the
manufacturing of Mantana Soap from Lantana camara L. for maintaining and caring of health of
skin in skin disease prone human. The novel preparation of Mantana soap from plant products of
Lantana camara L. will be used to care skin in human particularly those sensitive towards skin
.0 diseases. It also helps in protecting the human from many common diseases of skin such as eczema
and ring worm.
BACKGROUND OF THE INVENTION
There are many different types of soaps are avialble both commercial as well as herbal. Neem
based soap and Aloe vira containing soaps are common. Glycerine and lemon soaps are also
.5 available. Skin diseases in human take long time to be cured. There are many remedies available
in the market but they work very slowly. The commercial soaps exaggerate the problem.
CN 104920491;201510298529.0 ; HUA GUOXIONG discloses a pure natural mosquito
repellent composition which comprises the following raw materials in parts by mass: 15-18 parts
of a laurus nobilis extract, 6-10 parts of a folium eucalypti extract, 8-11 parts of a lonicerajaponica
extract, 10-15 parts of a cordate telosma extract, 5-8 parts of a lantana camara extract, 12-15 parts
of gardenia essential oil, 4-7 parts of mirabilis jalapa essential oil, 3-7 parts of lavender essential
oil, and 7-10 parts of a diluent. According to the pure natural mosquito repellent composition, pure natural traditional Chinese medicinal materials such as laurus nobilis, folium eucalypti, lonicera japonica, cordate telosma, and lantana camara are adopted, which are small in harm, the mosquitoes do not produce drug resistance, and the mosquito repellent effect is good; in addition, the pure natural gardenia essential oil, lavender essential oil, and mirabilis jalapa essential oil are added, so that the flavor is light and clear and enables people to be relaxed and happy.
CN 104906268; 201510317933.8 ; SHANG XIAOXIA discloses an externally applied
traditional Chinese medicine preparation. The externally applied traditional Chinese medicine
preparation is prepared from the following raw materials in parts by weight: 10-16 parts of bark of
.0 himalayan coralbean, 8-13 parts of blumea megacephala, 11-17 parts of cineraria repanda, 9-16
parts of hibiscus fruits, 10-14 parts of radix saposhnikoviae, 5-10 parts of herba orostachyos, 9-15
parts of ligustrum sinense, 7-13 parts of tribulus terrestris, 11-16 parts of lantana camara leaves,
8-15 parts of arcangelisia loureiri, 10-13 parts of seared cape jasmine fruits, 7-15 parts of scabrid
smallhooked hedyotis herb, 9-14 parts of viola mandshurica, 10-15 parts of majoram, 7-12 parts
.5 of lycopodium obscurum and 9-13 parts of herba pteridis semipinnatae. The externally applied
traditional Chinese medicine preparation has the good effects that the traditional Chinese medicine
preparation is easy to prepare, direct in action on affected parts, quick in effect and free of toxic
and side effects, is capable of treating both symptoms and root causes of eczema and is worthy of
wide popularization and application in clinic.
CN 104875655; 201510308270.3 ;WEI GUOYING discloses an improved full-coverage car
floor mat containing geranium essential oil is composed of a traditional Chinese medicine blank
layer, a negative ion adhesive layer and an anti-skid layer. A traditional Chinese medicine granule storage cavity and an activated mineral granule storage cavity are sequentially arranged between the traditional Chinese medicine blank layer and the anti-skid layer. Traditional Chinese medicine granules filled in the storage cavities comprise 50-60 parts of lantana camara, 1.5-2 parts of hematoxylon, 1-3 parts of ferula asafetida, 15-20 parts of folia perillae acutae, 15-20 parts of lavender, 3-5 parts of anemone hupehensis, 15-25 parts of elm barks, 4-6 parts of agilawood, 20
25 parts of camphorwood, 3-5 parts of storax, 1-3 parts of musk, 1-3 parts of mint, 1-3 parts of
berberis, 1-3 parts of schisandra chinensis, 1.5-2.5 parts of sweet marjoram and 1.5-2 parts of
sandalwood. The improved full-coverage car floor mat containing geranium essential oil is safe,
capable of effectively repelling mosquitos and releasing negative ions and fragrant and has high
.0 application value.
KR 1020150095329; 1020140016502; SONG, SANG MIN provides a method for preparing a
natural insecticide. The natural insecticide is prepared by mixing toxic ingredients such as Nerium
indicum, Arisaema amurense, Arisaema heterophyllum Blume, Cicuta virosa, Lantana camara,
.5 Scopolia japonica, Dieffenbachia, Digitalis purpurea, and Sapium japonicum with useful liquid
microorganisms and extracting and fermenting active ingredients contained in the toxic ingredients
by using the useful liquid microorganisms. Accordingly, the natural insecticide has excellent
insecticidal effects regarding harmful insects. The present invention can extract active ingredients
of toxic plants such as Nerium indicum, Arisaema amurense, Arisaema heterophyllum Blume,
Cicuta virosa, Lantana camara, Scopolia japonica, Dieffenbachia, Digitalis purpurea, and Sapium
japonicum with useful liquid microorganisms. The present reference also uses tan action of the
useful microorganisms to decompose the active ingredients of the toxic plants and synthesize novel
ingredients.
CN 104739987; 201510107156.4 ; LEI SHAOHUA discloses a traditional Chinese medicine
mixture for treating skin itch. The selected medicinal materials comprise eriocarpous glochidion
leaf, lantana camara, polygomun aviculane, polygonum multiflorum, Chinese fevervine herb and
root, caesalpinia minax, beautiful phyllodium twig and leaf, Chinese gall and egg white. The
traditional Chinese medicine mixture is capable of relieving itching, exfoliating scrub, sterilizing
and whitening the skin, and has the efficacies of clearing away heat and toxic materials, removing
stasis, relieving pain, dispelling wind, arresting itching, and relieving itching caused by mosquito
bites.
-0
CN 104645180; 201510105324.6; SUN JIANPING discloses an oral traditional Chinese medicine
preparation for relieving and treating teeth grinding in sleep. The oral traditional Chinese medicine
preparation comprises the following traditional Chinese medicine raw materials by weight: 3-5g
of Chinese tupistra rhizome, 2-7g of thalictrum aquilegifolium, 2-7g of lantana camara root, 3-7g
.5 of broadleaf sedge root, 2-1Og of radices ophiopogonis, 3-12g of Chinese fevervine herb and root,
4-8g of kaempferia galangal, 5-20g of orange pill and 3-15g of concha haliotidis. The oral
traditional Chinese medicine preparation of the invention is prepared by pure traditional Chinese
medicine raw materials and has functions of clearing stomach fire, promoting digestion to remove
stagnated food and regulate the middle warmer, reinforcing qi and nourishing blood, calming the
liver and suppressing yang, so as to effectively relieve and cure symptoms of teeth grinding in
sleep. The oral traditional Chinese medicine preparation disclosed by the invention has an obvious
effect and is not easy to relapse.
CN 104623203; 201510089745.4 ;ZANG HAIYANG discloses a traditional-Chinese
medicine composition for treating blood-deficiency and wind-dryness type eczema. The
traditional-Chinese-medicine composition is prepared from the following raw materials: axillary
choerospondias barks, java speedwell, roots of procumbent indian mallow, lantana camara leaves,
celastrus rosthornianus loes roots, rhizoma dioscoreae zingiberensis, alpina subsp imaicola, tuber
fleeceflower stems, teucrium pilosum, herb of knottedflower phyla, hairy euphorbia, three-leaf
hydrocotyle vulgaris and liquorice. The traditional-Chinese-medicine composition can be used for
treating the blood-deficiency and wind-dryness type eczema clinically.
.0 None of the prior art indicates above either alone or in combination with one another disclose what
the present invention has disclosed. Skin diseases in human take long time to be cured. There are
many remedies available in the market but they work very slowly. Sometimes doctors prescribe
steroids for treatment of skin diseases which is really not advisable and safe method for the patient.
To prevent such situation this Mantana soap has been invented to help those patients which has
.5 rough and sensitive skin prone to diseases. The uniqueness and utility of this soap is evidenced
from the fact that plant product has potential to care your skin and protect the skin from infection.
This plant has dermatitis action on skin. It can kill bacteria and fungal spored from the skin while
taking bath from it. Skin disease will be cured in definite time period as its recovery from this soap
is very fast.
SUMMARY OF THE INVENTION
The novel preparation of Mantana soap from plant products of Lantana camara L. will be used to
care skin in human particularly those sensitive towards skin diseases. It also helps in protecting
the human from many common diseases of skin such as eczema and ring worm.
It can also be used for bathing to protect the body from itching, sorisis and other skin diseases of
human without any other side effects. The prepared soap will help to recover human from many
common diseases of skin such as eczema and ring worm. It will enhance the rate of recovery of
these diseases. This preparation is quite safe from health point of view in comparison to market
available hazardous chemical based soaps. The main objectives are as follow:
• An environmentally friendly Mantana Soap preparation from plant Lantana camara L
belonging to family Verbenaceae.
• To develop skin friendly soap for sensitive skin and patients with skin diseases.
• To develop plant based soap useful to cure skin disease in human like eczema and ring
.0 worm.
DETAILED DESCRIPTION OF THE INVENTION
Lantan camara forms extensive, dense and impenetrable thickets in forestry plantations, orchards,
pasture land, waste land and in natural areas. The rapid spread of L. camara is associated with
human induced disturbance. Lantana camara L. family Verbenaceae is an exotic perennial hard
.5 woody shrub weed with beautiful clusters of flowers orange, red, yellow, multicolored (orange,
red and yellow mixed), pink, white, purple.
It can also invade forest gaps. In areas where natural fires occur they stimulate thicker regrowth.
The fallen leaves produce allelopathic substances that prevent other plants germinating and
growing beneath L. camara which results in no understory below the thickets and a "monoculture"
of the alien plant which continues to spread and adapt to drier conditions as well as invading
medium to high rainfall areas in East Africa. Rapid spread is also characteristic of wild L. camara
in East Africa such that many hundreds of hectares of both productive grazing and protected grasslands/woodlands have been observed to become heavily invaded with a few years of first infiltration from roadside infestations
Lantana camara L. family Verbenaceae is an exotic perennial hard woody shrub weed with
beautiful clusters of flowers orange, red, yellow, multicolored (orange, red and yellow mixed),
pink, white, purple.
It has great potential to kill bacteria, fungi, molds, viruses, tumors. It possesses wound healing
properties. The plant has medicinal value but no one has thought of preparation any medicine from
it. The chief ingredients of this plant are triterpenoids, essential oils, and phenolic compounds.
Bioassay studies revealed its pesticidal properties. The plant product was applied to cure human
.0 skin diseases caused by the infection of bacteria and fungi.
Introduction of skin diseases:
The most common skin diseases of human are eczema and ring worm disease. A brief description
is given below:
Eczema: It affects 9-30% of the population in India. People living in dry climates and cities are
.5 more prone to develop eczema. It can affect males as well as females.
Eczema is likely related to conditions that adversely affect the skin's barrier function (including
genetic factors, nutrient deficiencies, bacterial infection, and dry, irritated skin).
Ring Worm: Dermatophytosis, more commonly known as ringworm, is a fungal infection of the
skin. It's caused by a fungus.Ringworm infection can affect both humans and animals. The
symptoms of infection occurs as red patches on affected areas of the skin and later spreads to other
parts of the body. The infection may affect the skin of the scalp, feet, groin, beard, or other areas.
It is identified by red, itchy, scaly, or raised patches, patches that develop blisters or begin to ooze; patches that may be redder on the outside edges or resemble a ring; patches with edges that are defined and raised.
Itching: This is the most common problem of man working in the field.
The present invention can be used to wash and bath human body in all types of skin diseases. It
will protect the skin from further deterioration. Washing from soap before applying ointment will
cure the skin at faster rate.
Working Example:
The first step is of the present invention is preparation of Lantana Extract: Lantana camara is a
unique medicinal plant. In present invention, the extract the photochemical present, and do
.0 extractions with organic and polar solvents. For the polar solvent (water and partly methanol),
hence we will extract all polar compounds and can fractionate them and do mass spectrometry and
NMR to identify them. For the organic solvent extractions, done sequential extractions with a
number of organic solvents. Then we can carry out mass spectrometry to determine the
compounds.
.5 Further, Twigs of Lantana camara L. done and Active plant part immersed in water for 2-3 days
and Boil and Sieve in muslin cloth.
Next, Mixing the Soya bean oil and coconut oil in a pan and Warm gently the mixer of two
oils in a heavy pan and heat to 50°C. Take 1 litre of water in a heavy pan. Measure Sodium
hydroxide (NaoH) and add it slowly to water (one Litre) and stir slowly until dissolved. It is
exothermic reaction so never add water to sodium hydroxide or never touch with finger. It will
burn otherwise. Allow the mixer of sodium hydroxide and water to cool about 60 degree. Pour
mixer of sodium hydroxide and water in a heavy pan having mixer of two oils. Stir continuously
and vigorously. After some time soap will be separated from the rest of the solution. Add glycerine and plant extract to the soap paste. The soap will be solidified in few hours. So as to, Transparent pink Mantana Soap is formed very effective in controlling skin diseases and keeping skin healthy in normal skin.
Formulation:
1 Lantana Extract
2 Soya bean oil
3 coconut oil
4 Sodium hydroxide
5 water
6 Glycerin

Claims (4)

Claims:
1. A formulation of medicaments using Lantana Camara for treatment of Skin related diseases.
2. The formulation as claimed in claim 1, wherein said formulation comprises Plant product i.e. a
part of Lantana camara L. of family Verbenaceae, Castic soda, Oil and other soap making
ingredients.
3. A method of preparation of formulation of medicaments using Lantana Camara for treatment of
Skin related diseases.
4. The method as claimed in claim 1, wherein said is comprising the steps of extracting, twigging,
active plant part immersed in water for 72 hrs, boil and Sieve in muslin cloth, Mixing Soya bean
oil and coconut oil in a pan, Warming gently the mixer of two oils in a heavy pan and heat to 50°C,
taking 1 litre of water in a heavy pan, Measure Sodium hydroxide (NaoH) and add it slowly to
water (one Litre) and stir slowly until dissolved; Allow the mixer of sodium hydroxide and water
to cool about 60 degree; Pour mixer of sodium hydroxide and water in a heavy pan having mixer
of two oils; Stir continuously and vigorously; After some time soap will be separated from the rest
of the solution; Adding glycerine and plant extract to the soap paste; the soap will be solidified in
few hours.1
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