AU2020346456A1 - TAK-925 for use in treating narcolepsy - Google Patents

TAK-925 for use in treating narcolepsy Download PDF

Info

Publication number
AU2020346456A1
AU2020346456A1 AU2020346456A AU2020346456A AU2020346456A1 AU 2020346456 A1 AU2020346456 A1 AU 2020346456A1 AU 2020346456 A AU2020346456 A AU 2020346456A AU 2020346456 A AU2020346456 A AU 2020346456A AU 2020346456 A1 AU2020346456 A1 AU 2020346456A1
Authority
AU
Australia
Prior art keywords
compound
subject
methyl
administration
plasma concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2020346456A
Other languages
English (en)
Inventor
Rebecca Evans
Helene FAESSEL
Deborah Hartman
Shinichiro Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Publication of AU2020346456A1 publication Critical patent/AU2020346456A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2020346456A 2019-09-13 2020-09-12 TAK-925 for use in treating narcolepsy Abandoned AU2020346456A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962900298P 2019-09-13 2019-09-13
US62/900,298 2019-09-13
US202063031686P 2020-05-29 2020-05-29
US63/031,686 2020-05-29
PCT/IB2020/058483 WO2021048822A1 (en) 2019-09-13 2020-09-12 Tak-925 for use in treating narcolepsy

Publications (1)

Publication Number Publication Date
AU2020346456A1 true AU2020346456A1 (en) 2022-04-14

Family

ID=72560858

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020346456A Abandoned AU2020346456A1 (en) 2019-09-13 2020-09-12 TAK-925 for use in treating narcolepsy

Country Status (11)

Country Link
US (1) US20220339143A1 (https=)
EP (1) EP4028004A1 (https=)
JP (1) JP2022547711A (https=)
KR (1) KR20220062012A (https=)
CN (1) CN114980892A (https=)
AU (1) AU2020346456A1 (https=)
BR (1) BR112022004587A2 (https=)
CA (1) CA3154321A1 (https=)
CO (1) CO2022004596A2 (https=)
MX (1) MX2022003018A (https=)
WO (1) WO2021048822A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220062361A (ko) * 2019-09-13 2022-05-16 다케다 야쿠힌 고교 가부시키가이샤 과도한 졸림의 치료를 위한 오렉신 2 수용체 효능제의 용도
AU2021205892B2 (en) 2020-01-10 2026-04-23 Takeda Pharmaceutical Company Limited A method for enhancing the pharmacokinetics or increasing the plasma concentration of methyl 3-((methylsulfonyl)amino)-2-(((4-phenylcyclohexyl)oxy)methyl)piperidine-1-carboxylate or a salt thereof with an inhibitor of cytochrome P450
CN116583502A (zh) 2020-09-03 2023-08-11 欧瑞夏治疗有限公司 二环-杂环衍生物及其作为食欲素-2受体激动剂的用途
US20240165092A1 (en) * 2021-04-02 2024-05-23 Takeda Pharmaceutical Limited Company Use of an orexin 2 receptor agonist for post operation recovery
IL316468A (en) 2022-04-22 2024-12-01 Teijin Pharma Ltd The aftermath of oxazepine
WO2024075825A1 (ja) 2022-10-07 2024-04-11 キッセイ薬品工業株式会社 シクロペンタン化合物
EP4611745A1 (en) * 2022-10-31 2025-09-10 Takeda Pharmaceutical Company Limited Dosing of orexin type 2 receptor agonists
TW202535890A (zh) 2023-10-20 2025-09-16 日商帝人製藥股份有限公司 氧氮呯衍生物之結晶或其溶劑合物之結晶
WO2025124698A1 (en) 2023-12-12 2025-06-19 Idorsia Pharmaceuticals Ltd Aryl sulfone and sulfanone derivatives as orexin receptor modulators
TW202542165A (zh) 2023-12-19 2025-11-01 瑞士商愛杜西亞製藥有限公司 大環食慾素激動劑
WO2025229493A1 (en) * 2024-04-29 2025-11-06 Takeda Pharmaceutical Company Limited Dosing of orexin type 2 receptor agonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0815134B1 (en) 1995-03-14 2002-06-05 Praecis Pharmaceuticals Incorporated Modulators of amyloid aggregation
PT929574E (pt) 1996-08-27 2005-11-30 Praecis Pharm Inc Moduladores da agregacao de peptidos beta-amiloides compreendendo d-aminoacidos
EP1196609A2 (en) 1999-06-28 2002-04-17 Oklahoma Medical Research Foundation Catalytically active recombinant memapsin and methods of use thereof
MX376164B (es) * 2014-10-23 2025-03-07 Eisai R&D Man Co Ltd Composiciones y metodos para tratar el insomnio.
WO2016201373A1 (en) * 2015-06-12 2016-12-15 Axovant Sciences Ltd. Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder
LT3984994T (lt) * 2016-02-04 2024-10-10 Takeda Pharmaceutical Company Limited Pakeistas piperidino junginys kaip 2 tipo oreksino agonistas narkolepsijai gydyti

Also Published As

Publication number Publication date
CA3154321A1 (en) 2021-03-18
JP2022547711A (ja) 2022-11-15
EP4028004A1 (en) 2022-07-20
CN114980892A (zh) 2022-08-30
KR20220062012A (ko) 2022-05-13
WO2021048822A1 (en) 2021-03-18
BR112022004587A2 (pt) 2022-06-14
US20220339143A1 (en) 2022-10-27
MX2022003018A (es) 2022-06-14
CO2022004596A2 (es) 2022-08-30

Similar Documents

Publication Publication Date Title
AU2020346456A1 (en) TAK-925 for use in treating narcolepsy
US20220331303A1 (en) Use of an orexin 2 receptor agonist for the treatment of excessive sleepiness
US12594269B2 (en) Method for enhancing the pharmacokinetics or increasing the plasma concentration of methyl 3-((methylsulfonyl)amino)-2-(((4-phenylcyclohexyl)oxy)methyl)piperidine-1-carboxylate or a salt thereof with an inhibitor of cytochrome P450
WO2024095158A1 (en) Dosing of orexin type 2 receptor agonists
JP2015509931A (ja) 医薬的な組み合わせ
Napoliello et al. Buspirone: a worldwide update
JP7607864B2 (ja) Kv7チャネル活性化剤の使用方法
AU2022252108A1 (en) Use of an orexin 2 receptor agonist for post operation recovery
WO2022190060A1 (en) An orexin 2 receptor agonist for the treatment of an orexin-mediated disease or disorder
US20090306050A1 (en) Treatment and prevention of depression with pain, depression secondary to pain, and of neuropathic pain
JP2008514689A (ja) Adhd、cfs、fmおよび鬱病の処置のためのロフェプラミンの薬学的な組成物の使用
HK40113570A (en) Methods of use for kv7 channel activators
CA3270681A1 (en) Dosing of orexin type 2 receptor agonists
JP2010513227A (ja) 覚醒を促進するためのIhチャネル阻害剤
Kompoliti et al. Non‐Parkinsonian Movement Disorders
HK40000275B (en) Compounds having melatonin receptor affinity as prophylactic or therapeutic agent for delirium

Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application