AU2020414152B2 - Application of fusion protein in treating age-related macular degeneration - Google Patents

Application of fusion protein in treating age-related macular degeneration Download PDF

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Publication number
AU2020414152B2
AU2020414152B2 AU2020414152A AU2020414152A AU2020414152B2 AU 2020414152 B2 AU2020414152 B2 AU 2020414152B2 AU 2020414152 A AU2020414152 A AU 2020414152A AU 2020414152 A AU2020414152 A AU 2020414152A AU 2020414152 B2 AU2020414152 B2 AU 2020414152B2
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eye
ibi302
group
administration
injection
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AU2020414152A
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AU2020414152A1 (en
Inventor
Shujie Lu
Lei Qian
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Innovent Biologics Suzhou Co Ltd
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Innovent Biologics Suzhou Co Ltd
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Priority to AU2025203373A priority Critical patent/AU2025203373A1/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2020414152A 2019-12-24 2020-12-23 Application of fusion protein in treating age-related macular degeneration Active AU2020414152B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2025203373A AU2025203373A1 (en) 2019-12-24 2025-05-09 Application Of Fusion Protein In Treating Age-Related Macular Degeneration

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CN201911346311.2 2019-12-24
CN201911346311 2019-12-24
CN202011441025 2020-12-11
CN202011441025.7 2020-12-11
PCT/CN2020/138598 WO2021129658A1 (zh) 2019-12-24 2020-12-23 融合蛋白在治疗年龄相关性黄斑变性中的应用

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2025203373A Division AU2025203373A1 (en) 2019-12-24 2025-05-09 Application Of Fusion Protein In Treating Age-Related Macular Degeneration

Publications (2)

Publication Number Publication Date
AU2020414152A1 AU2020414152A1 (en) 2022-08-04
AU2020414152B2 true AU2020414152B2 (en) 2025-02-13

Family

ID=76575187

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2020414152A Active AU2020414152B2 (en) 2019-12-24 2020-12-23 Application of fusion protein in treating age-related macular degeneration
AU2025203373A Pending AU2025203373A1 (en) 2019-12-24 2025-05-09 Application Of Fusion Protein In Treating Age-Related Macular Degeneration

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2025203373A Pending AU2025203373A1 (en) 2019-12-24 2025-05-09 Application Of Fusion Protein In Treating Age-Related Macular Degeneration

Country Status (8)

Country Link
US (1) US20230056821A1 (https=)
EP (1) EP4082559A4 (https=)
JP (2) JP2023509880A (https=)
CN (2) CN118750581A (https=)
AU (2) AU2020414152B2 (https=)
CA (1) CA3165887A1 (https=)
TW (2) TWI879855B (https=)
WO (1) WO2021129658A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118718181A (zh) 2019-06-05 2024-10-01 里珍纳龙药品有限公司 用于精确剂量递送的装置及方法
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
CN117467025B (zh) * 2023-12-28 2024-04-16 上海鼎新基因科技有限公司 一种抗vegf和补体双功能融合蛋白及其应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013082563A1 (en) * 2011-12-01 2013-06-06 Protevobio, Inc. Protein inhibitors to complement and vegf pathways and methods of use thereof
US10071136B2 (en) * 2014-09-25 2018-09-11 Innovent Biologics, Inc. Stable liquid formulations of recombinant fusion proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105435222B (zh) * 2014-09-25 2018-05-29 信达生物制药(苏州)有限公司 重组融合蛋白制剂

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013082563A1 (en) * 2011-12-01 2013-06-06 Protevobio, Inc. Protein inhibitors to complement and vegf pathways and methods of use thereof
US10071136B2 (en) * 2014-09-25 2018-09-11 Innovent Biologics, Inc. Stable liquid formulations of recombinant fusion proteins

Also Published As

Publication number Publication date
EP4082559A4 (en) 2024-01-03
CN114867489A (zh) 2022-08-05
AU2025203373A1 (en) 2025-05-29
EP4082559A1 (en) 2022-11-02
AU2020414152A1 (en) 2022-08-04
CN118750581A (zh) 2024-10-11
US20230056821A1 (en) 2023-02-23
TWI879855B (zh) 2025-04-11
CA3165887A1 (en) 2021-07-01
JP2024167222A (ja) 2024-12-03
WO2021129658A1 (zh) 2021-07-01
TW202525865A (zh) 2025-07-01
TW202128746A (zh) 2021-08-01
JP2023509880A (ja) 2023-03-10

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